Zobrazeno 1 - 10
of 18
pro vyhledávání: '"J L, Caffrey"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 285:H1332-H1339
Methionine-enkephalin-arginine-phenylalanine (MEAP) introduced into the interstitium of the canine sinoatrial (SA) node by microdialysis interrupts vagal bradycardia. In contrast, raising endogenous MEAP by occluding the SA node artery improves vagal
Autor:
J. L. Caffrey, Antoine Younes, Edward G. Lakatta, Lydia O'Neill, B. A. Barron, Marvin O. Boluyt, Michael T. Crow
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 265:H212-H218
Several lines of evidence suggest that opioid peptide production in the heart may increase during aging from adulthood through senescence. We tested the hypothesis that cardiac opioid peptides and preproenkephalin (PNK) mRNA would increase with advan
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(2)
Short-term morphine stimulates vagal bradycardia. This led us to propose the hypothesis that chronically administered morphine would down-regulate myocardial muscarinic receptor systems. Dogs received morphine continuously for 2 weeks through an s.c.
Publikováno v:
Circulatory shock. 32(4)
Naloxone potentiates the inotropic effect of selected beta-agonists in the canine isolated heart. This could be accomplished by elevating circulating catecholamines through a reduction in their disposal or by the facilitation of events at or subseque
Publikováno v:
Circulatory shock. 31(3)
The beneficial pressor effects of naloxone in shock have been associated with existing adrenergic systems and in particular with circulating epinephrine. Vascular interactions among alpha adrenergic receptor agents, naloxone, and selected opioids wer
Publikováno v:
Progress in clinical and biological research. 328
Publikováno v:
Experimental Biology and Medicine. 152:366-371
SummaryA simple and highly reproducible method was developed for the dissociation of ovine luteal tissue into isolated cell suspensions using a crude collagenase preparation in Medium 199. The procedure required less than 3 hr. The mean yield of cell
Publikováno v:
Biology of Reproduction. 21:601-608
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 250:H749-H754
Intracoronary injection of naloxone produces rapid local increases in myocardial performance. The role of beta-adrenergic activation in this response was investigated. Naloxone was injected into the left anterior descending artery (LAD) of anesthetiz
Publikováno v:
Biology of Reproduction. 20:279-287
The 3j3-hydroxy-�-steroid dehydrogenase/�15-�14-isomerase complex (IISO) is responsible for the conversion of pregnenolone to progesterone. In the ovine corpus luteum, HSD activity was found to be localized in the microsomal fraction and the ac