Výsledky vyhledávání - "J K, Wamsley"

Felbamate increases [3H]glycine binding in rat brain and sections of human postmortem brain

Autor: R T, McCabe, R D, Sofia, R T, Layer, K A, Leiner, R L, Faull, N, Narang, J K, Wamsley

Publikováno v: The Journal of pharmacology and experimental therapeutics. 286(2)

The anticonvulsant compound felbamate (2-phenyl-1,3-propanediol dicarbamate; FBM) appears to inhibit the function of the N-methyl-D-aspartate (NMDA) receptor complex through an interaction with the strychnine-insensitive glycine recognition site. Sin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::079a673d4ae26b2914be715346d98014
https://pubmed.ncbi.nlm.nih.gov/9694960

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Felbamate: interaction with glycine receptors in human cerebral cortex

Autor: J K, Wamsley, R D, Sofia, R L, Faull, N, Narang, T, Ary, X D, Gan, R T, McCabe

Publikováno v: Proceedings of the Western Pharmacology Society. 37

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3d13863d440ac822741536d276b21f50
https://pubmed.ncbi.nlm.nih.gov/7984680

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Effects on monoamine levels in rat CNS after chronic administration of cocaine

Autor: M E, Alburges, J K, Wamsley

Publikováno v: Investigacion clinica. 34(4)

We have previously reported time-dependent and dose-dependent changes in the rat dopaminergic receptor system following chronic administration of cocaine (upregulation of cocaine, D1, and DA-uptake sites). We have now evaluated the effects of chronic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0c043943aa5a4f55a74490a2117b8581
https://pubmed.ncbi.nlm.nih.gov/7516188

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GABA-benzodiazepine receptors

Autor: J K, Wamsley

Publikováno v: The American journal of psychiatry. 149(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9038a02430471a6f066ddf17f7fce44a
https://pubmed.ncbi.nlm.nih.gov/1702937

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[Chronic manganese poisoning: autoradiographic quantification of cholinergic muscarinic receptors in mouse brain]

Autor: G, Cano, E, Bonilla, F, Castro, M, Alburges, J K, Wamsley

Publikováno v: Investigacion clinica. 33(2)

Chronic administration of manganese chloride (5 mg Mn/kg body weight/day) during nine weeks, did not affect the [3H]-quinuclidinyl benzilate binding to muscarinic cholinergic receptors in mouse brain. The quantitation and anatomical distribution of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::72db17db9fbefca654bd84b6c68c1fb9
https://pubmed.ncbi.nlm.nih.gov/1457534

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[D-Pen2,4'-125I-Phe4,D-Pen5]enkephalin: a selective high affinity radioligand for delta opioid receptors with exceptional specific activity

Autor: R J, Knapp, S D, Sharma, G, Toth, M T, Duong, L, Fang, C L, Bogert, S J, Weber, M, Hunt, T P, Davis, J K, Wamsley

Publikováno v: The Journal of pharmacology and experimental therapeutics. 258(3)

[D-Pen2,4'-125I-Phe4,D-Pen5]enkephalin ([125I]DPDPE) is a highly selective radioligand for the delta opioid receptor with a specific activity (2200 Ci/mmol) that is over 50-fold greater than that of tritium-labeled DPDPE analogs. [125I]DPDPE binds to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a8057ce29d37dcabad5f94fddb7862db
https://pubmed.ncbi.nlm.nih.gov/1653834

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Reversal of nigrostriatal-lesion-induced receptor alterations by grafting of fetal mesencephalic dopaminergic neurons

Autor: J K, Wamsley, T M, Dawson, V L, Dawson, M A, Hunt, L J, Fisher, F H, Gage

Publikováno v: Advances in experimental medicine and biology. 287

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c7e4c67af79a33786ced14239e28a39b
https://pubmed.ncbi.nlm.nih.gov/1759609

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Selective, unilateral cortical infarction increases striatal muscarinic receptor binding: potential evidence for cortical modulation of intrastriatal cholinergic transmission

Autor: F, Filloux, T H, Liu, C Y, Hsu, M A, Hunt, J K, Wamsley

Publikováno v: Journal of chemical neuroanatomy. 3(2)

The effects of unilateral cortical infarction on subcortical (striatal) muscarinic receptors in rat brain were studied by means of in vitro receptor autoradiography using [3H]quinuclidinyl benzylate ([3H]QNB) and [3H]pirenzepine. The cortical lesions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::afeed15d69326a6bff331d9d1ef6d195
https://pubmed.ncbi.nlm.nih.gov/2340116

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Effect of MPTP on Dopamine D2 Receptors in the Aging Mouse Striatum

Autor: J. K. Wamsley, M. Gupta, M. Hunt

Publikováno v: Basic, Clinical, and Therapeutic Aspects of Alzheimer’s and Parkinson’s Diseases ISBN: 9781468458466

Recently, MPTP (1-methyl, 4-phenyl-1, 2, 3, 6-tetrahydropyridine) present as a contaminant in a synthetic heroin, produced a Parkinson-like disorder following intravenous administration and caused destruction of the nigrostriatal dopamine system in h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::388c50a40d6ba31f57c885d4005d55b2
https://doi.org/10.1007/978-1-4684-5844-2_118

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GABAA receptor subtypes: autoradiographic comparison of GABA, benzodiazepine, and convulsant binding sites in the rat central nervous system

Autor: R W, Olsen, R T, McCabe, J K, Wamsley

Publikováno v: Journal of chemical neuroanatomy. 3(1)

The regional distribution of radioactive ligand binding in rat brain for the different receptors of the gamma-aminobutyric acidA (GABAA)-benzodiazepine receptor/chloride channel complex was measured on tissue sections by autoradiography. Seven ligand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b9f0ec2cc596518ac34b581b78961d7e
https://pubmed.ncbi.nlm.nih.gov/2156526

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