Zobrazeno 1 - 10
of 42
pro vyhledávání: '"J J, Going"'
Autor:
D F Moffat, J J Going
Publikováno v:
Journal of Clinical Pathology. 49:48-52
AIMS: To reconstruct the arrangement in space of all major ducts and their branches from nipple to periphery of a human breast obtained at necropsy. METHODS: Duct tracing through cleared haematoxylin stained 2 mm sub-gross coronal slices of a complet
Publikováno v:
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 14(12)
It is recognised that colorectal cancer may arise from different genomic instability pathways. There is evidence to suggest that colon and rectal cancers exhibit different clinicopathological features. We examined the relationship between tumour site
Autor:
J J, Going
Publikováno v:
Methods in molecular medicine. 39
Many modern analytical methods require little material, which has made feasible biochemical and molecular analyses of small tissue fragments, even individual cells, by microdissection of histological sections (1,2). Polymerase chain reaction (PCR) ca
Autor:
T Tsuruo, Colin S. McArdle, S. B. Kaye, Gordon C. Wishart, A M McNicol, Jane A. Plumb, J J Going
Publikováno v:
British Journal of Cancer
We have investigated P-glycoprotein (P-gp) expression in samples of primary breast cancer from 29 patients before therapy. We employed immunohistochemical techniques using two monoclonal antibodies (C219 and MRK16) and an indirect alkaline phosphatas
Autor:
B. Dunne, Elizabeth Mallon, A.D. Watters, J M S Bartlett, A. Forsyth, J J Going, R Ainsworth, W Angerson, J Richmond
Background: Her2 (c-erbB-2/neu) overexpression in breast carcinoma predicts response to the anti-Her2 monoclonal antibody, trastuzumab, and is associated with a poor prognosis. When considering patients for trastuzumab treatment, Her2 protein express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d166fd3d62f4e12ba86e0bb8f7db9e
https://europepmc.org/articles/PMC1770743/
https://europepmc.org/articles/PMC1770743/
Autor:
K L Oakley, J J Going
Publikováno v:
Journal of Clinical Pathology. 48:1028-1030
AIM--To investigate histologically the power of specimen slice radiography to record invasive and in situ carcinoma in breast conserving cancer excisions. METHODS--Twenty six cancer excisions were converted into 171 complete tissue slices, which were
Publikováno v:
Scopus-Elsevier
AIMS--To record the histopathological findings associated with intra-arterial injection of Temazepam gel by nine drug misusers. METHODS--Standard histological examination and immunocytochemistry for endothelial markers (factor VIII related antigen, U
Publikováno v:
Journal of oral pathologymedicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 30(10)
Telomerase is detectable in 85% of cancers, but is largely repressed in normal tissues. Human telomerase RNA (hTR) inhibition is a promising anti-cancer strategy, but requires differential expression between malignant and normal tissue.Archival paraf
Publikováno v:
Urologia internationalis. 67(3)
N-acetyltransferase 2 (NAT2), mapped to 8p22, is a polymorphic enzyme which metabolizes aromatic amines. Loss of heterozygosity of 8p22 is associated with an increased risk of bladder cancer. This study evaluated NAT2 and chromosome 8 in sequential t
Autor:
B, Dunne, J J, Going
Publikováno v:
Histopathology. 39(3)
Nuclear grade has equal weight with mitotic index and acinus formation in grading breast cancer, but criteria for its assessment are less well defined. This study examines consistency of nuclear grading in breast cancer and whether improved nuclear g