Zobrazeno 1 - 10
of 85
pro vyhledávání: '"J J, Goronzy"'
Publikováno v:
Journal of Clinical Investigation. 94:1134-1140
Macrophages represent a critical component in the inflammatory lesions of giant cell arteritis. By combining immunohistochemistry and in situ hybridization, we have analyzed the functional heterogeneity of tissue-infiltrating macrophages in patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f1181877a616c3bb430a21866e6a4d
https://doi.org/10.1172/jci117428
https://doi.org/10.1172/jci117428
Publikováno v:
The Journal of Immunology. 151:825-836
We have studied the molecular diversity of the allogeneic TCR repertoire specific for the HLA-DR4 variant, DRB1*0404, by analyzing the V beta gene segment usage of CD4+ T cell clones from nine different donors and comparing the V beta repertoire in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8b5782918187fb3aceabd3bc4ed11f4
https://doi.org/10.4049/jimmunol.151.2.825
https://doi.org/10.4049/jimmunol.151.2.825
Publikováno v:
The Journal of Immunology. 148:604-611
Superantigens encoded in the genome or released by bacteria have been identified as potent modulators of the murine immune system. High frequencies of mature or immature T cells are activated or intrathymically deleted when superantigens cross-link M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52f409f5ddd7da81515386eb1d9e5464
https://doi.org/10.4049/jimmunol.148.2.604
https://doi.org/10.4049/jimmunol.148.2.604
Publikováno v:
Autoimmunity. 42(7)
Immune-mediated damage to medium-sized arteries results in wall remodeling with intimal hyperplasia, luminal stenosis and tissue ischemia. In the case of the aorta, vasculitis may result in dissection, aneurysm or rupture. The response-to-injury prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6a9d13ece7d4e7cccc9436673c6c22
https://pubmed.ncbi.nlm.nih.gov/19657775
https://pubmed.ncbi.nlm.nih.gov/19657775
Publikováno v:
Expert opinion on biological therapy. 9(8)
Current treatments for autoimmune disease are hampered by the non-specificity of immunomodulatory interventions, having to accept broad suppression of immunoresponsiveness with potential serious side effects, such as infection or malignancy. The deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c44127e50c990f938b01db84802e7d
https://pubmed.ncbi.nlm.nih.gov/19522557
https://pubmed.ncbi.nlm.nih.gov/19522557
Autor:
C M, Weyand, J J, Goronzy
Publikováno v:
Zeitschrift fur Rheumatologie. 68(2)
Giant cell arteritis (GCA), is a systemic vasculitis which preferentially targets large and medium branches of the upper-body aorta. Typical clinical manifestations result from arterial stenosis/occlusion causing blindness, stroke and aortic arch syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b7fa4fb9ba1ba7ec36ffb385e15c731
https://pubmed.ncbi.nlm.nih.gov/19224227
https://pubmed.ncbi.nlm.nih.gov/19224227
Publikováno v:
The Journal of Immunology. 147:70-78
The self-restriction of Ag-specific T cell responses is interpreted as the result of a positive selection of the individual's T cell specificities for their compatibility with self-MHC molecules. If the T cell receptor (TCR) specificities in any give
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c5eec0cd69ba25e8077b80b0b564a62
https://doi.org/10.4049/jimmunol.147.1.70
https://doi.org/10.4049/jimmunol.147.1.70
Autor:
Konstantinos Aznaouridis, Sarfraz Ali, Nino Kavtaradze, Ibhar Al Mheid, Farah Quyyumi, Muhiddin Ozkor, Saurabh Dhawan, Jonathan Murrow, Riyaz Patel, Connie Weyand, J J Goronzy, R W Alexander, Arshed Quyyumi
Publikováno v:
Circulation. 118
Background: Physical activity is a determinant of cardiovascular performance and a predictor of risk. Levels of progenitor cells that contribute to repair of tissues including the cardiovascular system are modulated by cardiovascular risk factors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d713fa7599d676a02af53840cad2098
https://doi.org/10.1161/circ.118.suppl_18.s_1140
https://doi.org/10.1161/circ.118.suppl_18.s_1140
Autor:
J J, Goronzy, C M, Weyand
Publikováno v:
Current directions in autoimmunity. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb674d2248cfe357cfa85111cfe016fc
https://pubmed.ncbi.nlm.nih.gov/11791462
https://pubmed.ncbi.nlm.nih.gov/11791462
Publikováno v:
Current directions in autoimmunity. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a807909073a7de025afbe8c03a403037
https://pubmed.ncbi.nlm.nih.gov/11791464
https://pubmed.ncbi.nlm.nih.gov/11791464