Zobrazeno 1 - 10
of 24
pro vyhledávání: '"J K Kuppen P"'
Autor:
Ehsan Gharib, Leili Rejali, Moein Piroozkhah, Elham Zonoobi, Parinaz Nasri Nasrabadi, Zahra Arabsorkhi, Kaveh Baghdar, Elahe Shams, Amir Sadeghi, Peter J. K. Kuppen, Zahra Salehi, Ehsan Nazemalhosseini-Mojarad
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Despite advances in treatment strategies, colorectal cancer (CRC) continues to cause significant morbidity and mortality, with mounting evidence a close link between immune system dysfunctions issued. Interleukin-2 receptor gamma (IL-2RG) pl
Externí odkaz:
https://doaj.org/article/941c88d9fac5417fbc92703cafc4e8a3
Autor:
Hehuan Zhu, Jessica Roelands, Eiman I. Ahmed, Imke Stouten, Rachel Hoorntje, Ronald L. P. van Vlierberghe, Marieke E. Ijsselsteijn, Xin Lei, Noel F. C. C. de Miranda, Rob A. E. M. Tollenaar, Alexander L. Vahrmeijer, Davide Bedognetti, Wouter R. L. Hendrickx, Peter J. K. Kuppen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundColon cancer is a heterogeneous disease and consists of various molecular subtypes. Despite advances in high-throughput expression profiling, limitations remain in predicting clinical outcome and assigning specific treatment to individual c
Externí odkaz:
https://doaj.org/article/aa1aea9886e3453dbf21cf7328104ccf
Autor:
Xi Zhang, Aparna Gunda, Elma Meershoek-Klein Kranenbarg, Gerrit-Jan Liefers, Badada Ananthamurthy Savitha, Payal Shrivastava, Chandra Prakash Vijay Kumar Serkad, Taranjot Kaur, Mallikarjuna Siraganahalli Eshwaraiah, Rob A. E. M. Tollenaar, Cornelis J. H. van de Velde, Caroline M. J. Seynaeve, Manjiri Bakre, Peter J. K. Kuppen
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-11 (2023)
Abstract Background Hormone receptor (HR)-positive, HER2/neu-negative breast cancers have a sustained risk of recurrence up to 20 years from diagnosis. TEAM (Tamoxifen, Exemestane Adjuvant Multinational) is a large, multi-country, phase III trial tha
Externí odkaz:
https://doaj.org/article/3d99b753ff134f63ac6057c295814442
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/9e4dd9355e9340068281c29f8c7ef92e
Autor:
Jessica Roelands, Raghvendra Mall, Hossam Almeer, Remy Thomas, Mahmoud G. Mohamed, Shahinaz Bedri, Salha Bujassoum Al-Bader, Kulsoom Junejo, Elad Ziv, Rosalyn W. Sayaman, Peter J. K. Kuppen, Davide Bedognetti, Wouter Hendrickx, Julie Decock
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract Breast cancer largely dominates the global cancer burden statistics; however, there are striking disparities in mortality rates across countries. While socioeconomic factors contribute to population-based differences in mortality, they do no
Externí odkaz:
https://doaj.org/article/b9ef27825e2f4d69a5e91d3295cb1212
Autor:
Rayna J. S. Anijs, El Houari Laghmani, Betül Ünlü, Szymon M. Kiełbasa, Hailiang Mei, Suzanne C. Cannegieter, Frederikus A. Klok, Peter J. K. Kuppen, Henri H. Versteeg, Jeroen T. Buijs
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 5, Pp n/a-n/a (2022)
Abstract Background Colorectal cancer patients have an increased risk of developing venous thromboembolism (VTE), resulting in increased morbidity and mortality. Because the exact mechanism is yet unknown, risk prediction is still challenging; theref
Externí odkaz:
https://doaj.org/article/2c0b1feb2ee14dffae9ea1e831e36f88
Autor:
V. M. Baart, R. D. Houvast, L. F. de Geus-Oei, P. H. A. Quax, P. J. K. Kuppen, A. L. Vahrmeijer, C. F. M. Sier
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-18 (2020)
Abstract The urokinase plasminogen activator receptor (uPAR) plays a multifaceted role in almost any process where migration of cells and tissue-remodeling is involved such as inflammation, but also in diseases as arthritis and cancer. Normally, uPAR
Externí odkaz:
https://doaj.org/article/51d06986b4094a06a263c3b2b762cb87
Autor:
Wilko Weichert, Lei Cai, Soldano Ferrone, Peter J K Kuppen, Lindy G Durrant, Theodoros Michelakos, Filippos Kontos, Tomohiro Kurokawa, Ananthan Sadagopan, Danielle Krijgsman, Cristina R Ferrone
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Purpose The association of human leucocyte antigen (HLA) class I expression levels with the clinical course of many malignancies reflects their crucial role in the recognition and elimination of malignant cells by cognate T cells and NK cells. In col
Externí odkaz:
https://doaj.org/article/e7b9bb0a184e4674bba2e19cb5b513a1
Autor:
Zeger Rijs, Esther Belt, Gijsbert M. Kalisvaart, Cornelis F. M. Sier, Peter J. K. Kuppen, Arjen H. G. Cleven, Alexander L. Vahrmeijer, Michiel A. J. van de Sande, Pieter B. A. A. van Driel
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 982 (2023)
Introduction: Myxofibrosarcoma (MFS) is the most common soft-tissue sarcoma subtype in elderly patients. Local recurrence (LR) remains a major concern as the lack of intraoperative guidance and an infiltrative growth pattern with long, slender tails
Externí odkaz:
https://doaj.org/article/55b072910c034b08ac7f404a9a600c1b
Autor:
Marcelo Sobral-Leite, Izhar Salomon, Mark Opdam, Dinja T. Kruger, Karin J. Beelen, Vincent van der Noort, Ronald L. P. van Vlierberghe, Erik J. Blok, Daniele Giardiello, Joyce Sanders, Koen Van de Vijver, Hugo M. Horlings, Peter J. K. Kuppen, Sabine C. Linn, Marjanka K. Schmidt, Marleen Kok
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-12 (2019)
Abstract Introduction The presence of tumor-infiltrating lymphocytes (TILs) is correlated with good prognosis and outcome after (immuno)therapy in triple-negative and HER2-positive breast cancer. However, the role of TILs in luminal breast cancer is
Externí odkaz:
https://doaj.org/article/5959f536479546c2a4aaf6e54c131c05