Výsledky vyhledávání

Immune modulation after measles vaccination of 6–9 months old Bangladeshi infants

Autor: Sibylle Schneider-Schaulies, J J Schnorr, Tasnim Azim, Felicity T. Cutts, S M Akramuzzaman, Volker ter-Meulen, J. G. Wheeler, M.Samiul Alam

Publikováno v: Vaccine. 19:1503-1510

Measles still causes high mortality in children younger than 1 year of age. Administration of high titre measles vaccines before 7 months of age led to increased overall mortality, raising questions as to the immunological effects of measles vaccine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c99c51bc8158158a1d133fa0c073b2c
https://doi.org/10.1016/s0264-410x(00)00349-2

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Measles virus-induced immunosuppression in cotton rats is associated with cell cycle retardation in uninfected lymphocytes

Autor: J J Schnorr, Stefan Niewiesk, H Ohnimus, Christian Jassoy, Michaela Götzelmann, Sibylle Schneider-Schaulies, Volker ter Meulen

Publikováno v: Journal of General Virology. 80:2023-2029

Measles virus (MV)-induced immune suppression during acute measles often leads to secondary viral, bacterial and parasitic infections which severely complicate the course of disease. Previously, we have shown that cotton rats are a good animal model

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f304be874d1d7803898c2a5082f888
https://doi.org/10.1099/0022-1317-80-8-2023

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Human MxA Protein Confers Resistance to Semliki Forest Virus and Inhibits the Amplification of a Semliki Forest Virus-Based Replicon in the Absence of Viral Structural Proteins

Autor: J J Schnorr, Hans Peter Hefti, Heinrich Landis, Sibylle Schneider-Schaulies, Angela Simon-Jodicke, Jovan Pavlovic, Andreas Klöti, Claudio Di Paolo

Publikováno v: Journal of Virology. 72:1516-1522

Mx proteins form a small family of interferon (IFN)-induced GTPases with potent antiviral activity against various negative-strand RNA viruses. To examine the antiviral spectrum of human MxA in homologous cells, we stably transfected HEp-2 cells with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a97a9e8f57b4d64ba80aafe4a7de78
https://doi.org/10.1128/jvi.72.2.1516-1522.1998

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Cell cycle arrest rather than apoptosis is associated with measles virus contact-mediated immunosuppression in vitro

Autor: J Schlender, M Seufert, V ter Meulen, Ian C. D. Johnston, Sibylle Schneider-Schaulies, Jannie Borst, J J Schnorr

Publikováno v: Journal of General Virology. 78:3217-3226

Acute measles is associated with pronounced immunosuppression characterized both by leukopenia and impaired lymphocyte functions. In an earlier study, we found that mitogen-dependent proliferation of uninfected human peripheral blood lymphocytes (PBL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe733add87eec9ec6124b8eb3ada2b2b
https://doi.org/10.1099/0022-1317-78-12-3217

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Receptor (CD46) modulation and complement-mediated lysis of uninfected cells after contact with measles virus-infected cells

Autor: J J Schnorr, J Schlender, Jürgen Schneider-Schaulies, L M Dunster, Sibylle Schneider-Schaulies, V ter Meulen

Publikováno v: Journal of Virology. 70:255-263

Recently, it has been observed that the infection of human target cells with certain measles virus (MV) strains leads to the downregulation of the major MV receptor CD46. Here we report that CD46 downregulation can be rapidly induced in uninfected ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a24deaa753999f1d848cfe199fc5ab
https://doi.org/10.1128/jvi.70.1.255-263.1996

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Comparative analysis of two coxsackievirus B3 strains: putative influence of virus-receptor interactions on pathogenesis

Autor: H-C, Selinka, A, Wolde, A, Pasch, K, Klingel, J-J, Schnorr, J-H, Küpper, A M, Lindberg, R, Kandolf

Publikováno v: Journal of medical virology. 67(2)

Strain-specific differences in the interaction of coxsackievirus B3 (CVB3) with the coxsackievirus-adenovirus receptor (CAR) and the decay-accelerating factor (DAF) co-receptor proteins were investigated using a non-haemagglutinating (CVB3) and a hae

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::80389173f4c51de9af08700675a2e54e
https://pubmed.ncbi.nlm.nih.gov/11992583

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Measles virus-induced immune suppression in the cotton rat (Sigmodon hispidus) model depends on viral glycoproteins

Autor: V ter Meulen, J. C. S. Clegg, I. Eisenhuth, Stefan Niewiesk, J J Schnorr, A. Fooks, Sibylle Schneider-Schaulies

Publikováno v: Journal of virology. 71(10)

Immune suppression during measles accounts for most of the morbidity and mortality associated with the virus infection. Experimental study of this phenomenon has been hampered by the lack of a suitable animal model. We have used the cotton rat to dem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b8307eed3dd441adeb387b1ec3c1f0
https://pubmed.ncbi.nlm.nih.gov/9311794

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Induction of maturation of human blood dendritic cell precursors by measles virus is associated with immunosuppression

Autor: J J Schnorr, E. Kampgen, S. Xanthakos, P. Keikavoussi, Sibylle Schneider-Schaulies, V ter Meulen

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 94(10)

As well as inducing a protective immune response against reinfection, acute measles is associated with a marked suppression of immune functions against superinfecting agents and recall antigens, and this association is the major cause of the current

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a149bfb7ddbbcd5e313e7a41742e18
https://pubmed.ncbi.nlm.nih.gov/9144236

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Receptor usage and differential downregulation of CD46 by measles virus wild-type and vaccine strains

Autor: V ter Meulen, J J Schnorr, U. Brinckmann, Jürgen Schneider-Schaulies, L M Dunster, Sibylle Schneider-Schaulies, K. Baczko, Uwe G. Liebert

Recently, two cell surface molecules, CD46 and moesin, have been found to be functionally associated with measles virus (MV) infectivity of cells. We investigated the receptor usage of MV wild-type, subacute sclerosing panencephalitis, and vaccine st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa858739f0e2091c4896f2821929a599
https://europepmc.org/articles/PMC42078/

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The role of host factors in measles virus persistence

Autor: J J Schnorr, L M Dunster, Volker ter Meulen, Sibylle Schneider-Schaulies, Jürgen Schneider-Schaulies

As critical steps in the life cycle of measles virus (MV), the efficiency of uptake into and replication in susceptible host cells are governed by cellular determinants. Measles virus infections of cells of the human CNS are characterized by particul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a3f846511f4c29540c2f6d016f0fd7
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-54944

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