Výsledky vyhledávání - "J J, Perkins"

Non-Peptide Fibrinogen Receptor Antagonists. 7. Design and Synthesis of a Potent, Orally Active Fibrinogen Receptor Antagonist

Autor: M E, Duggan, A M, Naylor-Olsen, J J, Perkins, P S, Anderson, C T, Chang, J J, Cook, R J, Gould, N C, Ihle, G D, Hartman, J J, Lynch

Publikováno v: Journal of Medicinal Chemistry. 38:3332-3341

The design, synthesis, and pharmacological evaluation of L-734,217, a potent, low-molecular weight, orally active fibrinogen receptor antagonist, is reported. A strategy for producing low-molecular weight inhibitors from the peptide c-[(Ac)CRGDC] A,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::495f8387c2303ffd5cd7ce1418f5c538
https://doi.org/10.1021/jm00017a017

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Nonpeptide alpha(v)beta(3) antagonists. 1. Transformation of a potent, integrin-selective alpha(IIb)beta(3) antagonist into a potent alpha(v)beta(3) antagonist

Autor: M E, Duggan, L T, Duong, J E, Fisher, T G, Hamill, W F, Hoffman, J R, Huff, N C, Ihle, C T, Leu, R M, Nagy, J J, Perkins, S B, Rodan, G, Wesolowski, D B, Whitman, A E, Zartman, G A, Rodan, G D, Hartman

Publikováno v: Journal of medicinal chemistry. 43(20)

Modification of the potent fibrinogen receptor (alpha(IIb)beta(3)) antagonist 1 generated compounds with high affinity for the vitronectin receptor alpha(v)beta(3). Sequential modification of the basic N-terminus of 1 led to the identification of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::27526919826000e62ee0beaa15c67c4c
https://pubmed.ncbi.nlm.nih.gov/11020288

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Nonpeptide glycoprotein IIb/IIIa inhibitors. 8. Antiplatelet activity and oral antithrombotic efficacy of L-734,217

Autor: J J, Cook, M A, Holahan, E A, Lyle, D R, Ramjit, G R, Sitko, M T, Stranieri, R F, Stupienski, A A, Wallace, E L, Hand, J R, Gehret, T, Kothstein, M D, Drag, G Y, McCormick, J J, Perkins, N C, Ihle, M E, Duggan, G D, Hartman, R J, Gould, J J, Lynch

Publikováno v: The Journal of pharmacology and experimental therapeutics. 278(1)

The antiplatelet activity of L-734,217, a nonpeptide platelet GPIIb/IIIa antagonist, was evaluated in the rat, guinea pig and dog. IC50 for inhibition of in vitro platelet aggregation for these species (agonists: adenosine diphosphate, collagen) were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::23bba13711a6a24bbae60b757d5d0136
https://pubmed.ncbi.nlm.nih.gov/8764336

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Akademický článek

Evaluation of the Physiological and Psychological Impact of Ballet Performances Across Age Cohorts: An Observational Uncontrolled Case Study.

Autor: Judge LW; School of Kinesiology, Ball State University, Muncie, IN, USA., Perkins J; Fort Wayne Medical Education Program, Fort Wayne, IN, USA., Wells M; Fort Wayne Medical Education Program, Fort Wayne, IN, USA., Huffman OR; School of Kinesiology, Ball State University, Muncie, IN, USA., Leger A; Department of Applied Physiology School of Kinesiology, University of Louisiana at Lafayette, Lafayette, LA, USA., Fontenot R; Department of Applied Physiology School of Kinesiology, University of Louisiana at Lafayette, Lafayette, LA, USA., Henriksen B; Fort Wayne Medical Education Program, Fort Wayne, IN, USA., Bellar DM; Health & Clinical Sciences, University of North Carolina at Charlotte, Charlotte, NC, USA.

Publikováno v: Journal of dance medicine & science : official publication of the International Association for Dance Medicine & Science [J Dance Med Sci] 2024 Dec; Vol. 28 (4), pp. 240-248. Date of Electronic Publication: 2024 Jun 05.

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Akademický článek

Prioritise safety, optimise success! Return to rugby postpartum.

Autor: Donnelly GM; Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.; Private Practice, Maguiresbridge, N. Ireland, UK., Coltman CE; Research Institute for Sport and Exercise, Faculty of Health, University of Canberra, Canberra, Australian Capital Territory, Australia., Dane K; Discipline of Physiotherapy, Trinity College Dublin School of Medicine, Dublin, Ireland., Elliott-Sale KJ; Department of Sport and Exercise Sciences, Manchester Metropolitan University Institute of Sport, Manchester, UK., Hayman M; Appleton Institute, School of Health, Medical and Applied Sciences, CQUniversity, Rockhampton, Queensland, Australia., McCarthy-Ryan MF; Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK., Perkins J; Women's Welsh Rugby Union, National Centre of Excellence, Wales, UK., Rollins S; Ministry of Defence: Regional Rehabilitation Unit Aldershot, Aldershot, UK., Moore IS; Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.

Publikováno v: European journal of sport science [Eur J Sport Sci] 2024 Jul 08. Date of Electronic Publication: 2024 Jul 08.

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Akademický článek

Comparison of nasal valve dysfunction treatment outcomes for temperature-controlled radiofrequency and functional rhinoplasty surgery: a systematic review and meta-analyses.

Autor: Han JK; Department of Otolaryngology - Head and Neck Surgery, Eastern Virginia Medical School, Norfolk, VA, USA., Perkins J; Independent Clinical Researcher, Sunnyvale, CA, USA., Lerner D; Department of Otolaryngology - Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Yim MT; Department of Otolaryngology - Head and Neck Surgery, Louisiana State University Health, Shreveport, LA, USA., Ishii LE; Department of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA;Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Publikováno v: Rhinology [Rhinology] 2024 Jun 01; Vol. 62 (3), pp. 258-270.

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