Zobrazeno 1 - 10
of 395
pro vyhledávání: '"J Kingsbury"'
Autor:
Hermine I Brunner, Grant S Schulert, Alyssa Sproles, Sherry Thornton, Gabriel Vega Cornejo, Jordi Antón, Ruben Cuttica, Michael Henrickson, Ivan Foeldvari, Daniel J Kingsbury, Margarita Askelson, Jinqi Liu, Sumanta Mukherjee, Robert L Wong, Daniel J Lovell, Alberto Martini, Nicolino Ruperto, Alexei A Grom, on behalf of the Pediatric Rheumatology Collaborative Study Group (PRCSG) and the Paediatric Rheumatology International Trials Organisation (PRINTO)
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-12 (2024)
Abstract Background Juvenile idiopathic arthritis (JIA) comprises a heterogeneous group of conditions that can cause marked disability and diminished quality of life. Data on predictors of clinical response are insufficient to guide selection of the
Externí odkaz:
https://doaj.org/article/cacec7190d1a47c785f6a18258e0af8f
Autor:
Hermine I Brunner, Grant S Schulert, Alyssa Sproles, Sherry Thornton, Gabriel Vega Cornejo, Jordi Antón, Ruben Cuttica, Michael Henrickson, Ivan Foeldvari, Daniel J Kingsbury, Margarita Askelson, Jinqi Liu, Sumanta Mukherjee, Robert L Wong, Daniel J Lovell, Alberto Martini, Nicolino Ruperto, Alexei A Grom, on behalf of the Pediatric Rheumatology Collaborative Study Group (PRCSG) and the Paediatric Rheumatology International Trials Organisation (PRINTO)
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/93046e6ed6464876be47a145987e012f
Autor:
Sang W. Hyun, Chiguang Feng, Anguo Liu, Erik P. Lillehoj, Rossana Trotta, Tami J. Kingsbury, Antonino Passaniti, Katerina N. Lugkey, Sitara Chauhan, John F. Cipollo, Irina G. Luzina, Sergei P. Atamas, Alan S. Cross, Simeon E. Goldblum
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-23 (2022)
Abstract To gain insight into sialic acid biology and sialidase/neuraminidase (NEU) expression in mature human neutrophil (PMN)s, we studied NEU activity and expression in PMNs and the HL60 promyelocytic leukemic cell line, and changes that might occ
Externí odkaz:
https://doaj.org/article/289ac30cc0a342a584ab79a26dfc59e5
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 77, Iss 4, Pp 341-345 (2021)
The crystal structures of three intermediate compounds in the synthesis of 8-bromo-2,3,4,5-tetrahydro-1,3,3-trimethyldipyrrin are reported; 4-bromo-2-formyl-1-tosyl-1H-pyrrole, C12H10BrNO3S, (E)-4-bromo-2-(2-nitrovinyl)-1-tosyl-1H-pyrrole, C13H11BrN2
Externí odkaz:
https://doaj.org/article/37bdee5425a44a03ad4f4a5a10fd600c
Autor:
Christopher J. Kingsbury, Keith J. Flanagan, Marc Kielmann, Brendan Twamley, Mathias O. Senge
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 76, Iss 2, Pp 214-220 (2020)
The crystal structures of the title compounds, two solvates (CHCl3 and THF) of a symmetric and highly substituted porphyrin, C44H2Br8F20N4 or OBrTPFPP, are described. These structures each feature a non-planar porphyrin ring, exhibiting a similar con
Externí odkaz:
https://doaj.org/article/f8a62f49836f42d49c339363b72a53c4
Autor:
Anna J. Dellomo, Rachel Abbotts, Christian L. Eberly, Mariusz Karbowski, Maria R. Baer, Tami J. Kingsbury, Feyruz V. Rassool
Publikováno v:
Translational Oncology, Vol 15, Iss 1, Pp 101283- (2022)
Signal transducer and activator of transcription 5 (STAT5) signaling plays a pathogenic role in both hematologic malignancies and solid tumors. In acute myeloid leukemia (AML), internal tandem duplications of fms-like tyrosine kinase 3 (FLT3-ITD) con
Externí odkaz:
https://doaj.org/article/1a37956d049b40a797eb0d03b6d03d1b
Publikováno v:
Molecules, Vol 27, Iss 20, p 7060 (2022)
Coordinating the spatial arrangement of electroactive partners is crucial to designable molecular electronics and photonics. Porphyrins are ubiquitous reaction centers in nature; synthetic porphyrins, in the crystallographic solid state, are often co
Externí odkaz:
https://doaj.org/article/52dfaf69a3c0426abeba9a378982268f
Autor:
Hermine I. Brunner, Lisa G. Rider, Daniel J. Kingsbury, Dominic Co, Rayfel Schneider, Ellen Goldmuntz, Karen B. Onel, Edward H. Giannini, Daniel J. Lovell, for the PRCSG Advisory Council
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 16, Iss 1, Pp 1-9 (2018)
Abstract Importance Specialized research networks are essential to achieve drug approvals for rare pediatric diseases. Such networks help realize the potential of global legislation enacted upon the recognition that most children are treated with dru
Externí odkaz:
https://doaj.org/article/a0d3636a895d43daa8f1fae3d1c9043b
Autor:
Nicolino Ruperto, Hermine I. Brunner, Zbigniew Zuber, Nikolay Tzaribachev, Daniel J. Kingsbury, Ivan Foeldvari, Gerd Horneff, Elzbieta Smolewska, Richard K. Vehe, Anasuya Hazra, Rong Wang, Charles A. Mebus, Christine Alvey, Manisha Lamba, Sriram Krishnaswami, Thomas C. Stock, Min Wang, Ricardo Suehiro, Alberto Martini, Daniel J. Lovell, for the Pediatric Rheumatology International Trials Organization (PRINTO), the Pediatric Rheumatology Collaborative Study Group (PRCSG)
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 15, Iss 1, Pp 1-10 (2017)
Abstract Background Juvenile idiopathic arthritis (JIA) is the most common pediatric rheumatic disease and a leading cause of childhood disability. The objective of this study was to characterize the PK, safety, and taste acceptability of tofacitinib
Externí odkaz:
https://doaj.org/article/8b41efdbbeb34a4f96be87df88800a71
Autor:
Robert A. Brown, Antanina Voit, Manasa P. Srikanth, Julia A. Thayer, Tami J. Kingsbury, Marlene A. Jacobson, Marta M. Lipinski, Ricardo A. Feldman, Ola Awad
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 10 (2019)
Bi-allelic GBA1 mutations cause Gaucher's disease (GD), the most common lysosomal storage disorder. Neuronopathic manifestations in GD include neurodegeneration, which can be severe and rapidly progressive. GBA1 mutations are also the most frequent g
Externí odkaz:
https://doaj.org/article/071ad8f2001a470988d9369dd1d74923