Zobrazeno 1 - 10
of 18
pro vyhledávání: '"J J, Ryckewaert"'
Publikováno v:
Journal of Biological Chemistry. 265:9575-9581
We have characterized a monoclonal antibody named D33C, specific for platelet glycoprotein (GP) IIb, which induces fibrinogen binding and platelet aggregation. D33C Fab fragments interact with an average of 44,000 +/- 20,000 sites on resting platelet
Publikováno v:
The Journal of laboratory and clinical medicine. 119(1)
Two peptides corresponding to the sequence of platelet glycoprotein IIIa between serine 27 and arginine 37 were synthesized and used to produce monoclonal antibodies. These two synthetic peptides were identical except for a single substitution at pos
Publikováno v:
Revue des Maladies Respiratoires. 25:1168
Introduction : Durant la derniere decennie, des cellules tumorales capables de s’auto-renouveler indefiniment ont ete qualifiees de cellules souches cancereuses (CSC). Des etudes ont montre que la reparation des lesions epitheliales pulmonaires est
Publikováno v:
Revue des Maladies Respiratoires. 24:1217
Autor:
Annie Andrieux, Gérard Marguerie, J J Ryckewaert, Mark H. Ginsberg, Agnès Chapel, G Hudry-Clergeon, Edward F Plow
Publikováno v:
Journal of Biological Chemistry. 264:9258-9265
Platelet membrane GPIIbIIIa is a member of the family receptors named integrins that recognize RGD sequences in their ligands. GPIIbIIIa interacts with at least three different adhesive ligands: fibrinogen, fibronectin, and von Willebrand factor. The
Autor:
Gérard Marguerie, Annie Andrieux, Edward F Plow, Mark H. Ginsberg, Agnès Chapel, G Hudry-Clergeon, J J Ryckewaert, L. Tranqui, S. Soyez
Publikováno v:
The Journal of Cell Biology
The cytoadhesins represent a group of RGD receptors that belongs to the integrin superfamily of adhesion molecules. Members of this cytoadhesin family include the platelet GPIIb-IIIa and the vitronectin receptors. These glycoproteins share the same b
Autor:
Lucia R. Languino, Adriana Zanetti, J J Ryckewaert, G Marguerie, Annie Andrieux, Pier Carlo Marchisio, M H Charon, Mark H. Ginsberg, E. F. Plow, S Colella
Publikováno v:
Blood. 73:734-742
It has been previously shown that fibrinogen (FG) associates specifically with human umbilical vein and bovine aortic endothelial cells (EC) in culture and induces EC migration. In the present study, we have investigated whether the FG-EC interaction
Autor:
Mark H. Ginsberg, G Marguerie, Alain Duperray, Rolande Berthier, E. F. Plow, E Chagnon, J J Ryckewaert
Publikováno v:
The Journal of Cell Biology
Platelet membrane glycoprotein IIb-IIIa forms a calcium-dependent heterodimer and constitutes the fibrinogen receptor on stimulated platelets. GPIIb is a two-chain protein containing disulfide-linked alpha and beta subunits. GPIIIa is a single chain
Autor:
R F Doolittle, J-J Ryckewaert
Publikováno v:
Oral Presentations.
A synthetic compound, aurin tricarboxylic acid (ATA), in the concentration range of 10-100 nanomoles/ml exhibits the property of significantly shortening the thrombin clotting time of fibrinogen. Upon binding to fibrinogen or fibrin monomers, obtaine
Publikováno v:
XIth International Congress on Thrombosis and Haemostasis.
The involvement of the glycoproteins IIb/IIIa in the binding of fibrinogen to stimulated platelets and in the aggregation of these cells is well documented. Monoclonal antibodies (MoAb) directedagainst these two glycoproteins are useful probes in fun