Zobrazeno 1 - 10
of 53
pro vyhledávání: '"J L, Gollan"'
Publikováno v:
Journal of Lipid Research, Vol 22, Iss 3, Pp 431-436 (1981)
The primary determinants of hepatic uptake of long chain fatty acids have been considered to be the plasma concentrations of fatty acid and albumin, with little or no intrinsic control by the hepatocyte itself. However, recent studies of liver cell s
Externí odkaz:
https://doaj.org/article/6f64964737de4cacb261805c7f581468
Publikováno v:
Journal of Lipid Research, Vol 29, Iss 2, Pp 144-156 (1988)
The role of the hepatocyte microtubular system in the transport and excretion of bile salts and biliary lipid has not been defined. In this study the effects of microtubule inhibition on biliary excretion of micelle- and non-micelle-forming bile salt
Externí odkaz:
https://doaj.org/article/8f1a03d574134431982629b3a42d7794
Autor:
J. L. Gollan, Nelson B. Freimer, J. G. Fitz, James L. Boyer, Allan W. Wolkoff, P. D. Berk, Frederick J. Suchy, R. H. Moseley, B. F. Scharschmidt, P. J. Meier
Publikováno v:
Hepatology. 28:1713-1719
Publikováno v:
Hepatology. 24:979-986
Chronic viral hepatitis frequently goes undetected until cirrhosis develops. Although the effect of interferon on the natural history of hepatitis B virus (HBV) or hepatitis C virus (HCV) infection in asymptomatic persons is unknown, treatment may mo
Publikováno v:
Hepatology (Baltimore, Md.). 22(4 Pt 1)
Tumor necrosis factor-alpha (TNF alpha), a cytokine that is produced in a variety of inflammatory diseases associated with cholestasis, is believed to be the primary mediator of the systemic effects of endotoxin. Thus, we have investigated the role o
Publikováno v:
The Journal of biological chemistry. 270(3)
Unconjugated bilirubin is transported in the plasma bound primarily to serum albumin, from which it is taken up and metabolized by the liver. To better characterize the mechanism of bilirubin delivery to the hepatocyte, stopped-flow techniques were u
Publikováno v:
The American journal of physiology. 267(6 Pt 1)
The potential effects of cytokines on hepatocellular transport functions remain undefined. Interleukin-6 (IL-6) is a cytokine that is produced in sepsis, hepatitis, and other inflammatory conditions often associated with cholestasis. Using cultured r
Publikováno v:
The Journal of biological chemistry. 268(31)
beta-Glucuronidase is an acid hydrolase located in both the lysosomal and microsomal compartments of the hepatocyte. The function of the latter remains undefined. We postulated that microsomal beta-glucuronidase may be responsible for the deconjugati
Publikováno v:
Cancer research. 52(11)
To search for differentially expressed gene products in selected cancers of endodermal origin, cDNA libraries derived from mRNA in human hepatocellular carcinoma and adjacent grossly normal tissue were generated. From these parent libraries, subtract
Autor:
S C, Hauser, J L, Gollan
Publikováno v:
Progress in liver diseases. 9