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pro vyhledávání: '"J I, Bell"'
There is a polygenic component to rheumatoid arthritis (RA) in addition to the known association with HLA-DR4. It has previously been shown in another autoimmune disease (type I diabetes mellitus) that a gene on chromosome 11p can act with HLA-DR4 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e73e8898e1ac739410409bd9be6a2df
https://doi.org/10.1136/ard.51.11.1250
https://doi.org/10.1136/ard.51.11.1250
Autor:
J. M. Farrant, Michael Bunce, Derek P. Jewell, C Julier, J I Bell, Kenneth I. Welsh, J Satsangi
BACKGROUND: Despite strong evidence implicating immune dysfunction and genetic predisposition in the pathogenesis of the chronic inflammatory bowel diseases Crohn's disease and ulcerative colitis, the importance of the genes of the major histocompati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533ab1471502ac39b5ddba339158f59d
https://doi.org/10.1016/s0140-6736(96)90734-5
https://doi.org/10.1016/s0140-6736(96)90734-5
Autor:
Se E. Marshall, Michael Bunce, Pj J. Hunt, J I Bell, Ap P. Weetman, Ja A. H. Wass, Ki I. Welsh
Publikováno v:
Clinical Endocrinology. 55:491-499
OBJECTIVES Associations between autoimmune thyroid disease and antigens of the major histocompatibility complex (MHC) have long been recognized. Graves' disease (GD) is associated with the histocompatibility leucocyte antigen (HLA) haplotype A*01-B*0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8571a4179e8c1e307c2a5edaae1321e6
https://doi.org/10.1046/j.1365-2265.2001.01356.x
https://doi.org/10.1046/j.1365-2265.2001.01356.x
Publikováno v:
The Journal of Immunology. 155:5046-5056
CD8+CD57+ lymphocytes from normal peripheral blood are divided into T cells expressing high levels of CD8 and NK cells expressing low levels of surface CD8. Increased numbers of CD8highCD57+ T cells correlate with previous exposure to human cytomegal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bc82ac3f92cdb66a5df63e9cd542d4c
https://doi.org/10.4049/jimmunol.155.10.5046
https://doi.org/10.4049/jimmunol.155.10.5046
Autor:
J I, Bell
Publikováno v:
Current Opinion in Genetics & Development. 3:466-469
Considerable success is now being achieved in defining genetic susceptibility loci in polygenic disease. In particular, new susceptibility loci have been identified in hypertension, type I and type II diabetes, asthma and malaria infection. The appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88da106708bfd4e08e38729e8731722a
https://doi.org/10.1016/0959-437x(93)90121-5
https://doi.org/10.1016/0959-437x(93)90121-5
Autor:
C. Julier, R. N. Hyer, J. Davies, F. Merlin, P. Soularue, L. Briant, G. Cathelineau, I. Deschamps, J. I. Rotter, P. Froguel, C. Boitard, J. I. Bell, G. M. Lathrop
Publikováno v:
Nature. 354:155-159
A class of alleles at the VNTR (variable number of tandem repeat) locus in the 5' region of the insulin gene (INS) on chromosome 11p is associated with increased risk of insulin-dependent diabetes mellitus (IDDM), but family studies have failed to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59aaedee8f6c4b23098fbcbbcc62cb0
https://doi.org/10.1038/354155a0
https://doi.org/10.1038/354155a0
Publikováno v:
Clinical endocrinology. 55(4)
Associations between autoimmune thyroid disease and antigens of the major histocompatibility complex (MHC) have long been recognized. Graves' disease (GD) is associated with the histocompatibility leucocyte antigen (HLA) haplotype A*01-B*0801-DRB1*03
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4d79e571cf3624d98254959b060c049
https://pubmed.ncbi.nlm.nih.gov/11678832
https://pubmed.ncbi.nlm.nih.gov/11678832
Autor:
S, Tafuro, U C, Meier, P R, Dunbar, E Y, Jones, G T, Layton, M G, Hunter, J I, Bell, A J, McMichael
Publikováno v:
European journal of immunology. 31(2)
Engineered MHC-peptide targets capable of inducing recognition by CTL may prove useful in designing vaccines for infectious disease and cancer. We tested whether peptides directly linked to beta2-microglobulin (beta2m) could complex with human HLA cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2d1bf828602548e3eec3744dd61c643
https://pubmed.ncbi.nlm.nih.gov/11180108
https://pubmed.ncbi.nlm.nih.gov/11180108
Publikováno v:
Tissue Antigens. 40:264-266
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fe420569548bc7f8c8b006a47664006
https://doi.org/10.1111/j.1399-0039.1992.tb02056.x
https://doi.org/10.1111/j.1399-0039.1992.tb02056.x
Autor:
John A.H. Wass, Sara E. Marshall, Anthony P. Weetman, J I Bell, Penny J. Hunt, Kenneth I. Welsh
Publikováno v:
The Journal of clinical endocrinology and metabolism. 85(5)
Susceptibility to the autoimmune thyroid diseases, Graves’ disease (GD) and autoimmune hypothyroidism (AIH), depends on a complex interaction between environmental and genetic factors. The human leukocyte antigen and cytotoxic T lymphocyte-associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0524867ae887d495c6bdcec0f1ce2d
http://ora.ox.ac.uk/objects/uuid:8bbdebf6-27fa-405e-898f-b36a766b6065
http://ora.ox.ac.uk/objects/uuid:8bbdebf6-27fa-405e-898f-b36a766b6065