Zobrazeno 1 - 10
of 21
pro vyhledávání: '"J K, Kolls"'
Autor:
M. Bryer-Ash, A. Martinez-Hernandez, Junfeng Wang, J. K. Kolls, D. Dietzen, W. W. Starks, A. T. Cheung
Publikováno v:
Diabetes, Obesity and Metabolism. 3:367-380
Aim: Protein tyrosine phosphatase-1B (PTP-1B) is an intracellular PTP known to dephosphorylate and inactivate upstream tyrosine phosphoproteins in the insulin signalling cascade. We and others reported increased abundance of catalytically impaired PT
Autor:
K C A M, Nabbe, P, Boross, A E M, Holthuysen, A W, Sloëtjes, J K, Kolls, S, Verbeek, P L E M, van Lent, W B, van Den Berg
Publikováno v:
Arthritis and rheumatism. 52(3)
It has previously been shown that the onset and the degree of joint inflammation during immune complex (IC)-mediated arthritis depend on Fcgamma receptor type III (FcgammaRIII). Local adenoviral overexpression of interferon-gamma (IFNgamma) in the kn
Autor:
P, Byrne, W, Huang, V M, Wallace, M K, Shean, Z, Zhang, Q, Zhong, C, Theodossiou, H, Blakesley, J K, Kolls, P, Schwarzenberger
Publikováno v:
BioTechniques. 32(2)
Marine experimental stem cell transplantations require the accurate discrimination and quantification of donor cells from host cells. A Y-chromosome-specific, quantitative real-time PCR (kinetic PCR) protocol for blood-derived DNA was developed. The
Autor:
J, Wang, A T, Cheung, J K, Kolls, W W, Starks, A, Martinez-Hernandez, D, Dietzen, M, Bryer-Ash
Publikováno v:
Diabetes, obesitymetabolism. 3(5)
Protein tyrosine phosphatase-1B (PTP-1B) is an intracellular PTP known to dephosphorylate and inactivate upstream tyrosine phosphoproteins in the insulin signalling cascade. We and others reported increased abundance of catalytically impaired PTP-1B
Publikováno v:
The Journal of biological chemistry. 276(27)
Two significant barriers limit the use of amphotropic retrovirus for human gene transfer protocols: 1) low transduction efficiency in cells with low receptor expression and 2) safety concerns originating from the risk of formation and propagation of
Publikováno v:
Seminars in respiratory infections. 16(1)
Respiratory infections remain a significant public health problem and are presently the 6th leading cause of death in the United States. Antibiotic-resistant organisms are encountered increasingly in both community-acquired and nosocomial infections.
Publikováno v:
Alcoholism, clinical and experimental research. 25(3)
Ethanol (EtOH) is known to alter host immune responses and cytokine production. Acute EtOH exposure can suppress tumor necrosis factor (TNF)-alpha production, which attenuates pulmonary defense against infection. Previous studies in our laboratory sh
Publikováno v:
Current opinion in molecular therapeutics. 1(1)
Malignant mesothelioma (MM) is a tumor of the pleura with an etiology that has been strongly linked to previous asbestos exposure. It is an almost universally fatal disease, regardless of tumor stage at the time of diagnosis. Current treatment modali
Publikováno v:
Alcoholism, clinical and experimental research. 24(4)
Interleukin (IL)-12 is a cytokine with protean effects against bacterial and intracellular pathogens. Induction of IL-12 at the time of infection has salient effects on elimination of various microbes. This work describes the effect of exposure to et
Autor:
J D, Hunt, E G, Robert, A W, Zieske, A P, Bautista, M, Bukara, D, Lei, J E, Shellito, S, Nelson, J K, Kolls, N, Skrepnik
Publikováno v:
Cancer. 88(2)
The role of the immune system in the surveillance of the body for cancer cells is well established. Human tumor cells do not survive in mice with intact immune systems, but they propagate in athymic nude mice. Presumably, the lack of a thymus gland a