Zobrazeno 1 - 10
of 221
pro vyhledávání: '"J Kraicer"'
Publikováno v:
The Journal of physiology. 441
1. Somatotrophs from enzymatically dispersed anterior pituitary glands of rats, enriched to greater than 94% purity by density gradient centrifugation, were studied within 16 h of isolation using patch clamp recording methods in the conventional whol
Publikováno v:
Molecular and cellular endocrinology. 79(1-3)
The purpose of this study was to investigate the involvement of protein kinase C in growth hormone-releasing factor (GRF) action by directly measuring the effect of GRF on protein kinase C activity in purified male rat somatotrophs. Somatotrophs were
Publikováno v:
Canadian journal of physiology and pharmacology. 69(2)
The purpose of this study was to characterize the biological activity of the synthetic rat growth hormone releasing factor analogue rGRF(1–29)NH2 and to compare its action on growth hormone (GH) release to that of authentic rGRF(1–43)OH. We first
Publikováno v:
Endocrinology. 128(1)
GH-releasing factor (GRF)-stimulated GH release is dependent on a biphasic increase in free intracellular Ca2+ concentration [( Ca2+]i), resulting from an influx of Ca2+ into somatotrophs, while the inhibitory action of somatostatin (SRIF) on basal a
Publikováno v:
Endocrinology. 128(1)
This study was carried out to investigate the role of free intracellular Ca2+ ([Ca2+]i) in the action of GH-releasing factor (GRF) by determining whether GRF causes and increase in [Ca2+]i and whether this increase results from changes in Ca2+ influx
Publikováno v:
Endocrinology. 128(1)
This study was carried out to investigate the role of Ca2+ in the somatostatin (SRIF)-induced inhibition of GH release. We examined the effect of SRIF on basal and GH-releasing factor (GRF)-induced increases in Ca2+ influx and free intracellular Ca2+
Publikováno v:
Molecular and cellular endocrinology. 72(3)
We studied the role of the phosphatidylinositol system in the action of growth hormone-releasing factor (GRF). We asked whether GRF stimulates the activity of phospholipase C by determining GRF-induced changes in 32P labeling of the individual phosph
Publikováno v:
Endocrinology. 122:1511-1514
GH feeds back at the level of the central nervous system to alter the release of somatostatin and GRF, resulting in altered GH release. The purpose of this study was to see whether the concentration of GH, impinging directly on the somatotrophs of th
Autor:
A.E. Jimenez, G. Beraud, D.W. Lywood, M.J. Bragdon, J. Kraicer, J. L. Voogt, L. Caligaris, H.W. Burden, P.M. Packman, S. Taleisnik, I.E. Lawrence, R.L. Boshans, L. A. Carr
Publikováno v:
Neuroendocrinology. 23:I-IV
Publikováno v:
Neuroendocrinology. 23:352-367
Pars intermedia (PI) ACTH and melanocyte-stimulating hormone (MSH) content and pars distalis (PD) ACTH concentration were measured following 3 experimentally induced 'perturbations'. The feedback-induced increase in ACTH release following adrenalecto