The insulin sensitizing effect of topiramate involves KATP channel activation in the central nervous system

Autor: C P, Coomans, J J, Geerling, S A A, van den Berg, H C, van Diepen, N, Garcia-Tardón, A, Thomas, J P, Schröder-van der Elst, D M, Ouwens, H, Pijl, P C N, Rensen, L M, Havekes, B, Guigas, J A, Romijn

Publikováno v: British journal of pharmacology. 170(4)

Topiramate improves insulin sensitivity, in addition to its antiepileptic action. However, the underlying mechanism is unknown. Therefore, the present study was aimed at investigating the mechanism of the insulin-sensitizing effect of topiramate both

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8b40fdf12de916de0a9504b3b90084c8
https://pubmed.ncbi.nlm.nih.gov/23957854

Efferent projections of Nps-expressing neurons in the parabrachial region.

Autor: Zhang R; Department of Neurology and Iowa Neuroscience Institute, University of Iowa, Iowa City, Iowa, USA., Huang D; Department of Neurology and Iowa Neuroscience Institute, University of Iowa, Iowa City, Iowa, USA., Gasparini S; Department of Neurology and Iowa Neuroscience Institute, University of Iowa, Iowa City, Iowa, USA., Geerling JC; Department of Neurology and Iowa Neuroscience Institute, University of Iowa, Iowa City, Iowa, USA.

Publikováno v: The Journal of comparative neurology [J Comp Neurol] 2024 Jun; Vol. 532 (6), pp. e25629.

A spatially-resolved transcriptional atlas of the murine dorsal pons at single-cell resolution.

Autor: Nardone S; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., De Luca R; Department of Neurology, Division of Sleep Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, 02215, USA., Zito A; Department of Twin Research & Genetic Epidemiology, King's College London, London, UK.; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.; Department of Genetics, The Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Klymko N; Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA., Nicoloutsopoulos D; UCL Queen Square Institute of Neurology, University College London, London, UK., Amsalem O; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA., Brannigan C; HEAVY.AI, 100 Montgomery St Fl 5, San Francisco, California, 94104, USA., Resch JM; Department of Neuroscience and Pharmacology, University of Iowa, Iowa City, IA, USA.; Fraternal Order of Eagles Diabetes Research Center. University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA., Jacobs CL; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pant D; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA., Veregge M; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA., Srinivasan H; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Grippo RM; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA., Yang Z; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA., Zeidel ML; Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA., Andermann ML; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA., Harris KD; UCL Queen Square Institute of Neurology, University College London, London, UK., Tsai LT; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Arrigoni E; Department of Neurology, Division of Sleep Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, 02215, USA., Verstegen AMJ; Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA. aversteg@bidmc.harvard.edu., Saper CB; Department of Neurology, Division of Sleep Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, 02215, USA. csaper@bidmc.harvard.edu., Lowell BB; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA. blowell@bidmc.harvard.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Mar 04; Vol. 15 (1), pp. 1966. Date of Electronic Publication: 2024 Mar 04.

Sex Differences in CGRP Regulation and Function in the Amygdala in a Rat Model of Neuropathic Pain.

Autor: Presto, Peyton, Neugebauer, Volker

Publikováno v: Frontiers in Molecular Neuroscience; 6/3/2022, Vol. 15, p1-14, 14p

Exendin-4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration.

Autor: Wang, Y^1,2, Parlevliet, E T^1,2,3, Geerling, J J^1,2, Tuin, S J L^1,2, Zhang, H^1,2, Bieghs, V⁴, Jawad, A H M^1,2, Shiri ‐ Sverdlov, R⁴, Bot, I⁵, Jager, S C A⁵, Havekes, L M^1,2,6,7, Romijn, J A^1,2, Willems van Dijk, K^1,2,8, Rensen, P C N^1,2

Publikováno v: British Journal of Pharmacology. Feb2014, Vol. 171 Issue 3, p723-734. 12p.