Výsledky vyhledávání

Estrogen receptor methylation is associated with improved survival in adult acute myeloid leukemia

Autor: Q, Li, K J, Kopecky, A, Mohan, C L, Willman, F R, Appelbaum, J K, Weick, J P, Issa

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 5(5)

Estrogen receptor methylation (ERM) is a frequent molecular alteration in adult acute myeloid leukemia (AML). In this study, we sought to determine the clinical characteristics and prognostic significance of ERM in AML. ERM was determined for 268 pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5907092c16ba524f94bf2d098bb37ced
https://pubmed.ncbi.nlm.nih.gov/10353741

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A randomized investigation of high-dose versus standard-dose cytosine arabinoside with daunorubicin in patients with previously untreated acute myeloid leukemia: a Southwest Oncology Group study

Autor: J K, Weick, K J, Kopecky, F R, Appelbaum, D R, Head, L L, Kingsbury, S P, Balcerzak, J N, Bickers, H E, Hynes, J L, Welborn, S R, Simon, M, Grever

Publikováno v: Blood. 88(8)

Interest in high-dose cytarabine (HDAC) for both induction and postremission therapy for acute myeloid leukemia (AML) prompted the Southwest Oncology Group (SWOG) to initiate a randomized trial comparing HDAC with standard-dose cytarabine (SDAC) for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9732cd51d9ba54877fe386e4c01c7ffb
https://pubmed.ncbi.nlm.nih.gov/8874180

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Correlation of multidrug resistance (MDR1) protein expression with functional dye/drug efflux in acute myeloid leukemia by multiparameter flow cytometry: identification of discordant MDR-/efflux+ and MDR1+/efflux- cases

Autor: C P, Leith, I M, Chen, K J, Kopecky, F R, Appelbaum, D R, Head, J E, Godwin, J K, Weick, C L, Willman

Publikováno v: Blood. 86(6)

Resistance to chemotherapy is a major factor limiting successful treatment of acute myeloid leukemia (AML); one of the best characterized drug resistance mechanisms is extrusion of drugs by the energy-dependent multidrug resistance (MDR1) transport p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::044df543a69d02d75ecf2a474d723b54
https://pubmed.ncbi.nlm.nih.gov/7545025

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A phase I trial of combination fludarabine monophosphate and chlorambucil in chronic lymphocytic leukemia: a Southwest Oncology Group study

Autor: L, Elias, D, Stock-Novack, D R, Head, M R, Grever, J K, Weick, R A, Chapman, J E, Godwin, E N, Metz, F R, Appelbaum

Publikováno v: Leukemia. 7(3)

Fludarabine monophosphate is a new antimetabolite with demonstrated activity in chronic lymphocytic leukemia (CLL). We have investigated the practicality of utilizing fludarabine in combination with chlorambucil in a disease-specific phase I trial. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::54320f1e777ea68b60babe5c291ab0d3
https://pubmed.ncbi.nlm.nih.gov/7680398

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Phase II trial of ifosfamide and cisplatin in the treatment of metastatic sarcomas: a Southwest Oncology Group study

Autor: G T, Budd, B, Metch, S A, Weiss, J K, Weick, C, Fabian, R L, Stephens, S P, Balcerzak

Publikováno v: Cancer chemotherapy and pharmacology. 31

The Southwest Oncology Group (SWOG) performed a phase II trial of a combination of ifosfamide/mesna/cisplatin in patients with metastatic soft-tissue sarcoma who had previously received one chemotherapeutic regimen. A total of 39 patients were regist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7c46b47dc92d3f0f51e88b8d6f06c5dc
https://pubmed.ncbi.nlm.nih.gov/8453701

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Precursor Langerhans cell histiocytosis. An unusual histiocytic proliferation in a patient with persistent non-Hodgkin lymphoma and terminal acute monocytic leukemia

Autor: G H, Segal, M V, Mesa, A J, Fishleder, M H, Stoler, J K, Weick, A E, Lichtin, R R, Tubbs

Publikováno v: Cancer. 70(2)

Langerhans cell precursors are considered to be identical to their mature counterparts except for the lack of Birbeck granules. Proliferations composed of such histiocytes appear to be uncommon.Standard immunophenotypic, molecular genetic, and DNA co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::62426f930b6822591d6afa0ea223c95f
https://pubmed.ncbi.nlm.nih.gov/1617604

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A Southwest Oncology Group phase II Trial of recombinant tumor necrosis factor in metastatic breast cancer

Autor: G T, Budd, S, Green, L H, Baker, E P, Hersh, J K, Weick, C K, Osborne

Publikováno v: Cancer. 68(8)

New approaches are needed in the treatment of advanced breast cancer. In vitro studies have shown that recombinant tumor necrosis factor (TNF) is a growth inhibitor for the MCF-7, ZR-75-1, and BT-20 human breast cancer cell lines. Based on these cons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f70019e387992d77a3d7cb21b8a223f1
https://pubmed.ncbi.nlm.nih.gov/1913510

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Finding an appropriate dose of fentanyl effervescent buccal tablets for relief of cancer-related breakthrough pain

Autor: J. K. Weick, John Messina, Russell K. Portenoy, L. Tremmel

Publikováno v: Journal of Clinical Oncology. 24:8564-8564

8564 Background: The recommended dose of a short-acting oral opioid used to treat cancer-related breakthrough pain (BTP) is 5%-15% of the equianalgesic around-the-clock (ATC) opioid dose used to control persistent pain; however, this dosing strategy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::65342808d79094b95b0c86bd9d0db5b8
https://doi.org/10.1200/jco.2006.24.18_suppl.8564

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