Výsledky vyhledávání - "J J Schlesinger"

New Approaches to Flavivirus Vaccine Development

Autor: K H Eckels, J R Putnak, J J Schlesinger

Publisher Summary This chapter discusses new approaches to flavivirus vaccine development. Flaviviruses are small, enveloped single-positive strand RNA viruses of the newly established family, Flaviviridae. Genetically and serologically related to ea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ffa18f1197ab112549c6e750a184fd83
https://doi.org/10.1016/b978-0-7506-9265-6.50018-x

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Immunogenicity of a purified fragment of 17D yellow fever envelope protein

Autor: M W, Brandriss, J J, Schlesinger, E E, Walsh

Publikováno v: The Journal of infectious diseases. 161(6)

Information on the immunogenic properties of purified flavivirus proteins may be useful in the development of recombinant or synthetic peptide vaccines. Using a monoclonal antibody, an attempt was made to purify the envelope (E) protein of 17D yellow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::45980082544dccb06d568d4d3c17743f
https://pubmed.ncbi.nlm.nih.gov/1693159

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Infection of a macrophage-like cell line, P388D1 with reovirus; effects of immune ascitic fluids and monoclonal antibodies on neutralization and on enhancement of viral growth

Autor: S J Burstin, M W Brandriss, J J Schlesinger

Publikováno v: The Journal of Immunology. 130:2915-2919

We studied the effect of antibody on the growth of reovirus, serotypes 1 and 3, in P388D1, a continuous mouse macrophage-like cell line. Enhanced growth of virus was observed when cells were infected in the presence of nonneutralizing monoclonal anti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1830ea3bf8630f502b56eafd0aff553b
https://doi.org/10.4049/jimmunol.130.6.2915

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Protection against 17D yellow fever encephalitis in mice by passive transfer of monoclonal antibodies to the nonstructural glycoprotein gp48 and by active immunization with gp48

Autor: J J Schlesinger, M W Brandriss, E E Walsh

Publikováno v: The Journal of Immunology. 135:2805-2809

The protective capacity of antiviral antibodies has generally been considered to depend on their interactions with structural components of the virion. Here we report protection against lethal 17D yellow fever virus (YF) encephalitis of mice by passi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc1464ce78e2eb7242c74134a4b05d78
https://doi.org/10.4049/jimmunol.135.4.2805

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Growth of 17D yellow fever virus in a macrophage-like cell line, U937: role of Fc and viral receptors in antibody-mediated infection

Autor: J J Schlesinger, M W Brandriss

Publikováno v: The Journal of Immunology. 127:659-665

Growth characteristics of 17D yellow fever virus (17D-YF) and conditions for infection were studied in U937, a macrophage-like, Fc receptor-bearing continuous human cell line. Antibody to 17D-YF was obtained by immunization of normal subjects with 17

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::583ef82a293b768716ad92e42f8c3e64
https://doi.org/10.4049/jimmunol.127.2.659

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