Zobrazeno 1 - 10
of 37
pro vyhledávání: '"J J Sninsky"'
Publikováno v:
Genome Research. 3:S39-S47
Roche Molecular Systems, Inc., Alameda, California 94501 Although simple in concept, PCR requires a myriad of complex interactions between template, primers, deoxynucleoside triphosphates, and DNA polymerase to successfully accomplish targeted amplif
Autor:
Margaret Simpson, Frank S. Rhame, Keith Henry, J. B. Jackson, Kim J. Sannerud, S. Y. Kwok, J. J. Sninsky, Henry H. Balfour, J. S. Hopsicker
Publikováno v:
Journal of Clinical Microbiology. 28:16-19
Between February 1987 and October 1988, peripheral mononuclear blood cells (PBMC) from 409 adult individuals antibody positive by Western (immuno-)blot for human immunodeficiency virus type 1 (HIV-1) (56 acquired immunodeficiency syndrome [AIDS] pati
Publikováno v:
Cancer research. 53(11)
Pancreatic adenocarcinomas are known to have a high incidence of K-ras gene mutations. Differential diagnosis of pancreatic cancer and chronic pancreatitis sometimes presents a clinical dilemma. We recently developed a highly sensitive and specific p
Autor:
J J, Sninsky
Publikováno v:
Lymphology. 23(2)
Although the detection of antibodies to a specific pathogen is used initially as the assay of choice, direct detection of human retroviruses is difficult. First, only a small fraction of cells are infected in the peripheral blood and lymphatic tissue
Publikováno v:
Journal of acquired immune deficiency syndromes. 3(5)
Recently a new technique, the polymerase chain reaction (PCR), has been used for the detection and characterization of HIV-1 proviral DNA and viral RNA. These reports support the notion that the PCR is more sensitive and specific than other establish
Publikováno v:
Molecular Diagnosis. 5:1-1
Publikováno v:
Journal of Virology. 57:173-182
A segment from the pre-s region of the woodchuck hepatitis virus (WHV) was inserted into an open reading frame vector allowing for the expression in Escherichia coli of viral determinants as part of a fusion protein. The bacterially synthesized fusio
Publikováno v:
Journal of Virology. 62:4786-4790
A segment of the largest open reading frame of hepatitis B virus (HBV) was inserted into an open reading frame vector directing the expression in Escherichia coli of a fusion molecule containing 143 HBV-encoded amino acids. The fusion protein was use
Publikováno v:
Journal of Virology. 57:101-109
Sequence analysis of the hepatitis B virus (HBV) genome revealed the presence of an open reading frame (ORF X) which has the potential to encode a 154-amino acid polypeptide. A fusion protein containing 145 of the amino acids encoded by ORF X and 8 a
Autor:
J. J. Sninsky, J. B. Jackson, J. R. Edson, Kim J. Sannerud, S. Y. Kwok, Henry H. Balfour, J. S. Hopsicker
Publikováno v:
Transfusion. 29(3)
In order to confirm the presence and determine the frequency of human immunodeficiency virus, type 1 (HIV-1) infection prior to antibody production, 23 healthy women with histories of repeated unprotected sexual exposure to HIV-1 infected hemophiliac