Zobrazeno 1 - 10
of 339
pro vyhledávání: '"J Javier, Meana"'
Autor:
Elk Kossatz, Rebeca Diez-Alarcia, Supriya A. Gaitonde, Carla Ramon-Duaso, Tomasz Maciej Stepniewski, David Aranda-Garcia, Itziar Muneta-Arrate, Elodie Tepaz, Suwipa Saen-Oon, Robert Soliva, Aida Shahraki, David Moreira, Jose Brea, Maria Isabel Loza, Rafael de la Torre, Peter Kolb, Michel Bouvier, J. Javier Meana, Patricia Robledo, Jana Selent
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract G protein-coupled receptors (GPCRs) are sophisticated signaling machines able to simultaneously elicit multiple intracellular signaling pathways upon activation. Complete (in)activation of all pathways can be counterproductive for specific t
Externí odkaz:
https://doaj.org/article/455c7d7ebe814812996e6683dd1c4a42
Autor:
Bohan Zhu, Richard I Ainsworth, Zengmiao Wang, Zhengzhi Liu, Salvador Sierra, Chengyu Deng, Luis F Callado, J Javier Meana, Wei Wang, Chang Lu, Javier González-Maeso
Publikováno v:
eLife, Vol 12 (2024)
Genome-wide association studies have revealed >270 loci associated with schizophrenia risk, yet these genetic factors do not seem to be sufficient to fully explain the molecular determinants behind this psychiatric condition. Epigenetic marks such as
Externí odkaz:
https://doaj.org/article/3d93059727454ba289151c44ddd8e836
Autor:
Qiang Zhang, Sai Ma, Zhengzhi Liu, Bohan Zhu, Zirui Zhou, Gaoshan Li, J. Javier Meana, Javier González-Maeso, Chang Lu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract The genome-wide DNA methylation profile, or DNA methylome, is a critical component of the overall epigenomic landscape that modulates gene activities and cell fate. Single-cell DNA methylomic studies offer unprecedented resolution for detect
Externí odkaz:
https://doaj.org/article/996b421228474e3b866bd4eb054878ca
Autor:
Unai Sarriés-Serrano, Lluis Miquel-Rio, Amat Amat-Lopez, Veronica Paz, J. Javier Meana, Analia Bortolozzi
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S494- (2023)
Externí odkaz:
https://doaj.org/article/acf3e599c6d341338108e9eb9a46b450
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S555- (2023)
Externí odkaz:
https://doaj.org/article/2a83885fe0434d6e9f0e388de9376ede
Autor:
Oihane Martinez-Peula, Guadalupe Rivero, Eva Munarriz-Cuezva, Jon Delacuesta-Barrutia, Javier Gonzalez-Maeso, Amaia-Maite Erdozain, J. Javier Meana, Alfredo Ramos-Miguel
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S607- (2023)
Externí odkaz:
https://doaj.org/article/aa24c9cc205c4c9683f7a9cc5d5397b9
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S609- (2023)
Externí odkaz:
https://doaj.org/article/af5023147fcc495abc9eac7a524ac417
Autor:
Cristina Lorca, María Fernández-Rhodes, Jose Antonio Sánchez Milán, María Mulet, Félix Elortza, Alfredo Ramos-Miguel, Luis F. Callado, J. Javier Meana, Maria Mur, Iolanda Batalla, Elisabet Vilella, Aida Serra, Xavier Gallart-Palau
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 129 (2024)
Extracellular vesicles (EVs) are tiny membranous structures that mediate intercellular communication. The role(s) of these vesicles have been widely investigated in the context of neurological diseases; however, their potential implications in the ne
Externí odkaz:
https://doaj.org/article/bd4c98dd63eb4a2f91b36ed60762a094
Autor:
Iria Brocos-Mosquera, Patricia Miranda-Azpiazu, Carolina Muguruza, Virginia Corzo-Monje, Benito Morentin, J. Javier Meana, Luis F. Callado, Guadalupe Rivero
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Postsynaptic α2A-adrenoceptor density is enhanced in the dorsolateral prefrontal cortex (DLPFC) of antipsychotic-treated schizophrenia subjects. This alteration might be due to transcriptional activation, and could be regulated by epigeneti
Externí odkaz:
https://doaj.org/article/b8db53681558470383aa2e9e41a42f88
Autor:
Rebeca Diez-Alarcia, Carolina Muguruza, Guadalupe Rivero, Aintzane García-Bea, Vanessa Gómez-Vallejo, Luis F. Callado, Jordi Llop, Abraham Martín, J. Javier Meana
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The status of serotonin 5HT2A receptors (5HT2ARs) in schizophrenia has been controversial. In vivo positron emission tomography neuroimaging and in vitro post-mortem binding studies have reported conflicting results about 5HT2AR densit
Externí odkaz:
https://doaj.org/article/ab7a5744879b4c13a57c83edf01eeb7b