Zobrazeno 1 - 10
of 107
pro vyhledávání: '"J L, Cuche"'
Publikováno v:
Journal of the Autonomic Nervous System. 80:46-51
Noradrenaline (NA) kinetics represent an effective tool for evaluating the activity of the sympathetic system: thus plasma NA concentration, spillover rate (SOR) and metabolic clearance rate (MC) were measured in the rat. The dilution technique was a
Publikováno v:
Life Sciences. 60:357-367
The aim of the present study was to investigate the possible role of erythrocytes in the metabolic clearance of catecholamines (CAs) in the rat. Intravenous infusion of exogenous CAs (dopamine -DA-, norepinephrine -NE-, or epinephrine -Epi-) was carr
Publikováno v:
Journal of Applied Physiology. 80:1390-1396
The aim of the present study as to investigate whether increased central hypervolemia induced by tail suspension (TS) in the rat is an appropriate model of cardiovascular deconditioning (CVD). First, the physiological relationship between central ven
Autor:
M. E. Safar, Patrick Lacolley, Eric Martel, Pascal Champeroux, J. L. Cuche, Stéphane Laurent, Anne-Marie Brisac
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 267:H2407-H2412
Experiments were performed on conscious chronically instrumented rats maintained on tail suspension to determine the time course of changes in baroreceptor control of heart rate produced by this procedure. Pressor responses were elicited by bolus inj
Autor:
J. L. Cuche, Alain P. Guerin, Bruno Pannier, Gérard M. London, Michel E. Safar, S. J. Marchais
Publikováno v:
Circulation. 90:2786-2796
BACKGROUND We wished to assess the respective roles of the antihypertensive and blood pressure (BP)-independent effects of antihypertensive drugs on arterial hemodynamics and left ventricular hypertrophy (LVH) in end-stage renal disease (ESRD) patien
Autor:
Joëlle Schneider, Patrick Lacolley, Anne-Marie Brisac, J. L. Cuche, Dong Wen-Xin, Michel E. Safar
Publikováno v:
Journal of the Autonomic Nervous System. 44:109-117
Pre-synaptic endings of the sympathetic nervous fibers control the metabolism of catecholamines, particularly inactivating norepinephrine after its neuronal recapture. The present study was carried out to investigate this segment of the metabolism of
Publikováno v:
Journal of Hypertension. 10:355-360
Objective: To investigate the hemodynamic effects of a moderately low-salt diet in a 9-week, randomized, double-blind, crossover study in 20 hypertensive, ambulatory patients. Methods: All subjects followed a 9-week, low-salt diet. During this period
Autor:
Patrice Jaillon, B. Lecocq, P Sauleman, A Rames, J L Cuche, Jean-Marie Poirier, F Le Coz, M Midavaine
Publikováno v:
Journal of Cardiovascular Pharmacology. 18:28-34
The effects of exercise on bisoprolol oral pharmacokinetics were studied in eight healthy male volunteers in an open, randomized, three-period, crossover trial. Oral bisoprolol (20 mg) was given either at rest during 24 h or with iterative stress tes
Publikováno v:
European Heart Journal. 11:17-23
The load of the heart in hypertension is related not only to increased peripheral vascular resistance but also to decreased aortic compliance. From non-invasive clinical studies involving determinations of pulse wave velocity and systolic-diastolic v
Publikováno v:
Life Sciences. 47:2003-2008
Restraint stress is known to induce gastric ulcers in rats. Peripheral sympathetic activity and catecholamines are involved in the pathogenesis of these gastric ulcers. The aim of the present study was to evaluate the effects of restraint on mucosal