Zobrazeno 1 - 10
of 53
pro vyhledávání: '"J J Hooks"'
Publikováno v:
The Journal of Immunology. 151:3381-3389
The murine coronavirus, mouse hepatitis virus (MHV), JHM strain, induces a biphasic retinal disease in adult BALB/c mice. In the early phase of the disease, day 1 to 7, a retinal vasculitis is noted and is associated with the presence of virus partic
Publikováno v:
Investigative ophthalmologyvisual science. 42(10)
Cyclooxygenases (COX) orchestrate a variety of homeostatic processes and participate in various pathophysiological conditions. The retinal pigment epithelium (RPE) cell performs a variety of regulatory functions within the retina. The conditions unde
Publikováno v:
Investigative ophthalmologyvisual science. 42(1)
The antiviral activity of first and second generation antisense oligonucleotides on human cytomegalovirus (CMV) replication was evaluated in two cell systems, the traditional system on human fibroblasts and on human retinal pigment epithelial (HRPE)
Publikováno v:
Investigative ophthalmologyvisual science. 41(10)
To evaluate the possible roles of apoptosis in the murine retinopathy induced by coronavirus.Mice were inoculated with virus intravitreally. Mouse eyes harvested at varying times after inoculation were evaluated for apoptotic and immunologic events b
Publikováno v:
Investigative ophthalmologyvisual science. 40(5)
Studies have shown that interferon (IFN)-gamma stimulates expression of intercellular adhesion molecule-1 (ICAM-1), major histocompatibility complex (MHC) class II, interleukin (IL)-6, and inducible nitric oxide synthase and inhibits replication of T
Publikováno v:
Investigative ophthalmologyvisual science. 37(5)
Cytomegalovirus (CMV) infections are frequent complications in patients who have undergone kidney and bone marrow transplant and in patients with acquired immune deficiency syndrome. The mechanism by which CMV is activated and replicated within the r
Publikováno v:
Investigative ophthalmologyvisual science. 37(1)
Retinal inflammatory and degenerative processes in humans and animals frequently are associated with genetic factors. The murine coronavirus, mouse hepatitis virus (MHV), JHM strain, induces a biphasic retinal disease in adult BALB/c mice. The geneti
Publikováno v:
Investigative ophthalmologyvisual science. 36(12)
To characterize glutathione (GSH) transport by cultured human retinal pigment epithelial (HRPE) cells.Cultured HRPE cells were pretreated with acivicin for GSH efflux and with buthionine sulfoximine for GSH uptake to prevent the breakdown and resynth
Publikováno v:
Investigative ophthalmologyvisual science. 34(9)
To examine the mechanism(s) of interferon (IFN) induced expression of major histocompatibility complex (MHC) class 1 molecules on the human retinoblastoma cell line, Y-79.Y-79 cells were incubated in the presence of IFN-alpha, -beta, and -gamma. Y-79
Publikováno v:
The Journal of biological chemistry. 268(21)
Studies reported previously from this laboratory have shown that microsomal membranes of the vertebrate retinal pigment epithelium (RPE) contain an RPE-specific 65-kDa protein, RPE65, which bears the determinant recognized by the strictly tissue-spec