Zobrazeno 1 - 10 of 500 pro vyhledávání: '"J J Windle"'
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Akademický článek
A Multifunctional Therapeutic Strategy Using P7C3 as A Countermeasure Against Bone Loss and Fragility in An Ovariectomized Rat Model of Postmenopausal Osteoporosis.
Autor: Wei, Fei1 (AUTHOR), Hughes, Megan2 (AUTHOR), Omer, Mahmoud1 (AUTHOR), Ngo, Christopher1,3 (AUTHOR), Pugazhendhi, Abinaya Sindu1 (AUTHOR), Kolanthai, Elayaraja4 (AUTHOR), Aceto, Matthew3 (AUTHOR), Ghattas, Yasmine3 (AUTHOR), Razavi, Mehdi1,3 (AUTHOR), Kean, Thomas J1,3 (AUTHOR), Seal, Sudipta1,3,4 (AUTHOR), Coathup, Melanie1,3 (AUTHOR) melanie.coathup@ucf.edu
Publikováno v: Advanced Science. 6/5/2024, Vol. 11 Issue 21, p1-27. 27p.
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2
Autophagy promotes T-cell survival through degradation of proteins of the cell death machinery
Autor: I G Garcia, Songguang Ju, D G Roodman, Binfeng Lu, J J Windle, Gang Li, J R Kovacs, Q Yang, X Zhang, C Li
Autophagy is implicated in regulating cell death in activated T cells, but the underlying mechanism is unclear. Here, we show that inhibition of autophagy via Beclin 1 gene deletion in T cells leads to rampant apoptosis in these cells upon TCR stimul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362653fcb8d1bf8ecbe3ed883b7f4ab5
https://europepmc.org/articles/PMC3252822/
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3
Tissue-Specific Gene Expression in the Pituitary: The Glycoprotein Hormone α-Subunit Gene Is Regulated by a Gonadotrope-Specific Protein
Autor: F, Horn, J J, Windle, K M, Barnhart, P L, Mellon
Publikováno v: Molecular and Cellular Biology. 12:2143-2153
The molecular mechanisms for the development of multiple distinct endocrine cell types in the anterior pituitary have been an area of intensive investigation. Though the homeodomain protein Pit-1/GHF-1 is known to be involved in differentiation of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5c8d5eff440a03bd0dbbf0634637c3
https://doi.org/10.1128/mcb.12.5.2143-2153.1992
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4
Retinoblastoma in transgenic mice: models of hereditary retinoblastoma
Autor: M D, Mills, J J, Windle, D M, Albert
Publikováno v: Survey of ophthalmology. 43(6)
Retinoblastoma, the most common intraocular malignancy ill childhood, has served as a paradigm for the study of genetic mechanisms of oncogenesis. The retinoblastoma susceptibility gene RB1 was the first tumor suppressor gene to be cloned, and geneti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::917edeae0fcb17c71d6446926bc0621b
https://pubmed.ncbi.nlm.nih.gov/10416793
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5
Transgenic mice with pigmented intraocular tumors: tissue of origin and treatment
Autor: N A, Syed, J J, Windle, S R, Darjatmoko, J M, Lokken, R A, Steeves, R, Chappell, I H, Wallow, B A, Koop, G, Mangold, K A, Howes, D M, Albert
Publikováno v: Investigative ophthalmologyvisual science. 39(13)
To describe the cell of origin, tumor progression, light and electron microscopic appearance, immunohistochemical properties, and response to frequently used anticancer therapies in two transgenic models of intraocular melanoma.Two lines of transgeni
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::608f0eb3395b96a5d5320e317dc0f144
https://pubmed.ncbi.nlm.nih.gov/9856795
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6
Apoptosis in the murine rd1 retinal degeneration is predominantly p53-independent
Autor: R M, Hopp, N, Ransom, S G, Hilsenbeck, D S, Papermaster, J J, Windle
Publikováno v: Molecular vision. 4
To determine if p53 mediates apoptosis in photoreceptors of retinal degeneration, rd1, mice.The rd1/rd1 mice were interbred with p53 null mice to generate p53-/- rd1/rd1 and p53+/+ rd1/rd1 mice. Rates of loss and incidence of apoptosis in rod photore
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7e8df82f1daa3f032457a298725be0e0
https://pubmed.ncbi.nlm.nih.gov/9485488
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7
Photoreceptor cell tumors in transgenic mice
Autor: K A, Howes, J G, Lasudry, D M, Albert, J J, Windle
Publikováno v: Investigative ophthalmologyvisual science. 35(2)
To produce transgenic mice that express the SV40 T-antigen oncogene specifically in photoreceptor cells, giving rise to retinoblastoma tumors of photoreceptor cell origin; to characterize the mice with regard to transgene expression and pathology and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::06744f7561e4af1fd0c9204c8c4ef725
https://pubmed.ncbi.nlm.nih.gov/8112979
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9
Immortalized hypothalamic gonadotropin-releasing hormone neurons
Autor: P L, Mellon, W C, Wetsel, J J, Windle, M M, Valença, P C, Goldsmith, D B, Whyte, S A, Eraly, A, Negro-Vilar, R I, Weiner
Publikováno v: Ciba Foundation symposium. 168
The neuroendocrine hypothalamus has been intensively studied using whole animals and tissue slices. However, it has been difficult to approach questions at the molecular and cellular level. By targeting expression of the oncogene product, simian viru
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::076f19e0509a2ea44e7ae7e5906b73cf
https://pubmed.ncbi.nlm.nih.gov/1330456
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