Výsledky vyhledávání - "J J, Sevigny"

Growth hormone secretagogue MK-677: No clinical effect on AD progression in a randomized trial

Autor: J J, Sevigny, J M, Ryan, C H, van Dyck, Y, Peng, C R, Lines, M L, Nessly, M L, Stedman

Publikováno v: Neurology. 71:1702-1708

Background: In animals, insulin-like growth factor-1 (IGF-1) increases clearance of β-amyloid, a pathologic hallmark of Alzheimer disease (AD), from the CNS. Serum IGF-1 level decreases with age, and shows a further decrease in AD. We examined wheth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9244bf817ca87d6bf500efc9f53fa06c
https://doi.org/10.1212/01.wnl.0000335163.88054.e7

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Akademický článek

Nasal Administration of Cationic Nanoemulsions as CD73-siRNA Delivery System for Glioblastoma Treatment: a New Therapeutical Approach.

Autor: Azambuja JH; Programa de Pós-Graduação em Biociências, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil. julianahazambuja@hotmail.com., Schuh RS; Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil., Michels LR; Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil., Gelsleichter NE; Programa de Pós-Graduação em Biociências, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil., Beckenkamp LR; Programa de Pós-Graduação em Biociências, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil., Iser IC; Programa de Pós-Graduação em Biociências, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil., Lenz GS; Programa de Pós-Graduação em Biociências, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil., de Oliveira FH; Departamento de Patologia, UFRGS, Porto Alegre, RS, Brazil., Venturin G; Brain Institute of Rio Grande do Sul (BraIns), Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil., Greggio S; Brain Institute of Rio Grande do Sul (BraIns), Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil., daCosta JC; Brain Institute of Rio Grande do Sul (BraIns), Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil., Wink MR; Programa de Pós-Graduação em Biociências, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil., Sevigny J; Département de Microbiologie-Infectiologie et d'Immunologie, Faculté de Médecine, Université Laval, QC, Québec, Canada.; Centre de recherche du CHU de Québec, Université Laval, Québec City, QC, G1V 4G2, Canada., Stefani MA; Departamento de Morfologia, UFRGS, Porto Alegre, RS, Brazil., Battastini AMO; Departamento de Bioquímica, UFRGS, Porto Alegre, RS, Brazil., Teixeira HF; Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil., Braganhol E; Programa de Pós-Graduação em Biociências, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2020 Feb; Vol. 57 (2), pp. 635-649. Date of Electronic Publication: 2019 Aug 12.

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Akademický článek

Adaptive behavior in autism: Minimal clinically important differences on the Vineland-II.

Autor: Chatham CH; F. Hoffmann La Roche, Innovation Center Basel, Hoffmann La Roche, Basel, 4070, Switzerland., Taylor KI; F. Hoffmann La Roche, Innovation Center Basel, Hoffmann La Roche, Basel, 4070, Switzerland., Charman T; Institute of Psychiatry, Psychology & Neuroscience, King's College London, Camberwell, London, SE5 8AF, UK., Liogier D'ardhuy X; F. Hoffmann La Roche, Innovation Center Basel, Hoffmann La Roche, Basel, 4070, Switzerland., Eule E; F. Hoffmann La Roche, Innovation Center Basel, Hoffmann La Roche, Basel, 4070, Switzerland., Fedele A; Autism Speaks, New York, New York, 10016., Hardan AY; Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, 94305-5717., Loth E; Institute of Psychiatry, Psychology & Neuroscience, King's College London, Camberwell, London, SE5 8AF, UK., Murtagh L; F. Hoffmann La Roche, Innovation Center Basel, Hoffmann La Roche, Basel, 4070, Switzerland., Del Valle Rubido M; F. Hoffmann La Roche, Innovation Center Basel, Hoffmann La Roche, Basel, 4070, Switzerland., San Jose Caceres A; Institute of Psychiatry, Psychology & Neuroscience, King's College London, Camberwell, London, SE5 8AF, UK., Sevigny J; F. Hoffmann La Roche, Innovation Center Basel, Hoffmann La Roche, Basel, 4070, Switzerland., Sikich L; Duke Center for Autism and Brain Development, Pavilion East at Lakeview, Durham, North Carolina, 27705., Snyder L; Simons Foundation, New York, New York, 10010., Tillmann JE; Institute of Psychiatry, Psychology & Neuroscience, King's College London, Camberwell, London, SE5 8AF, UK., Ventola PE; Yale Child Study Center, New Haven, CT, 06520., Walton-Bowen KL; Simons Foundation, New York, New York, 10010., Wang PP; Simons Foundation, New York, New York, 10010., Willgoss T; F. Hoffmann La Roche, Innovation Center Basel, Hoffmann La Roche, Basel, 4070, Switzerland., Bolognani F; F. Hoffmann La Roche, Innovation Center Basel, Hoffmann La Roche, Basel, 4070, Switzerland.

Publikováno v: Autism research : official journal of the International Society for Autism Research [Autism Res] 2018 Feb; Vol. 11 (2), pp. 270-283. Date of Electronic Publication: 2017 Sep 21.

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Akademický článek

Optimizing Central Nervous System Drug Development Using Molecular Imaging.

Autor: Hargreaves RJ; Biogen, Cambridge, Massachusetts, USA., Hoppin J; inviCRO, LLC, Boston, Massachusetts, USA., Sevigny J; Biogen, Cambridge, Massachusetts, USA., Patel S; Biogen, Cambridge, Massachusetts, USA., Chiao P; Biogen, Cambridge, Massachusetts, USA., Klimas M; Merck Research Laboratories, West Point, Pennsylvania, USA., Verma A; Biogen, Cambridge, Massachusetts, USA.

Publikováno v: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2015 Jul; Vol. 98 (1), pp. 47-60. Date of Electronic Publication: 2015 May 19.

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Editorial & Opinion

Angiostrongylus cantonensis meningitis presenting with facial nerve palsy.

Autor: Podwall D, Gupta R, Furuya EY, Sevigny J, Resor SR

Publikováno v: Journal of neurology [J Neurol] 2004 Oct; Vol. 251 (10), pp. 1280-1.

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Akademický článek

Impact of therapeutic plasma exchange on cyclosporine kinetics during membrane-based lipid apheresis.

Autor: Balogun RA; Division of Nephrology, Department of Medicine, University of Connecticut Health Center, Farmington, CT 06030, USA. rbalogun@pol.net, Sahadevan M, Sevigny J, Kaplan AA

Publikováno v: American journal of kidney diseases : the official journal of the National Kidney Foundation [Am J Kidney Dis] 2001 Jun; Vol. 37 (6), pp. 1286-9.

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Akademický článek

Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants.

Autor: Sato K; Immunobiology Research Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Balla J, Otterbein L, Smith RN, Brouard S, Lin Y, Csizmadia E, Sevigny J, Robson SC, Vercellotti G, Choi AM, Bach FH, Soares MP

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2001 Mar 15; Vol. 166 (6), pp. 4185-94.

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