Zobrazeno 1 - 10
of 48
pro vyhledávání: '"J K, Pandit"'
Publikováno v:
Current Drug Delivery. 8:398-406
Extensive attempts to overcome problems related to solubility of drugs for maximizing bioavailability at targeted sites in the body have been made. The issue of drug solubility appears to attract the continued interest of pharmaceutical manufacturers
Publikováno v:
Current Drug Delivery. 8:172-193
Eye diseases can cause discomfort and anxiety in patients, with the ultimate fear of loss of vision and facial disfigurement. Many regions of the eye are relatively inaccessible to systemically administered drugs and, as a result, topical drug delive
Publikováno v:
CHEMICAL & PHARMACEUTICAL BULLETIN. 59:315-320
The aim of this work was to prepare chitosan nanoparticles loaded with antineoplastic drug Lomustine (LCNPs), by ionic-gelation method with homogenization. The nanoparticles were characterized for particle size, polydispersity index (PDI), surface mo
Publikováno v:
Journal of Biomedical Nanotechnology. 6:648-657
The objective of the present study is to develop a poly (D, L-lactic acid) (PLA) nano-carrier for topical ocular applications. PLA nanoparticles (PLA-NPs) with 5-fluorouracil were prepared using varying concentration and molecular weight of PLA to re
Publikováno v:
AAPS PharmSciTech. 11:294-303
An oral sustained release dosage form of cinnarizine HCl (CNZ) based on gastric floating matrix tablets was studied. The release of CNZ from different floating matrix formulations containing four viscosity grades of hydroxypropyl methylcellulose, sod
Publikováno v:
Current Drug Delivery. 6:291-296
Bilayered tablets of Divalproex sodium for once-a-day administration were prepared using a hydrophilic and hydrophobic polymer as release retarding agents. This technology was found to be more effective than a simple matrix tablet with a mixture of t
Publikováno v:
Journal of Controlled Release. 136:2-13
Various efforts in ocular drug delivery have been made to improve the bioavailability and to prolong the residence time of drugs applied topically onto the eye. The potential use of polymeric nanoparticles as drug carriers has led to the development
Autor:
J. Balasubramaniam, Deena Nath Mishra, Neelam Mittal, Romi Barat, A. Srinatha, D. N. Ridhurkar, J. K. Pandit
Publikováno v:
Drug Delivery. 13:365-373
Periodontal pocket inserts of niridazole (NZ) made with Resomer(R) (grades RG 503H and RG858, designated as RH and RG, respectively) were studied. Various formulation variables were evaluated to obtain a biodegradable delivery systems showing device
Autor:
R.J. Babu, J. K. Pandit
Publikováno v:
International Journal of Pharmaceutics. 288:325-334
A reservoir-type transdermal delivery system (TDS) of bupranolol (BPL) was designed and evaluated for different formulation variables like gel reservoirs (made with anionic and nonionic polymers), rate controlling membranes and penetration enhancers
Autor:
R.J. Babu, J. K. Pandit
Publikováno v:
International Journal of Pharmaceutics. 271:155-165
Bupranolol (BPL) is a potent beta-blocking agent, the extensive first-pass metabolism (90%) and rapid elimination half-life (1.5-2.0 h) of this drug make it well suited to be developed as a transdermal delivery system (TDS). Hydroxypropyl betaCD (HPb