A point-prevalence study of body mass indices in HIV-positive and HIV-negative patients admitted to hospital with COVID-19 in South Africa

Autor: A Parker, A G B Broadhurst, M S Moolla, L Amien, R Ahmed, J J Taljaard, G Meintjes, P Nyasulu, C F N Koegelenberg

Publikováno v: African Journal of Thoracic and Critical Care Medicine, Pp 127-130 (2023)

Background. Obesity is now well recognised as a risk factor for severe COVID‐19, but the true prevalence of obesity in hospitalised adults with COVID‐19 remains unclear because formal body mass indices (BMIs) are not routinely measured on admissi

Externí odkaz: https://doaj.org/article/c975693c6ee345669c7cbc2c7181855d

Bacterial infection, antibiotic use and COVID-19: Lessons from the intensive care unit

Autor: M S, Moolla, K, Reddy, I, Fwemba, P S, Nyasulu, J J, Taljaard, A, Parker, E H, Louw, A, Nortje, M A, Parker, U, Lalla, C F N, Koegelenberg, B W, Allwood

Publikováno v: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 111(6)

Empirical broad-spectrum antibiotics are frequently prescribed to patients with severe COVID-19, motivated by concern about bacterial coinfection. There is no evidence of benefit from such a strategy, while the dangers of inappropriate antibiotics ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f2fa4cf542996e4b950ca5ffa621c838
https://pubmed.ncbi.nlm.nih.gov/34382570

Leadership and early strategic response to the SARS-CoV-2 pandemic at a COVID-19 designated hospital in South Africa

Autor: Mark F. Cotton, Rakesh D. Mistry, Helena Rabie, Rory Leisegang, Sa'ad Lahri, A. Aucamp, U Lalla, D. S. Erasmus, Wayne P. Smith, J J Taljaard, A. Mowlana, Arifa Parker, Coenraad F.N. Koegelenberg, S. Karamchand, J. Meintjes, P. Ciapparelli, R. Abrahams, Mohammed Rafique Moosa, M. Van Schalkwyk, Hans Prozesky, Neshaad Schrueder

Publikováno v: SAMJ: South African Medical Journal, Volume: 110, Issue: 6, Pages: 1-3, Published: JUN 2020

While many countries are preparing to face the COVID-19 pandemic, the reported cases in Africa remain low. With a high burden of both communicable and non-communicable disease and a resource-constrained public healthcare system, sub-Saharan Africa is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88be79970a0ace3844209204bd6a806
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742020000600007&lng=en&tlng=en

A severity-of-illness score in patients with tuberculosis requiring intensive care

Autor: E M Irusen, Coenraad F.N. Koegelenberg, Brian W. Allwood, U Lalla, J J Taljaard

Publikováno v: South African Medical Journal; Vol. 111 No. 3 (2021); 245-249
SAMJ: South African Medical Journal, Volume: 111, Issue: 3, Pages: 245-249, Published: MAR 2021

Background. We previously retrospectively validated a 6-point severity-of-illness score aimed at identifying patients at risk of dying of tuberculosis (TB) in the intensive care unit (ICU). Parameters included septic shock, HIV infection with a CD4 c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0909f5c07b4a896e3bea3f74dba7b2c
https://doi.org/10.7196/samj.2021.v111i3.14609

Evidence of tenofovir resistance in chronic hepatitis B virus (HBV) infection: An observational case series of South African adults

Autor: J J Taljaard, Mariateresa de Cesare, Monique Andersson, Susan Hugo, Joshua B Singer, Wolfgang Preiser, Jolynne Mokaya, Tongai Maponga, Philippa C Matthews, David Bonsall, Anna L McNaughton, Christo van Rensburg, Vattipally B. Sreenu, Shiraaz Gabriel, Marije van Schalkwyk, Eleanor Barnes

Publikováno v: Journal of Clinical Virology
Mokaya, J, Maponga, T G, McNaughton, A L, Van Schalkwyk, M, Hugo, S, Singer, J B, Sreenu, V B, Bonsall, D, de Cesare, M, Andersson, M, Gabriel, S, Taljaard, J, Barnes, E, Preiser, W, Van Rensburg, C & Matthews, P C 2020, ' Evidence of tenofovir resistance in chronic hepatitis B virus (HBV) infection : An observational case series of South African adults ', Journal of Clinical Virology, vol. 129, pp. 104548 . https://doi.org/10.1016/j.jcv.2020.104548

IntroductionTenofovir disoproxil fumarate (TDF) is widely recommended for treatment of chronic hepatitis B virus (HBV) infection because it is safe, affordable and has a high genetic barrier to resistance. TDF resistance associated mutations (RAMs) h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8df7bbaab9e9293b5a21d4cd7945ff
https://doi.org/10.1016/j.jcv.2020.104548