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Smoking history and lung carcinoma: KRAS mutation is an early hit in lung adenocarcinoma development

Autor: F B, Thunnissen, C, Prinsen, B, Hol, M, Van der Drift, A, Vesin, C, Brambilla, L, Montuenga, J K, Field, Jacek, Niklinski

Publikováno v: Lung Cancer, 75, 2, pp. 156-60
Lung Cancer, 75(2), 156-160. Elsevier Ireland Ltd
Thunnissen, F B J M, Prinsen, C, Hol, B, van der Drift, M, Vesin, A, Brambilla, C, Montuenga, L & Field, J K 2012, ' Smoking history and lung carcinoma: KRAS mutation is an early hit in lung adenocarcinoma development ', Lung Cancer, vol. 75, no. 2, pp. 156-160 . https://doi.org/10.1016/j.lungcan.2011.07.013
Lung Cancer, 75, 156-60

Item does not contain fulltext BACKGROUND: In a European multicenter prospective study patients with lung cancer were interviewed for smoking history and biological samples centrally collected. The aim of this study was to compare KRAS mutation analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fc5b6f0293afaf2bbb1f081a60c6dd
https://hdl.handle.net/2066/109555

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19th Sir peter freyer memorial lecture and surgical symposium 16th and 17th September 1994

Autor: D. A. McEvoy, B. Connolly, V. Donohue, D. O’Halpin, H. Rowley, T. P. O’Dywer, C. Timon, J. A. McKeever, M. A. Stokes, J. G. Bannigan, M. J. Early, D. M. Baker, Van-Tam Nguyen, D. Bush, J. Jones, J. B. Bourke, K. S. Cross, G. Durkan, M. Stokes, T. Carroll, T. Gorey, K. O’Malley, D. Mulcahy, D. McCormack, J. McElwain, S. C. Natin, T. N. Walsh, T. P. J. Hennessy, K. Carson, R. Page, W. Blunnie, D. C. Moriarty, R. W. G. Watson, D. M. Bouchier-Hayes, H. Abdih, C. J. Kelly, M. Barry, P. Burke, A. Tanner, D. J. Bouchier-Hayes, T. O’Sullivan, A. F. Horgan, D. H. L. Chin, J. A. Mannick, M. L. Rodrick, N. Finnegan, S. T. O’Sullivan, S. F. Wolf, M. C. Barry, C. Condron, R. G. K. Watson, J. D. Evans, C. A. Maxwell-Armstrong, M. K. Barry, K. K. Singh, P. Ralston, C. D. Auld, M. Henderson, J. McCormick, A. D. F. Walls, I. Keogh, M. Kerin, D. O’Hanlon, S. Walsh, P. Kent, J. Callaghan, H. F. Given, P. Madhavan, B. Golden, F. Khan, E. Murphy, N. Couse, G. Burke, P. V. Delaney, R. McLoughlin, P. Kenny, D . O’Hanlon, H. Grimes, S. Reid, P. Neary, M. Nassralla, T. K. Neelamekam, P. Horgan, O. Traynor, P. G. Horgan, J. Hyland, D. M. O’Hanlon, C. O’Boyle, M. J. Duffy, E. W. M. McDermott, D. Reilly, J. J. Fennelly, N. J. O’Higgins, A. McNamara, H. Mullett, D. O’Riordan, E. McDermott, M. Sharp, N. O’Higgins, M. Murphy, M. Little, D. Maher, A. Khalid, P. McCarthy, I. F. Given, C. Bolger, J. P. Phillips, C. Gilligan, S. Zareb, C. Roake, D. S. O’Riordain, D. Farley, C. Grant, J. van Heerden, D. P. O’Brien, M. J. Flynn, F. B. V. Keane, B. Sweeney, D. O’Riordain, A. J. Curran, W. Joyce, D. Smith, H. Gallagher, M. A. Walsh, D. Bouchier-Hayes, J. Phillips, T. O’Brien, S. W. Yusuf, A. C. Perkins, M. Frier, P. W. Wenham, B. R. Hopkinson, G. S. Makin, R. Hind, W. Yusuf, S. C. Whitaker, R. E. Hind, T. A. M. Chuter, G. C. Durkan, M. J. Grenell, M. C. Regan, T. F. Gorey, C. F. Castineira, S. J. Sheehan, M. Wali, M. P. Colgan, D. J. Moore, G. D. Shanik, G. McGreal, J. Kelly, D. Hehir, M. P. Brady, D. M. Sibbering, P. A. M. Holland, A. R. M. Wilson, R. W. Blarney, M. Khurrum Baig, N. Mulligan, B. Farrell, F. O. Cunningham, M. Magd-Eldin, P. Keeling, Y. A. Gul, S. W. Yeo, U. D. Khan, F. Lennon, M. F. Shine, V. Kalidasan, O. Fulena, E. J. Guiney, R. J. Fitzgerald, M. Corbally, A. E. Wood, C. M. Reardon, G. T. McGreal, D. J. Hehir, J. A. O’Donnell, W. O. Kirwan, A. A. Mahomed, A. Keshgar, R. Surna, M. T. Corbally, S. O’Rourke, I. Beckingham, M. C. Bishop, J. Husain, N. Hegarty, J. Calleary, I. Rafi, M. Gilmore, S. M. Saleem, H. P. Singh, T. Aherne, H. P. Redmond, J. McCarthy, D. M. Mulcahy, P. Nicholson, P. Harrington, T. Sharif, H. Smyth, G. Fenelon, J. Pegum, J. Corrigan, A. Jenkinson, A. A. El-Magbri, M. A. Gussail, M. A. Smew, A. Martin, M. Bennett, M. A. Farrell, C. Curran, M. J. Kerin, M. T. P. Caldwell, P. J. Byrne, S. Duggan, A. S. Jones, J. K. Field, D. Monaghan, C. Condren, S. Crerand, M. Kavanagh, P. Dervan, B. Hurson, K. Aiyaswami, D. Evoy, M. Walsh, B. Garrihy, S. Kaf Al-Ghazal, J. O’Donoghue, J. McCann, S. Wagstaff, C. Conroy, M. Dolan, L. Smith, L. Klenerman, J. Noel, V. Waide, D. O’Sullivan, C. Biyani, C. Powell, M. Heal, R. Surana, A. Khan, T. Lynch, T. Sami, W. Baluch, D. Hickey, M. Donovan, P. McLean, D. Murphy, S. Johnston, V. Rastogi, J. Doyle, J. R. Flynn, P. Kelly, M. F. Neligan, S. W. MacGowan, O. Sharkey, A. Bhojwani, C. Barry Walsh, E. Kay, C. Milbum, M. Leader, J. McDermott, D. Moriarty, P. Caushaj, J. M. Fitzpatrick, D. Byrne, W. P. Hederman, N. K. O’Malley, K. H. Chan, P. Fleming, G. C. O’Sullivan, K. Aizaz, A. F. O’Donnell, D. A. Luke, E. M. McGovern, N. Patil, P. Gormley, P. M. McCarthy

Publikováno v: Irish Journal of Medical Science. 163:417-446

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b239240dac64642560bcabf3d83aa7ca
https://doi.org/10.1007/bf02975041

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The Liverpool Statement 2005: priorities for the European Union/United States spiral computed tomography collaborative group

Autor: J K, Field, R A, Smith, S W, Duffy, C D, Berg, R, van Klaveren, C I, Henschke, D, Carbone, P E, Postmus, E, Paci, F R, Hirsch, J L, Mulshine

Publikováno v: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 1(5)

The Liverpool Statement 2005 was developed at the Fourth International Lung Cancer Molecular Biomarkers Workshop in Liverpool (October 27-29, 2005) and focused on the priorities for the European Union/United States (EU-US) Spiral Computed Tomography

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6c82a4ee686c27cf8bad93af69337cae
https://pubmed.ncbi.nlm.nih.gov/17409906

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The Liverpool Lung Project research protocol

Autor: J K, Field, D L, Smith, S, Duffy, A, Cassidy

Publikováno v: International journal of oncology. 27(6)

The Liverpool Lung Project (LLP) is being conducted within a defined geographic area of Merseyside, based on contiguous districts with a high incidence of lung cancer. As well as increasing the scientific understanding of the interactions between the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d2c8bb1a1295db2fa1a077f6a1d0adea
https://pubmed.ncbi.nlm.nih.gov/16273220

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Loss of heterozygosity on chromosomes 3, 9, 13, and 17, including the retinoblastoma locus, in uveal melanoma

Autor: A G, Scholes, T, Liloglou, P, Maloney, S, Hagan, J, Nunn, P, Hiscott, B E, Damato, I, Grierson, J K, Field

Publikováno v: Investigative ophthalmologyvisual science. 42(11)

To identify tumor-suppressor loci that may contribute to the pathogenesis of uveal melanoma.Multiplex fluorescence microsatellite assays were performed on 27 uveal melanomas using markers at 3p25-p26, 3p14.2, 9p21-p23, 13q14, 13q12.3-q13, and 17p13,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bc33379182f7c775dec8aae4105f5925
https://pubmed.ncbi.nlm.nih.gov/11581185

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Additional characterization of a hexanucleotide polymorphic site in the first intron of human H-ras gene: comparative study of its alterations in non-small cell lung carcinomas and sporadic invasive breast carcinomas

Autor: A, Kotsinas, V G, Gorgoulis, P, Zacharatos, G, Mariatos, S, Kokotas, T, Liloglou, J, Ikonomopoulos, V, Zoumpourlis, A, Kyroudi, J K, Field, P J, Asimacopoulos, C, Kittas

Publikováno v: Cancer genetics and cytogenetics. 126(2)

Intron 1 of the human H-ras gene possesses a polymorphism consisting of repetitions of the GGGCCT consensus. Three alleles have been reported at this locus. We confirmed that two, P1 and P2, display four and two repeats, respectively, with their inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::842a515341ce79086b86cc97420a4aee
https://pubmed.ncbi.nlm.nih.gov/11376808

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A new rare allele at the CGG repeat polymorphism in the first intron of human c-H-ras gene

Autor: A, Kotsinas, V G, Gorgoulis, P, Zacharatos, T, Liloglou, P, Leonardou, J, Bramis, T G, Troupis, C, Fotiadis, J K, Field, C, Kittas

Publikováno v: In vivo (Athens, Greece). 15(1)

We have examined a region in the first intron of the human c-H-ras gene containing a CGG repeat. This region was previously shown to be variable in length. The length variation was attributed to the presence of the CGG repeat after estimation of its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::20265b71b2743b6fc66b7dbf061e2c8b
https://pubmed.ncbi.nlm.nih.gov/11286119

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Cancer-specific genomic instability in bronchial lavage: a molecular tool for lung cancer detection

Autor: T, Liloglou, P, Maloney, G, Xinarianos, M, Hulbert, M J, Walshaw, J R, Gosney, L, Turnbull, J K, Field

Publikováno v: Cancer research. 61(4)

We examined genomic instability in DNA from 80 bronchial lavage samples from patients with lung cancer and individuals with no malignant lung disease. We used a multiplex assay of eight fluorescent-tagged microsatellite markers that have a very high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::415f162acc10f29163d0318ee0ff801e
https://pubmed.ncbi.nlm.nih.gov/11245475

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