Pyrimidine biosynthetic enzymes of Salmonella typhimurium, repressed specifically by growth in the presence of cytidine

Autor: R A Kelln, Gerard A. O'Donovan, K F Foltermann, J J Kinahan

Publikováno v: Journal of Bacteriology. 124:764-774

The repressive effects of exogenous cytidine on growing cells was examined in a specially constructed strain in which the pool sizes of endogenous uridine 5'-diphosphate and uridine 5'-triphosphate cannot be varied by the addition of uracil and/or ur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725d0804bf395e9df2bc39388355c53f
https://doi.org/10.1128/jb.124.2.764-774.1975

Toxicity, elimination, and metabolism of 10-ethyl-10-deazaaminopterin in rats and dogs

Autor: M P, Fanucchi, J J, Kinahan, L L, Samuels, C, Hancock, T C, Chou, D, Niedzwiecki, F, Farag, P M, Vidal, J I, DeGraw, S S, Sternberg

Publikováno v: Cancer research. 47(9)

10-Ethyl-10-deazaaminopterin (10-EdAM) is an antifolate compound with greater therapeutic activity than methotrexate against transplanted tumors in mice. When given weekly for 3 weeks, the 10% lethal dose in rats was 125 mg/kg (i.p.) and in dogs it w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::78b61d37260a559fb7e26cbe7aa039b3
https://pubmed.ncbi.nlm.nih.gov/2436760

Antitumor activity of cytidine dialdehyde and its effects on nucleotide and nucleic acid synthesis

Autor: J J, Kinahan, Z P, Pavelic, R J, Leonard, A, Bloch, G B, Grindey

Publikováno v: Cancer research. 40(3)

Cytidine dialdehyde inhibited the growth of leukemia L1210 cells in culture at a 50% inhibitory concentration of 3.5 X 10(-5) M and, when administered i.p. at 200 mg/kg daily for 5 days, increased the mean survival of L1210 tumor-bearing mice by up t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aa1e2334022e2c2b2fee4b2ec4ccc151
https://pubmed.ncbi.nlm.nih.gov/7471080

Psychosocial, psychiatric and work-related risk factors associated with suicide in Ireland: optimised methodological approach of a case-control psychological autopsy study.

Autor: Arensman E; National Suicide Research Foundation and School of Public Health, College of Medicine and Health, University College Cork, Western Gateway Building, Cork, Ireland. ella.arensman@ucc.ie., Larkin C; Department of Emergency Medicine, University of Massachusetts Medical School, Worcester, 01655, USA., McCarthy J; Diocesan Safeguarding, Kerry, Ireland., Leitao S; School of Public Health, College of Medicine and Health and National Perinatal Epidemiology Centre, Department of Obstetrics and Gynaecology, Cork University Hospital Maternity Hospital, Wilton, Cork, Ireland., Corcoran P; National Suicide Research Foundation and School of Public Health, University College Cork, Western Gateway Building, Cork, Ireland., Williamson E; National Suicide Research Foundation, University College Cork, Western Gateway Building, Cork, Ireland., McAuliffe C; St. Patrick's Mental Health Services, Cork, Ireland., Perry IJ; School of Public Health, College of Medicine and Health, University College Cork, Western Gateway Building, Cork, Ireland., Griffin E; National Suicide Research Foundation, University College Cork, Western Gateway Building, Cork, Ireland., Cassidy EM; Department of Psychiatry and Neurobehavioural Science, University College Cork, Liaison Psychiatry Service, Cork University Hospital, Cork, Ireland., Bradley C; Department of General Practice, University College Cork, Western Gateway Building, Cork, Ireland., Kapur N; Centre for Mental Health and Safety, University of Manchester and Greater Manchester Mental Health NHS Foundation Trust, Manchester, UK., Kinahan J; North Lee Psychiatric Services, Mercy University Hospital, Cork, Ireland., Cleary A; Geary Institute for Public Policy, University College Dublin, Dublin, Ireland., Foster T; Consultant Psychiatrist, Omagh and Fermanagh, Northern Ireland., Gallagher J; School of Public Health, University College Cork, Cork, Ireland., Malone K; School of Medicine, University College Dublin, Dublin, Ireland., Ramos Costa AP; School of Public Health and National Suicide Research Foundation, University College Cork, Cork, Ireland., Greiner BA; School of Public Health, College of Medicine and Health, University College Cork, Cork, Ireland.

Publikováno v: BMC psychiatry [BMC Psychiatry] 2019 Sep 06; Vol. 19 (1), pp. 275. Date of Electronic Publication: 2019 Sep 06.

Suction electrocautery device: an aid to decreasing localized air contamination.

Autor: Kinahan J; Department of Surgery, Division of Urology, University of British Columbia, Vancouver, BC., McLoughlin MG, Taylor C, Snelling CF

Publikováno v: The Canadian journal of urology [Can J Urol] 1998 Mar; Vol. 5 (1), pp. 488-490.