Zobrazeno 1 - 10
of 592
pro vyhledávání: '"J Kutzner"'
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1911 (2023)
Kidney disease is a growing public health problem worldwide, including both acute and chronic forms. Existing therapies for kidney disease target various pathogenic mechanisms; however, these therapies only slow down the progression of the disease ra
Externí odkaz:
https://doaj.org/article/1e73e77402f743ffb72d35904647aa3c
Akademický článek
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Autor:
Mare Cudic, Nicolai V. Bovin, Herbert Kaltner, Joachim C. Manning, Donella Beckwith, Fred Sinowatz, Anna-Kristin Ludwig, Paul V. Murphy, Tanja J Kutzner, Adele Gabba, Hans-Joachim Gabius, Gabriel García Caballero, Nadezhda Shilova
Publikováno v:
Histochemistry and Cell Biology
Histochem Cell Biol
Histochem Cell Biol
The concept of biomedical significance of the functional pairing between tissue lectins and their glycoconjugate counterreceptors has reached the mainstream of research on the flow of biological information. A major challenge now is to identify the p
Autor:
Gabriel, García Caballero, Joachim C, Manning, Adele, Gabba, Donella, Beckwith, Forrest G, FitzGerald, Tanja J, Kutzner, Anna-Kristin, Ludwig, Herbert, Kaltner, Paul V, Murphy, Mare, Cudic, Hans-Joachim, Gabius
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2442
Dynamic changes of a cell's glycophenotype are increasingly interpreted as shifts in the capacity to interact with tissue (endogenous) lectins. The status of glycan branching or chain length (e.g., core 1 vs core 2 mucin-type O-glycans and polyLacNAc
Autor:
Tanja J, Kutzner, Alonso M, Higuero, Martina, Süßmair, Michael, Hingar, Herbert, Kaltner, Ingo, Lindner, Jürgen, Kopitz, José, Abad-Rodríguez, Dietmar, Reusch, Hans-Joachim, Gabius
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2442
Mammalian galectins have no signal peptide, and it is not known what would happen if a galectin is directed to take the classical export route. The corresponding engineering of galectin-specific cDNA will answer questions on the fate of a signal pept
Autor:
Tanja J. Kutzner, Alonso M. Higuero, Martina Süßmair, Michael Hingar, Herbert Kaltner, Ingo Lindner, Jürgen Kopitz, José Abad-Rodríguez, Dietmar Reusch, Hans-Joachim Gabius
Publikováno v:
Methods in Molecular Biology ISBN: 9781071620540
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5efda66c970d6f41c65a3aac33e4657
https://doi.org/10.1007/978-1-0716-2055-7_15
https://doi.org/10.1007/978-1-0716-2055-7_15
Autor:
Gabriel García Caballero, Joachim C. Manning, Adele Gabba, Donella Beckwith, Forrest G. FitzGerald, Tanja J. Kutzner, Anna-Kristin Ludwig, Herbert Kaltner, Paul V. Murphy, Mare Cudic, Hans-Joachim Gabius
Publikováno v:
Methods in Molecular Biology ISBN: 9781071620540
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f3272b7fffee9e4161070b702b261fa
https://doi.org/10.1007/978-1-0716-2055-7_17
https://doi.org/10.1007/978-1-0716-2055-7_17
Autor:
Joachim C. Manning, Veronica Baldoneschi, Laura L. Romero-Hernández, Katharina M. Pichler, Gabriel GarcÍa Caballero, Sabine André, Tanja J. Kutzner, Anna-Kristin Ludwig, Valerio Zullo, Barbara Richichi, Reinhard Windhager, Herbert Kaltner, Stefan Toegel, Hans-Joachim Gabius, Paul V. Murphy, Cristina Nativi
Publikováno v:
Bioorganic & Medicinal Chemistry. 75:117068
Pairing glycans with tissue lectins controls multiple effector pathways in (patho)physiology. A clinically relevant example is the prodegradative activity of galectins-1 and -3 (Gal-1 and -3) in the progression of osteoarthritis (OA) via matrix metal
Autor:
Hans-Joachim Gabius, Forrest G FitzGerald, Mark Kriegsmann, Paul V. Murphy, Malwina Michalak, Tanja J Kutzner, Anna-Kristin Ludwig, Mare Cudic, Donella Beckwith, Joachim C. Manning, Gabriel García Caballero, Herbert Kaltner, Adele Gabba, Jürgen Kopitz
Publikováno v:
Histochemistry and cell biology. 156(3)
Wild-type lectins have distinct types of modular design. As a step to explain the physiological importance of their special status, hypothesis-driven protein engineering is used to generate variants. Concerning adhesion/growth-regulatory galectins, n
Autor:
Gabriel, García Caballero, Herbert, Kaltner, Tanja J, Kutzner, Anna-Kristin, Ludwig, Joachim C, Manning, Sebastian, Schmidt, Fred, Sinowatz, Hans-Joachim, Gabius
Publikováno v:
Histology and histopathology. 35(6)
Having identified glycans of cellular glycoconjugates as versatile molecular messages, their recognition by sugar receptors (lectins) is a fundamental mechanism within the flow of biological information. This type of molecular interplay is increasing