Zobrazeno 1 - 10
of 34
pro vyhledávání: '"J K, Gwathmey"'
Autor:
J. K. Gwathmey, J. A. Paige
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 17:420-425
Gwathmey, J.K., Paige, J.A. Endothelin and vasoactive peptides: new cardiovascular mediators. J, vet. Pharmacol. Therap. 17,420–425. A newly discovered family of vasoactive peptides, endothelins, have strong inotropic and chronotropic effects on th
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 267:H100-H108
The effect of 2,3-butanedione monoxime (BDM) was investigated during metabolic inhibition (MI) in papillary muscles. MI caused a rapid decrease in developed force and an increase in resting force, along with a decrease in ATP and creatine phosphate (
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 265:H1704-H1711
Broad-Breasted White turkey poults exhibit a low incidence of dilated cardiomyopathy (DCM). Ejection fraction in DCM turkeys with moderate to severe dilatation was decreased from 67 +/- 5% (control, n = 20) to 42 +/- 4% (DCM, n = 12; P = 0.001). Mode
Publikováno v:
Cardiovascular Research. 27:199-203
Objective: Calcium transients in muscles from patients with end stage heart failure consist of two components (L1 and L2) at physiological extracellular calcium concentrations ([Ca2+]); the second component (L2) can appear in normal human myocardium
Autor:
J. K. Gwathmey, Roger J. Hajjar
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 259:H784-H795
In the presence of 1 microM ryanodine, muscles loaded with the calcium indicator aequorin were stimulated at 15-20 Hz to produce steady levels of force and intracellular Ca2+ concentrations [( Ca2+]i) at various extracellular Ca2+ concentration ([Ca2
Autor:
J A Pesaturo, J. K. Gwathmey
Publikováno v:
Circulation Research. 66:696-709
The mechanism of twitch prolongation of hypoxic myocardium after reoxygenation was studied before and after interventions that affect cellular cyclic nucleotide levels, subcellular calcium handling, or oxygen-derived free radical production/survival.
Publikováno v:
Developments in Cardiovascular Medicine ISBN: 9781461348658
Myocarditis in humans is often subclinical and difficult to recognize,1 limiting our full appreciation of the natural history and potential progression of the disease to chronic cardiomyopathy. Searching for a suitable animal model we studied the car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e6d94f02d563d823938e04c86b881b7
https://doi.org/10.1007/978-1-4419-9264-2_24
https://doi.org/10.1007/978-1-4419-9264-2_24
Publikováno v:
Cardiovascular drugs and therapy. 15(6)
We have shown that chronic treatment with carteolol, a non-selective beta-adrenergic receptor antagonist, improved left ventricular (LV) function and survival in an avian model of dilated cardiomyopathy (DCM). The aim of the present study was to comp
Publikováno v:
Cardiovascular drugs and therapy. 13(5)
We have previously demonstrated that turkey poults fed furazolidone (Fz) in high concentrations (700 ppm) develop dilated cardiomyopathy (DCM) which approximates the human condition [1-3]. We wanted to study the effects of a calcium channel blocker i
Publikováno v:
Alcoholism, clinical and experimental research. 23(10)
Excessive alcohol consumption is recognized as a common cause of left ventricular (LV) dysfunction. It is currently thought that 36% of all cases of dilated cardiomyopathy are due to excessive alcohol intake. Suitable animal models are needed to stud