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Autor: J van der Kaa, G J Platenburg, J D Leung, F R Pieper, D O Co, S Hengst, Anita Borowski, F R Jirik, Carl Perez, J I Drayer

Publikováno v: Chromosome Research. 8:183-191

We have generated transgenic mice by pronuclear microinjection of a murine satellite DNA-based artificial chromosome (SATAC). As 50% of the founder progeny were SATAC-positive, this demonstrates that SATAC transmission through the germline had occurr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c58a298ee7a46ebf48e5498066a25c97
https://doi.org/10.1023/a:1009206926548

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Generation of transgenic mice and germline transmission of a mammalian artificial chromosome introduced into embryos by pronuclear microinjection

Autor: D O, Co, A H, Borowski, J D, Leung, J, van der Kaa, S, Hengst, G J, Platenburg, F R, Pieper, C F, Perez, F R, Jirik, J I, Drayer

Publikováno v: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology. 8(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9f7da0a21a69edb754e2dcda16203e2a
https://pubmed.ncbi.nlm.nih.gov/10841045

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Mammalian artificial chromosome pilot production facility: large-scale isolation of functional satellite DNA-based artificial chromosomes

Autor: G, deJong, A H, Telenius, H, Telenius, C F, Perez, J I, Drayer, G, Hadlaczky

Publikováno v: Cytometry. 35(2)

A pilot production facility has been established to isolate mammillian artificial chromosomes at high purity by using flow cytometric techniques. Dicentric chromosomes have been generated by the targeted amplification of pericentric heterochromatic a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::79780980c81674dd270119dec51e293f
https://pubmed.ncbi.nlm.nih.gov/10554168

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Stability of a functional murine satellite DNA-based artificial chromosome across mammalian species

Autor: H, Telenius, A, Szeles, J, Keresö, E, Csonka, T, Praznovszky, S, Imreh, A, Maxwell, C F, Perez, J I, Drayer, G, Hadlaczky

Publikováno v: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology. 7(1)

A 60-Mb murine chromosome consisting of murine pericentric satellite DNA and two bands of integrated marker and reporter genes has been generated de novo in a rodent/human hybrid cell line (mM2C1). This prototype mammalian artificial chromosome platf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8976562437ce3fc1ebfb87690c9fabfa
https://pubmed.ncbi.nlm.nih.gov/10219727

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Gene Therapy in Malignancies: Development and Clinical Applications of Autologous Tumour Vaccines

Autor: J. I. Drayer

Publikováno v: Cytokines and Growth Factors in Blood Transfusion ISBN: 9781461284352

Various applications of therapeutically active cancer vaccines have recently been reviewed by Subiza et al. [1]. In their opinion, concepts and tools related to such therapies are more clear than ever before and clinical results are encouraging. Acco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c63dac411c85a2d6fdbe48ce7a66917e
https://doi.org/10.1007/978-1-4613-1137-9_13

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