Zobrazeno 1 - 10
of 238
pro vyhledávání: '"J Kolls"'
Autor:
Brad J. Kolls, Keith W. Muir, Sean I. Savitz, Lawrence R. Wechsler, Julie G. Pilitsis, Scott Rahimi, Richard L. Beckman, Vincent Holmes, Peng R. Chen, David S. Albers, Daniel T. Laskowitz
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Recruitment of participants is the greatest risk to completion of most clinical trials, with 20–40% of trials failing to reach the targeted enrollment. This is particularly true of trials of central nervous system (CNS) therapie
Externí odkaz:
https://doaj.org/article/c3732c3a4d014d00a0a506ffb4de9cef
Autor:
Zhuoran Wang, Qiang Li, Brad J. Kolls, Brian Mace, Shu Yu, Xuan Li, Wei Liu, Eduardo Chaparro, Yuntian Shen, Lihong Dang, Ángela del Águila, Joshua D. Bernstock, Kory R. Johnson, Junjie Yao, William C. Wetsel, Scott D. Moore, Dennis A. Turner, Wei Yang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
XBP1s is a key effector of the unfolded protein response. Neuron-specific overexpression of Xbp1s in the brain leads to impaired GABAergic signaling and recurrent spontaneous seizures in mice.
Externí odkaz:
https://doaj.org/article/41145015ec054931bd78b62feab0a1cb
Autor:
Miaomiao Xue, Shuya Li, Mingzhi Xu, Li Yan, Daniel T. Laskowitz, Brad J. Kolls, Gang Chen, Xiaohong Qian, Yongjun Wang, Haifeng Song, Yi Wang
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 1, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/ebb9cc350f7245bc8a4af3c2f118f358
Publikováno v:
Journal of Neuroanaesthesiology and Critical Care, Vol 06, Iss 02, Pp 140-144 (2019)
This review discusses cerebral venous thrombosis (CVT), including diagnosis and treatment strategies, a rare class of stroke that, if unrecognized or untreated, can have devastating effects. Thrombosis of one or many cerebral veins leads to propagati
Externí odkaz:
https://doaj.org/article/48c29cbbe1244a8cb00d35abd9b5bfb0
Autor:
Brad J. Kolls, Brian E. Mace
Publikováno v:
Informatics in Medicine Unlocked, Vol 23, Iss , Pp 100548- (2021)
Despite evidence to suggest that as many as 30% of hospitalized patients with altered mental status may be having subclinical seizures for which treatment may improve patient outcomes, the adoption of continuous video electroencephalography (EEG) mon
Externí odkaz:
https://doaj.org/article/dbf53bbed2bb485fb809cef11f361c77
Autor:
DaiWai M. Olson, Keith Dombrowski, Christopher Lynch, Brian Mace, Rahul Sinha, Stephen Spainhour, Michael Naglich, Kristina Riemen, Brad J. Kolls
Publikováno v:
Informatics in Medicine Unlocked, Vol 20, Iss , Pp 100379- (2020)
This study aimed to investigate how intermittent ICU data documented by nursing in the electronic medical record (EMR) corresponds to that obtained from continuous data acquisition (CDA) and the differences in perception by medical providers. Both de
Externí odkaz:
https://doaj.org/article/f634d7f9d55a4926a0cff4b62838ad2f
Autor:
Viviana Cantillana, Maureen Maughan, David W Van Wyck, Daniel T. Laskowitz, Bradley J. Kolls, Haiyan Wang
Publikováno v:
Experimental Brain Research. 240:2413-2423
Introduction: Traumatic brain injury (TBI) has become the signature wound of recent military operations and training over the past two decades. A treatment that would protect against secondary brain injury in TBI and improve the long-term functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4337ad01ae7307264374118aa2c29e
https://doi.org/10.1007/s00221-022-06417-4
https://doi.org/10.1007/s00221-022-06417-4
Autor:
Pranav I. Warman, Andreas Seas, Nihal Satyadev, Syed M. Adil, Brad J. Kolls, Michael M. Haglund, Timothy W. Dunn, Anthony T. Fuller
Publikováno v:
Neurosurgery. 90:605-612
Machine learning (ML) holds promise as a tool to guide clinical decision making by predicting in-hospital mortality for patients with traumatic brain injury (TBI). Previous models such as the international mission for prognosis and clinical trials in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5a7aa2f6a2ee75f7a367f9bc7de584
https://doi.org/10.1227/neu.0000000000001898
https://doi.org/10.1227/neu.0000000000001898
Autor:
Leo Ungar, Robert M. Clare, Fatima Rodriguez, Bradley J. Kolls, Paul W. Armstrong, Philip Aylward, Claes Held, David J. Moliterno, John Strony, Frans Van de Werf, Lars Wallentin, Harvey D. White, Pierluigi Tricoci, Robert A. Harrington, Kenneth W. Mahaffey, Chiara Melloni
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 24 (2018)
Background Vorapaxar, a protease‐activated receptor‐1 antagonist, is approved for secondary prevention of cardiovascular events but is associated with increased intracranial hemorrhage. Methods and Results TRACER (Thrombin Receptor Antagonist for
Externí odkaz:
https://doaj.org/article/ddd00c1d3d304d07b3f96b5f6ed6633f
Autor:
Charis A Spears, Timothy W. Dunn, Michael M. Haglund, Michael E Muhumza, Anthony T. Fuller, Brad J. Kolls, Syed M Adil
Publikováno v:
Journal of Neurosurgery. 135:1569-1578
OBJECTIVE The purpose of this study was to investigate whether neurosurgical intervention for traumatic brain injury (TBI) is associated with reduced risks of death and clinical deterioration in a low-income country with a relatively high neurosurgic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b253cd7a1ad7948d89b171f32c16b990
https://doi.org/10.3171/2020.9.jns201828
https://doi.org/10.3171/2020.9.jns201828