Zobrazeno 1 - 5
of 5
pro vyhledávání: '"J K, Staley"'
Autor:
John W. Boja, Anita H. Lewin, Philip Abraham, J. K. Staley, Deborah C. Mash, Christopher D. Wyrick, Herbert H. Seltzman, Frank I. Carroll
Publikováno v:
Synapse. 21:364-372
The novel cocaine analog RTI-121[3β-(4-iodophenyl)tropane-2β-carboxylic acid isopropyl ester] was evaluated as a probe for the in vitro labeling and localization of the dopamine transporter in the human brain. Saturation binding experiments conduct
Autor:
J C, Soares, C H, van Dyck, P, Tan, S S, Zoghbi, P, Garg, R, Soufer, R M, Baldwin, M, Fujita, J K, Staley, X, Fu, L, Amici, J, Seibyl, R B, Innis
Publikováno v:
Psychiatry research. 106(2)
The test/retest reproducibility of brain measures of 5-HT2A receptors with positron emission tomography (PET) and [18F]deuteroaltanserin was examined in a group of eight healthy human subjects. PET measures of 5-HT2A receptors were obtained under an
Autor:
M, Fujita, J P, Seibyl, N P, Verhoeff, M, Ichise, R M, Baldwin, S S, Zoghbi, C, Burger, J K, Staley, N, Rajeevan, D S, Charney, R B, Innis
Publikováno v:
Synapse (New York, N.Y.). 34(4)
Quantitative SPECT measures of dopamine D(2) like receptors with [(123)I]epidepride is complicated by its high affinity and lipophilic metabolites. The purpose of this study was to use both parent (P) and lipophilic metabolites (M) as input functions
Publikováno v:
European journal of pharmacology. 338(2)
The vesamicol analogue, meta-[(125)I]iodobenzyltrozamicol [(+)-[(125)I]MIBT] was evaluated as a probe for the in vitro labeling of the vesicular acetylcholine transporter in primate brain. In the striatum, (+)-[(125)I]MIBT bound a single high-affinit
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 271(3)
Cocaine mediates its powerful reinforcement by binding to recognition sites on the dopamine (DA) transporter. The pharmacological identity of cocaine recognition sites and their relevance to dopamine transport function has remained unclear. Ligand bi