Zobrazeno 1 - 10
of 34
pro vyhledávání: '"J Keith Vass"'
Autor:
Clare M Lee, Manikhandan A V Mudaliar, D R Haggart, C Roland Wolf, Gino Miele, J Keith Vass, Desmond J Higham, Daniel Crowther
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e48238 (2012)
Non-negative matrix factorization is a useful tool for reducing the dimension of large datasets. This work considers simultaneous non-negative matrix factorization of multiple sources of data. In particular, we perform the first study that involves m
Externí odkaz:
https://doaj.org/article/ffffc64c28354e36bb6fc5ddaf18e154
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18634 (2011)
Biomarker identification, using network methods, depends on finding regular co-expression patterns; the overall connectivity is of greater importance than any single relationship. A second requirement is a simple algorithm for ranking patients on how
Externí odkaz:
https://doaj.org/article/508d2da920da430a866795e8512f3258
Autor:
Paul R. Harrison, E. Ken Parkinson, D. Gordon MacDonald, Pawel Herzyk, Des J. Higham, Gabriela Kalna, J. Keith Vass, Paul J.H. Drake, Janis Fleming, Johanna K. Thurlow, Keith D. Hunter
Most head and neck squamous cell carcinoma (HNSCC) patients present with late-stage cancers, which are difficult to treat. Therefore, early diagnosis of high-risk premalignant lesions and incipient cancers is important. HNSCC is currently perceived a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3e2cd64f5532c48cdc0b57c738b751
https://doi.org/10.1158/0008-5472.c.6494696.v1
https://doi.org/10.1158/0008-5472.c.6494696.v1
Autor:
Paul R. Harrison, E. Ken Parkinson, D. Gordon MacDonald, Pawel Herzyk, Des J. Higham, Gabriela Kalna, J. Keith Vass, Paul J.H. Drake, Janis Fleming, Johanna K. Thurlow, Keith D. Hunter
Supplementary Figure S1, Tables S1-S5 from Divergent Routes to Oral Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3f0a3b617d9146fe4c84021be6f230
https://doi.org/10.1158/0008-5472.22365431
https://doi.org/10.1158/0008-5472.22365431
Publikováno v:
Briefings in Functional Genomics. 11:457-468
Spectral methods, which use information relating to eigenvectors, singular vectors and generalized singular vectors, help us to visualize and summarize sets of pairwise interactions. In this work, we motivate and discuss the use of spectral methods b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622458b991b4aff9a7e89b96221d86d8
https://doi.org/10.1093/bfgp/els040
https://doi.org/10.1093/bfgp/els040
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1813(1):60-72
Transcriptional activity of hypoxia-induced factor 1 (HIF1) – a heterodimer of HIF1α and ARNT (HIF1β) – is essential for cellular adaptation to environmental stress and plays an important role in skin development, wound healing, tumorigenesis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f4f424cb7055ee5d6d0854066dcd7d
Publikováno v:
International Journal of Computer Mathematics. 85:475-485
Eigenvectors and, more generally, singular vectors, have proved to be useful tools for data mining and dimension reduction. Spectral clustering and reordering algorithms have been designed and implemented in many disciplines, and they can be motivate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcee0d64327f4e3f4408c8bf208189e5
https://doi.org/10.1080/00207160701210158
https://doi.org/10.1080/00207160701210158
Autor:
Laura Kennedy, J. Keith Vass, D. Ross Haggart, Steve Moore, Michael E. Burczynski, Dan Crowther, Gino Miele
Publikováno v:
Biomarker Insights, Vol 3, Pp 403-417 (2008)
Peripheral blood as a surrogate tissue for transcriptome profiling holds great promise for the discovery of diagnostic and prognostic disease biomarkers, particularly when target tissues of disease are not readily available. To maximize the reliabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::86a8f5a739b9d79d3ef86a3a8b5c7148
http://www.la-press.com/article.php?article_id=963
http://www.la-press.com/article.php?article_id=963
Autor:
Eric O'Neill, David Romano, Lucia Kucerova, Walter Kolch, J. Keith Vass, Karen Yee, David Matallanas, Katrin Meissl, Daniela Piazzolla, Manuela Baccarini
Publikováno v:
Molecular Cell. 27(6):962-975
RASSF1A is a tumor suppressor gene that is epigenetically silenced in a wide variety of sporadic human malignancies. Expression of alternative RASSF1 isoforms cannot substitute for RASSF1A-promoted cell-cycle arrest and apoptosis. Apoptosis can be dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f402b0b2506f620284f0510a0b3cc8c
Publikováno v:
Stem Cells. 25:3111-3120
Quiescent and dividing hemopoietic stem cells (HSC) display marked differences in their ability to move between the peripheral circulation and the bone marrow. Specifically, long-term engraftment potential predominantly resides in the quiescent HSC s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311398f321b1d49a053c779a554002ae
https://doi.org/10.1634/stemcells.2007-0250
https://doi.org/10.1634/stemcells.2007-0250