Zobrazeno 1 - 10
of 1 988
pro vyhledávání: '"J Krebs"'
Autor:
Elizabeth J. Martinez, William C. Chang, Wei-Hung Chen, Agnes Hajduczki, Paul V. Thomas, Jaime L. Jensen, Misook Choe, Rajeshwer S. Sankhala, Caroline E. Peterson, Phyllis A. Rees, Jordan Kimner, Sandrine Soman, Caitlin Kuklis, Letzibeth Mendez-Rivera, Vincent Dussupt, Jocelyn King, Courtney Corbett, Sandra V. Mayer, Aldon Fernandes, Kripa Murzello, Tres Cookenham, Janine Hvizdos, Larry Kummer, Tricia Hart, Kathleen Lanzer, Julian Gambacurta, Matthew Reagan, Debbie Duso, Sandhya Vasan, Natalie D. Collins, Nelson L. Michael, Shelly J. Krebs, Gregory D. Gromowski, Kayvon Modjarrad, John Kaundinya, M. Gordon Joyce
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110624- (2024)
Summary: The rapid emergence of SARS-CoV-2 variants of concern (VoC) and the threat of future zoonotic sarbecovirus spillover emphasizes the need for broadly protective next-generation vaccines and therapeutics. We utilized SARS-CoV-2 spike ferritin
Externí odkaz:
https://doaj.org/article/d044a7b730b34c81a3817a63324aa1dd
Autor:
Hongjun Bai, Eric Lewitus, Yifan Li, Paul V. Thomas, Michelle Zemil, Mélanie Merbah, Caroline E. Peterson, Thujitha Thuraisamy, Phyllis A. Rees, Agnes Hajduczki, Vincent Dussupt, Bonnie Slike, Letzibeth Mendez-Rivera, Annika Schmid, Erin Kavusak, Mekhala Rao, Gabriel Smith, Jessica Frey, Alicea Sims, Lindsay Wieczorek, Victoria Polonis, Shelly J. Krebs, Julie A. Ake, Sandhya Vasan, Diane L. Bolton, M. Gordon Joyce, Samantha Townsley, Morgane Rolland
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract An effective HIV-1 vaccine must elicit broadly neutralizing antibodies (bnAbs) against highly diverse Envelope glycoproteins (Env). Since Env with the longest hypervariable (HV) loops is more resistant to the cognate bnAbs than Env with shor
Externí odkaz:
https://doaj.org/article/4aed98c53021448ba001318c61974fb7
Autor:
Dennis L. Murray, Charles J. Krebs
Publikováno v:
Frontiers in Ecology and Evolution, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/754c590103a3446c932c44c879775175
Autor:
Hannah A. Miller, Jenilee Gobin, Melanie R. Boudreau, Liam G. Horne, Lee E. Scholl, Jacob L. Seguin, Samuel Sonnega, Charles J. Krebs, Rudy Boonstra, Alice J. Kenney, Thomas S. Jung, Stan Boutin, Dennis L. Murray
Publikováno v:
Frontiers in Ecology and Evolution, Vol 12 (2024)
Animals exhibit dynamic movement and activity in response to environmental variation including changes in reproductive opportunities, predation risk, or food availability. Yet, it remains unclear which factors are primary in affecting animal movement
Externí odkaz:
https://doaj.org/article/e3eef6d954504faebf3730dfc1847679
Autor:
In-Jeong Kim, Olga Gonzalez, Michael P. Tighe, Paula A. Lanthier, Madeline J. Clark, Kelsey L. Travis, Timothy C. Low-Beer, Kathleen G. Lanzer, Derek T. Bernacki, Frank M. Szaba, Rafael A. De La Barrera, Vincent Dussupt, Letzibeth Mendez-Rivera, Shelly J. Krebs, Corinna N. Ross, Stephanie D. Mdaki, Kathleen M. Brasky, Donna Layne-Colon, Suzette D. Tardif, Stephen J. Thomas, Kayvon Modjarrad, Marcia A. Blackman, Jean L. Patterson
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-9 (2024)
Abstract Zika virus (ZIKV) infection during pregnancy poses significant threats to maternal and fetal health, leading to intrauterine fetal demise and severe developmental malformations that constitute congenital Zika syndrome (CZS). As such, the dev
Externí odkaz:
https://doaj.org/article/b9add105d8704c0d82513d7770efca3f
Autor:
In-Jeong Kim, Michael P. Tighe, Paula A. Lanthier, Madeline J. Clark, Rafael A. De La Barrera, Vincent Dussupt, Letzibeth Mendez-Rivera, Shelly J. Krebs, Kelsey L. Travis, Timothy C. Low-Beer, Tres S. Cookenham, Kathleen G. Lanzer, Derek T. Bernacki, Frank M. Szaba, Amanda A. Schneck, Jerrold Ward, Stephen J. Thomas, Kayvon Modjarrad, Marcia A. Blackman
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Zika virus (ZIKV) is a significant threat to pregnant women and their fetuses as it can cause severe birth defects and congenital neurodevelopmental disorders, referred to as congenital Zika syndrome (CZS). Thus, a safe and effective ZIKV va
Externí odkaz:
https://doaj.org/article/dbc43c97314347e0a2f015da2e56b4ce
Autor:
Rajeshwer S. Sankhala, Kerri G. Lal, Jaime L. Jensen, Vincent Dussupt, Letzibeth Mendez-Rivera, Hongjun Bai, Lindsay Wieczorek, Sandra V. Mayer, Michelle Zemil, Danielle A. Wagner, Samantha M. Townsley, Agnes Hajduczki, William C. Chang, Wei-Hung Chen, Gina C. Donofrio, Ningbo Jian, Hannah A. D. King, Cynthia G. Lorang, Elizabeth J. Martinez, Phyllis A. Rees, Caroline E. Peterson, Fabian Schmidt, Tricia J. Hart, Debra K. Duso, Lawrence W. Kummer, Sean P. Casey, Jazmean K. Williams, Shruthi Kannan, Bonnie M. Slike, Lauren Smith, Isabella Swafford, Paul V. Thomas, Ursula Tran, Jeffrey R. Currier, Diane L. Bolton, Edgar Davidson, Benjamin J. Doranz, Theodora Hatziioannou, Paul D. Bieniasz, Dominic Paquin-Proulx, William W. Reiley, Morgane Rolland, Nancy J. Sullivan, Sandhya Vasan, Natalie D. Collins, Kayvon Modjarrad, Gregory D. Gromowski, Victoria R. Polonis, Nelson L. Michael, Shelly J. Krebs, M. Gordon Joyce
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The repeat emergence of SARS-CoV-2 variants of concern (VoC) with decreased susceptibility to vaccine-elicited antibodies highlights the need to develop next-generation vaccine candidates that confer broad protection. Here we describe the an
Externí odkaz:
https://doaj.org/article/61dc74f1c5d84f64ac1178c032cab9f4
Autor:
Thembi Mdluli, Bonnie M. Slike, Daniel J. Curtis, Zhanna Shubin, Ursula Tran, Yifan Li, Vincent Dussupt, Letzibeth Mendez-Rivera, Suteeraporn Pinyakorn, Daniel J. Stieh, Frank L. Tomaka, Hanneke Schuitemaker, Maria G. Pau, Donn J. Colby, Eugène Kroon, Carlo Sacdalan, Mark de Souza, Nittaya Phanupak, Denise C. Hsu, Jintanat Ananworanich, Julie A. Ake, Lydie Trautmann, Sandhya Vasan, Merlin L. Robb, Shelly J. Krebs, Dominic Paquin-Proulx, Morgane Rolland
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114344- (2024)
Summary: A heterologous Ad26/MVA vaccine was given prior to an analytic treatment interruption (ATI) in people living with HIV-1 (mainly CRF01_AE) who initiated antiretroviral treatment (ART) during acute HIV-1. We investigate the impact of Ad26/MVA
Externí odkaz:
https://doaj.org/article/2a53194be3584d4cb1d89d2981acfbb5
Autor:
Lindsay Wieczorek, Eric Sanders-Buell, Michelle Zemil, Eric Lewitus, Erin Kavusak, Jonah Heller, Sebastian Molnar, Mekhala Rao, Gabriel Smith, Meera Bose, Amy Nguyen, Adwitiya Dhungana, Katherine Okada, Kelly Parisi, Daniel Silas, Bonnie Slike, Anuradha Ganesan, Jason Okulicz, Tahaniyat Lalani, Brian K Agan, Trevor A Crowell, Janice Darden, Morgane Rolland, Sandhya Vasan, Julie Ake, Shelly J Krebs, Sheila Peel, Sodsai Tovanabutra, Victoria R Polonis
Publikováno v:
PLoS Pathogens, Vol 19, Iss 12, p e1011780 (2023)
Subtype B HIV-1 has been the primary driver of the HIV-1 epidemic in the United States (U.S.) for over forty years and is also a prominent subtype in the Americas, Europe, Australia, the Middle East and North Africa. In this study, the neutralization
Externí odkaz:
https://doaj.org/article/81e83870173c4f2faaeff5746df525aa
Autor:
Wei-Hung Chen, Agnes Hajduczki, Elizabeth J. Martinez, Hongjun Bai, Hanover Matz, Thomas M. Hill, Eric Lewitus, William C. Chang, Layla Dawit, Caroline E. Peterson, Phyllis A. Rees, Adelola B. Ajayi, Emily S. Golub, Isabella Swafford, Vincent Dussupt, Sapna David, Sandra V. Mayer, Sandrine Soman, Caitlin Kuklis, Courtney Corbitt, Jocelyn King, Misook Choe, Rajeshwer S. Sankhala, Paul V. Thomas, Michelle Zemil, Lindsay Wieczorek, Tricia Hart, Debora Duso, Larry Kummer, Lianying Yan, Spencer L. Sterling, Eric D. Laing, Christopher C. Broder, Jazmean K. Williams, Edgar Davidson, Benjamin J. Doranz, Shelly J. Krebs, Victoria R. Polonis, Dominic Paquin-Proulx, Morgane Rolland, William W. Reiley, Gregory D. Gromowski, Kayvon Modjarrad, Helen Dooley, M. Gordon Joyce
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
SARS-CoV-2 variants of concern continue to emerge, reducing vaccine efficacy and limiting therapeutic options. Here, Chen and colleagues describe the identification and design of shark nanobodies with pansarbecovirus activity.
Externí odkaz:
https://doaj.org/article/898fe823bbf4468ea5527a2d0a41fa28