Zobrazeno 1 - 10
of 30
pro vyhledávání: '"J J Keirns"'
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(12)
The study objectives were to characterize the metabolism of nevirapine (NVP) in mouse, rat, rabbit, dog, monkey, and chimpanzee after oral administration of carbon-14-labeled or -unlabeled NVP. Liquid scintillation counting quantitated radioactivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::732051f2557adf01a8a54f7d079a4f37
https://pubmed.ncbi.nlm.nih.gov/10570025
https://pubmed.ncbi.nlm.nih.gov/10570025
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(12)
Nevirapine (NVP), a non-nucleoside inhibitor of HIV-1 reverse transcriptase, is concomitantly administered to patients with a variety of medications. To assess the potential for its involvement in drug interactions, cytochrome P-450 (CYP) reaction ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6629b920a0f8f1d2fca047eb271e1341
https://pubmed.ncbi.nlm.nih.gov/10570031
https://pubmed.ncbi.nlm.nih.gov/10570031
Autor:
J J Keirns, J H Wall, John A. D. Cooper, J Oliver, E N Schachter, R B Fick, W W Merrill, M G Buck
Publikováno v:
Environmental Health Perspectives
Purified aqueous extracts of cotton bract induce acute airway constriction in healthy volunteers never before exposed to cotton bract. The response is similar to that of textile workers who inhale cotton dust. Approximately 60% of volunteers respond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345defb9e2dca2cdcbeeacfd2a1e7316
http://europepmc.org/articles/PMC1474373
http://europepmc.org/articles/PMC1474373
Autor:
Robert F. Curl, J. J. Keirns
Publikováno v:
The Journal of Chemical Physics. 48:3773-3778
The microwave spectrum of HF||H2C=C–C=O has been studied in the region 8–26 GHz. Two planar rotational isomers have been assigned. Only a‐type transitions have been assigned for ground‐state and first and second torsional excited states of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::503c5ecf556e23cffe8010c79d230898
https://doi.org/10.1063/1.1669684
https://doi.org/10.1063/1.1669684
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 11(6)
Metaproterenol (1-(3,5-dihydroxyphenyl)-2-isopropylaminoethanol) is primarily converted in humans to metaproterenol-3-O-sulfate following oral administration. Ion exchange column chromatography with a gradient of ammonium acetate buffer permitted the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c91a439aa8dfda59d665932fd999bb0a
https://pubmed.ncbi.nlm.nih.gov/6140141
https://pubmed.ncbi.nlm.nih.gov/6140141
Publikováno v:
The American journal of the medical sciences. 268(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41ca1d4f119f5f3d74bbfd9a19190166
https://pubmed.ncbi.nlm.nih.gov/4153310
https://pubmed.ncbi.nlm.nih.gov/4153310
Publikováno v:
Methods in enzymology. 38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2a56ee25c5157f8cfd5e4e40bfe4362
https://pubmed.ncbi.nlm.nih.gov/4156068
https://pubmed.ncbi.nlm.nih.gov/4156068
Autor:
M W, Bitensky, N, Miki, J J, Keirns, M, Keirns, J M, Baraban, J, Freeman, M A, Wheeler, J, Lacy, F R, Marcus
Publikováno v:
Advances in cyclic nucleotide research. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7c9ed4f9960f24b4faa573473e8d6fc
https://pubmed.ncbi.nlm.nih.gov/165667
https://pubmed.ncbi.nlm.nih.gov/165667
Publikováno v:
Experimental eye research. 18(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18863986aacf96a94717db289ecab111
https://pubmed.ncbi.nlm.nih.gov/4366186
https://pubmed.ncbi.nlm.nih.gov/4366186
Publikováno v:
Arzneimittel-Forschung. 35(1A)
Tablet cores of clonidine (Catapres) showing varying rates of in vitro dissolution were administered in a crossover study with intravenous clonidine to determine the rate of absorption into the systemic circulation in humans. Excellent bioavailabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db064a90dcdf15c5489c000b9aad0705
https://pubmed.ncbi.nlm.nih.gov/4039184
https://pubmed.ncbi.nlm.nih.gov/4039184