Výsledky vyhledávání - "J L, CLEVELAND"

Ornithine decarboxylase is a mediator of c-Myc-induced apoptosis

Autor: G Packham, J L Cleveland

Publikováno v: Molecular and Cellular Biology. 14:5741-5747

c-Myc plays a central role in the regulation of cell cycle progression, differentiation, and apoptosis. However, the proteins which mediate c-Myc function(s) remain to be determined. Enforced c-myc expression rapidly induces apoptosis in interleukin-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9129d8327a6f73494c5c90623af40c5a
https://doi.org/10.1128/mcb.14.9.5741

Zobrazit plný text záznamu

Identification of novel protein tyrosine phosphatases of hematopoietic cells by polymerase chain reaction amplification

Autor: T, Yi, J L, Cleveland, J N, Ihle

Publikováno v: Blood. 78:2222-2228

Polymerase chain reaction (PCR) conditions were used to amplify cDNAs that encode putative protein tyrosine phosphatases (PTPs) from a murine interleukin-3-dependent myeloid cell line. Primers for the reactions were based on conserved sequences of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25633dc8b0cd7af95de244e26e1a9be8
https://doi.org/10.1182/blood.v78.9.2222.bloodjournal7892222

Zobrazit plný text záznamu

Suppression of c-myc expression and c-Myc function in response to sustained DNA damage in MCF-7 breast tumor cells

Autor: K J, Magnet, M S, Orr, J L, Cleveland, C, Rodriguez-Galindo, H, Yang, C, Yang, Y M, Di, P T, Jain, D A, Gewirtz

Publikováno v: Biochemical pharmacology. 62(5)

The topoisomerase II inhibitors teniposide (VM-26), doxorubicin, and amsacrine (m-AMSA), as well as ionizing radiation, induce a transient suppression of c-myc mRNA, which correlates with growth inhibition of MCF-7 breast tumor cells. To further asse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0481dc58dc826a8328bad0efab9bf73a
https://pubmed.ncbi.nlm.nih.gov/11585056

Zobrazit plný text záznamu

EBV regulates c-MYC, apoptosis, and tumorigenicity in Burkitt's lymphoma

Autor: I K, Ruf, P W, Rhyne, H, Yang, C M, Borza, L M, Hutt-Fletcher, J L, Cleveland, J T, Sample

Publikováno v: Current topics in microbiology and immunology. 258

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bb1cbec5475bb03f4412a93ca7baf1ff
https://pubmed.ncbi.nlm.nih.gov/11443860

Zobrazit plný text záznamu

The polyamine oxidase inhibitor MDL-72,527 selectively induces apoptosis of transformed hematopoietic cells through lysosomotropic effects

Autor: H, Dai, D L, Kramer, C, Yang, K G, Murti, C W, Porter, J L, Cleveland

Publikováno v: Cancer research. 59(19)

Polyamine oxidase functions in the polyamine catabolic pathway, converting N1-acetyl-spermidine and -spermine into putrescine (Put) and spermidine (Spd), respectively, thereby facilitating homeostasis of intracellular polyamine pools. Inhibition of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e8a7ce28b6df2e2116cf3cdecda536f7
https://pubmed.ncbi.nlm.nih.gov/10519408

Zobrazit plný text záznamu

Risk and prevention of hepatitis C virus infection. Implications for dentistry

Autor: J L, Cleveland, B F, Gooch, B G, Shearer, R L, Lyerla

Publikováno v: Journal of the American Dental Association (1939). 130(5)

The occupational risk of hepatitis C virus, or HCV, infection in dentistry is very low. Nonetheless, the lack of an effective vaccine, the high rates of chronic infection and the limited effectiveness of treatment may cause concern for dental workers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5cde1f9afbc03dcd6652bee4d8a03d15
https://pubmed.ncbi.nlm.nih.gov/10332128

Zobrazit plný text záznamu

E2F-1 and E2F-3 are functionally distinct in their ability to promote myeloid cell cycle progression and block granulocyte differentiation

Autor: D K, Strom, J L, Cleveland, S, Chellappan, J, Nip, S W, Hiebert

Publikováno v: Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 9(1)

Interleukin 3 (IL-3)-dependent 32D.3 myeloid cells are an attractive model system for the analysis of hematopoietic cell growth, differentiation, and apoptosis. In these cells, E2F-3, E2F-4, and DP-1 are regulated by both IL-3 and granulocyte colony-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c99a4f185ec7488628e5c107dd642a2
https://pubmed.ncbi.nlm.nih.gov/9438389

Zobrazit plný text záznamu

c-Myc induces apoptosis and cell cycle progression by separable, yet overlapping, pathways

Autor: G, Packham, C W, Porter, J L, Cleveland

Publikováno v: Oncogene. 13(3)

Enforced c-Myc expression promotes inappropriate cell cycle progression of growth factor deprived cells and triggers concomitant apoptosis. However, it is not clear what role dysregulation of the cell cycle plays in c-Myc-induced apoptosis. Ornithine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a53140257daa12a175bbb601da4f02c6
https://pubmed.ncbi.nlm.nih.gov/8760287

Zobrazit plný text záznamu

Cytokines suppress apoptosis independent of increases in reactive oxygen levels

Autor: G, Packham, R A, Ashmun, J L, Cleveland

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 156(8)

Antioxidants suppress apoptosis induced by diverse stimuli in many cells, including immune cells, suggesting that reactive oxygen species (ROS) are common mediators of apoptosis. We evaluated the potential role for ROS in the apoptosis of myeloid pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::828fd42042353775bff5e8d69fdf9b20
https://pubmed.ncbi.nlm.nih.gov/8609398

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání