Zobrazeno 1 - 7
of 7
pro vyhledávání: '"J L, Frestedt"'
Autor:
Gaston K. Rivera, C H Pui, Qing Liu, James R. Downing, Frederick G. Behm, J. H. Kersey, William M. Crist, J. L. Frestedt, Susana C. Raimondi
Publikováno v:
Blood. 87:2870-2877
MLL gene rearrangements are associated with an extremely poor prognosis in infants with acute lymphoblastic leukemia (ALL), but little is known about their clinical significance in older children. Therefore, we studied 45 cases of childhood ALL with
Autor:
C H Pui, J. L. Frestedt, David R. Head, J. H. Kersey, James R. Downing, Frederick G. Behm, Susana C. Raimondi
Publikováno v:
Blood. 86:1881-1886
Balanced translocations affecting the 11q23 region are among the most frequent chromosomal abnormalities in childhood acute lymphoblastic leukemia (ALL), comprising 5% to 6%. These cases consistently have a rearranged MLL gene and are associated with
Publikováno v:
Blood. 92(10)
Acute leukemia with t(4;11)(q21,q23) translocation results from the in-frame fusion of the MLL to the AF4/FEL gene. In previous studies, we and others demonstrated that AF4 transcripts are present in a variety of hematopoietic and nonhematopoietic hu
Autor:
J M, Hilden, F O, Smith, J L, Frestedt, R, McGlennen, W B, Howells, P H, Sorensen, D C, Arthur, W G, Woods, J, Buckley, I D, Bernstein, J H, Kersey
Publikováno v:
Blood. 89(10)
To study prognostic factors in infant acute myeloid leukemia (AML), we analyzed 44 children treated on Childrens Cancer Group protocols for MLL gene rearrangement by Southern blot, cytogenetic 11q23 abnormalities, and reactivity with monoclonal antib
Autor:
F G, Behm, S C, Raimondi, J L, Frestedt, Q, Liu, W M, Crist, J R, Downing, G K, Rivera, J H, Kersey, C H, Pui
Publikováno v:
Blood. 87(7)
MLL gene rearrangements are associated with an extremely poor prognosis in infants with acute lymphoblastic leukemia (ALL), but little is known about their clinical significance in older children. Therefore, we studied 45 cases of childhood ALL with
Publikováno v:
Blood. 86(10)
Molecular techniques to detect MLL (11q23) and AF-4 (4q21) gene rearrangements are being evaluated for use in stratification of patients into prognostic groups. We studied 15 cases of infant acute lymphoblastic leukemia (ALL) with Southern blotting f
Publikováno v:
Blood. 86(5)
Balanced translocations affecting the 11q23 region are among the most frequent chromosomal abnormalities in childhood acute lymphoblastic leukemia (ALL), comprising 5% to 6%. These cases consistently have a rearranged MLL gene and are associated with