Zobrazeno 1 - 10
of 292
pro vyhledávání: '"J J, Carr"'
Autor:
R. T. Short, F. Lin, S. Nair, J. G. Terry, J. J. Carr, N. R. Kandula, D. Lloyd-Jones, A. M. Kanaya
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background South Asian individuals have high risk of atherosclerotic cardiovascular disease (ASCVD). Some investigators suggest smaller coronary artery size may be partially responsible. Methods We compared the left anterior descending (LAD)
Externí odkaz:
https://doaj.org/article/4b4f6ae38b224f8194e1ea1fc54f7bf6
Publikováno v:
Pathogens, Vol 13, Iss 1, p 74 (2024)
The complement system (CS) contributes to the initial containment of viral and bacterial pathogens and clearance of dying cells in circulation. We previously reported mice deficient in complement component 3 (C3KO mice) were more sensitive than wild-
Externí odkaz:
https://doaj.org/article/150aead7fe4a47b3adec06bbb3b0b800
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Effective experimental prophylactic vaccines against viral pathogens such as herpes simplex virus type 1 (HSV-1) have been shown to protect the host through T and/or B lymphocyte-driven responses. Previously, we found a live-attenuated HSV-1
Externí odkaz:
https://doaj.org/article/9ec4704592534406b324b321ac6f559f
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Ocular pathology is often associated with acute herpes simplex virus (HSV)-1 infection of the cornea in mice. The present study was undertaken to determine the role of early T lymphocyte activation 1 protein or osteopontin (OPN) in corneal inflammati
Externí odkaz:
https://doaj.org/article/497db22ae50a486c9dcdfa6d91a445ad
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Corneal transparency is an essential characteristic necessary for normal vision. In response to microbial infection, the integrity of the cornea can become compromised as a result of the inflammatory response and the ensuing tissue pathology
Externí odkaz:
https://doaj.org/article/181959dcb960480a9c1dd4c4285e6486
Publikováno v:
Viruses, Vol 14, Iss 3, p 589 (2022)
Tripartite-motif 21 (TRIM21) is thought to regulate the type I interferon (IFN) response to virus pathogens and serve as a cytosolic Fc receptor for immunoglobulin. Since herpes simplex virus (HSV)-1 is sensitive to type I IFN and neutralizing antibo
Externí odkaz:
https://doaj.org/article/7431e9c4f2124a2bbbc05116bc9490cc
Publikováno v:
Pathogens, Vol 10, Iss 11, p 1470 (2021)
Vaccines to viral pathogens in experimental animal models are often deemed successful if immunization enhances resistance of the host to virus challenge as measured by cumulative survival, reduction in virus replication and spread and/or lessen or el
Externí odkaz:
https://doaj.org/article/7498f53bc1b24c5f9bfa10955a521893
Autor:
Jami M. Gurley, Grzegorz B. Gmyrek, Elizabeth A. Hargis, Gail A. Bishop, Daniel J. J. Carr, Michael H. Elliott
Publikováno v:
Cells, Vol 10, Iss 8, p 2068 (2021)
Uncontrolled inflammation is associated with neurodegenerative conditions in central nervous system tissues, including the retina and brain. We previously found that the neural retina (NR) plays an important role in retinal immunity. Tumor necrosis f
Externí odkaz:
https://doaj.org/article/f16e54e8f5a548238f3c95ace6979ccb
Autor:
Chandra M. Menendez, Daniel J. J. Carr
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-11 (2017)
Abstract Background Herpes simplex virus 1 (HSV-1) infection can result in a life-threatening condition known as herpes simplex encephalitis (HSE). Trafficking patterns by which the virus reaches the central nervous system (CNS) following ocular infe
Externí odkaz:
https://doaj.org/article/508471d0ab4f4aabaf64adc10bbdbdd9
Autor:
Duke Appiah, Charles P. Quesenberry, Stephen Sidney, J J Carr, David R. Jacobs, Cora E. Lewis, James M. Shikany, Erica P. Gunderson, Myron D. Gross
Publikováno v:
J Clin Endocrinol Metab
Background Lactation is associated with lower risks for cardiovascular disease in women. Organ-related adiposity, which plays significant roles in the development of cardiometabolic diseases, could help explain this observation. We evaluated the asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e293841dbc0a5ef3d9598749e226aa4b
https://doi.org/10.1210/clinem/dgaa980
https://doi.org/10.1210/clinem/dgaa980