The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane

Autor: Suzanne Heemskerk, Rachel Sayer, Colin D.A. Brown, Miriam Huls, Amy S. Windass, Rosalinde Masereeuw, Frans G. M. Russel, J. J. M. W. van den Heuvel

Publikováno v: Kidney International. Supplement, 73, 220-5
Kidney International. Supplement, 73, 2, pp. 220-5

Contains fulltext : 70782.pdf (Publisher’s version ) (Closed access) The Breast Cancer Resistance Protein (BCRP/ABCG2) is a transporter restricting absorption and enhancing excretion of many compounds including anticancer drugs. This transporter is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3502e75842d74db523629ba4efb5b4e

Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4

Autor: A A K, El-Sheikh, J J M W, van den Heuvel, J B, Koenderink, F G M, Russel

Publikováno v: British journal of pharmacology. 155(7)

The xanthine oxidase inhibitors allopurinol and oxypurinol are used to treat hyperuricaemia, whereas loop and thiazide diuretics can cause iatrogenic hyperuricaemia. Some uricosuric drugs and salicylate have a bimodal action on urate renal excretion.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4e126ebac40f030797ff21243f21a90c
https://pubmed.ncbi.nlm.nih.gov/18724382

Systematic analysis of three FHM genes in 39 sporadic patients with hemiplegic migraine

Autor: B. B. A. de Vries, Rune R. Frants, Jan B. Koenderink, G.M. Terwindt, Michael Pusch, Martin Dichgans, J. J. M. W. van den Heuvel, A.M.J.M. van den Maagdenberg, M. D. Ferrari, K R J Vanmolkot, Joost Haan, E. H. van den Boogerd, AH Stam, T. Freilinger, Elena Babini

Publikováno v: Neurology, 69, 2170-6
Neurology, 69, 23, pp. 2170-6
Neurology 69 (2007): 2170–2176. doi:10.1212/01.wnl.0000295670.01629.5a
info:cnr-pdr/source/autori:Boukje de Vries; Tobias Freilinger; Kaate R.J. Vanmolkot; Jan B. Koenderink; Anine H. Stam; Gisela M. Terwindt; Elena Babini; Eelke H. van den Boogerd; Jeroen J.M.W. van den Heuvel; Rune R. Frants; Joost Haan; Michael Pusch; Arn M.J.M. van den Maagdenberg; Michel D. Ferrari; Martin Dichgans/titolo:Systematic analysis of three FHM genes in 39 sporadic patients with hemiplegic migraine/doi:10.1212%2F01.wnl.0000295670.01629.5a/rivista:Neurology/anno:2007/pagina_da:2170/pagina_a:2176/intervallo_pagine:2170–2176/volume:69

Background: Familial (FHM) and sporadic (SHM) hemiplegic migraine are severe subtypes of migraine associated with transient hemiparesis. For FHM, three genes have been identified encoding subunits of a calcium channel (CACNA1A), a sodium–potassium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bbac51a840baea029eceae2fbf1775
http://hdl.handle.net/2066/52271

Severe episodic neurological deficits and permanent mental retardation in a child with a novel FHM2 ATP1A2 mutation

Autor: Rune R. Frants, E. H. van den Boogerd, J. J. M. W. van den Heuvel, Jan B. Koenderink, A.M.J.M. van den Maagdenberg, Anine H. Stam, B. B. A. De Vries, H Stroink, E. E. Kors, Michel D. Ferrari, Joost Haan, K R J Vanmolkot, Gisela M. Terwindt

Publikováno v: Annals of Neurology, 59, 310-4
Annals of Neurology, 59, 2, pp. 310-4

Objective Attacks of familial hemiplegic migraine (FHM) are usually associated with transient, completely reversible symptoms. Here, we studied the ATP1A2 FHM2 gene in a young girl with episodes of both very severe and transient neurological symptoms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f770173220c6727847d556570df4bcf
http://hdl.handle.net/2066/49308