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The causative agent of ovine footrot, the gram-negative anaerobe Dichelobacter nodosus, produces polar type IV fimbriae, which are the major protective antigens. The D. nodosus genes fimN, fimO, and fimP are homologs of the Pseudomonas aeruginosa fim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1ee0700b25f4fe36ffec4655d3353ff8
https://pubmed.ncbi.nlm.nih.gov/9423871

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Isolation of alpha-toxin, theta-toxin and kappa-toxin mutants of Clostridium perfringens by Tn916 mutagenesis

Autor: M M, Awad, J I, Rood

Publikováno v: Microbial pathogenesis. 22(5)

Clostridium perfringens is the causative agent of clostridial myonecrosis or gas gangrene and mediates infection and disease by producing numerous extracellular toxins, including alpha-toxin, theta-toxin and kappa-toxin. Tn916-mutagenesis was used to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9c4277df83c8075cbfe13cc0deb4b11a
https://pubmed.ncbi.nlm.nih.gov/9160297

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A multiple site-specific DNA-inversion model for the control of Omp1 phase and antigenic variation in Dichelobacter nodosus

Autor: E K, Moses, R T, Good, M, Sinistaj, S J, Billington, C J, Langford, J I, Rood

Publikováno v: Molecular microbiology. 17(1)

The molecular cloning and sequence analysis of four structurally variant linked genes (omp1A,B,C,D) that encode the major outer membrane protein of Dichelobacter nodosus strain VCS1001 are described. The isolation of rearranged copies of omp1A and om

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b4324128d56d4d9ba08070af2d662f15
https://pubmed.ncbi.nlm.nih.gov/7476204

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Production of chorismate mutase-prephenate dehydrogenase by a strain of Escherichia coli carrying a multicopy, tyrA plasmid. Isolation and properties of the enzyme

Autor: S B, Bhosale, J I, Rood, M K, Sneddon, J F, Morrison

Publikováno v: Biochimica et biophysica acta. 717(1)

A multicopy plasmid that contains the tyrosine operon has been used to transform strains of Escherichia coli K-12. The resultant strains yielded levels of chorismate mutase-prephenate dehydrogenase that were up to 5000-fold higher than that given by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c56634471375ef507dfc32880eae384
https://pubmed.ncbi.nlm.nih.gov/7049251

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Environmental Response and Autoregulation of Clostridium difficile TxeR, a Sigma Factor for Toxin Gene Expression

Autor: Lisa Barroso, Pauline Howarth, Julian I. Rood, Tracy D. Wilkins, Nagraj Mani, Dena Lyras, Bruno Dupuy, Abraham L. Sonenshein

Publikováno v: Journal of Bacteriology
Journal of Bacteriology, American Society for Microbiology, 2002, 184 (21), pp.5971-5978. ⟨10.1128/jb.184.21.5971-5978.2002⟩
Monash University
Journal of Bacteriology, 2002, 184 (21), pp.5971-5978. ⟨10.1128/jb.184.21.5971-5978.2002⟩

TxeR, a sigma factor that directs Clostridium difficile RNA polymerase to recognize the promoters of two major toxin genes, was shown to stimulate its own synthesis. Whether expressed in C. difficile , Clostridium perfringens , or Escherichia coli ,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6adc4b9e2e88ae49658315a8c7c3ef5
https://doi.org/10.1128/jb.184.21.5971-5978.2002

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