Zobrazeno 1 - 10
of 2 108
pro vyhledávání: '"J Hope"'
Publikováno v:
HemaSphere, Vol 8, Iss 8, Pp n/a-n/a (2024)
Abstract Strict control over hematopoietic stem cell decision making is essential for healthy life‐long blood production and underpins the origins of hematopoietic diseases. Acute myeloid leukemia (AML) in particular is a devastating hematopoietic
Externí odkaz:
https://doaj.org/article/bf6d0938780a4c0ab6b271858aea0e8d
Publikováno v:
International Journal for Equity in Health, Vol 23, Iss 1, Pp 1-15 (2024)
Abstract Background Partnerships between Higher Education Institutions (HEIs) in the global north and south have commonly been used as a vehicle to drive global health research and initiatives. Among these initiatives, include health system strengthe
Externí odkaz:
https://doaj.org/article/05284e959b5c4700aa7238a55fa73ec9
Autor:
Jinhee Kim, Deepanwita Bose, Mariluz Araínga, Muhammad R. Haque, Christine M. Fennessey, Rachel A. Caddell, Yanique Thomas, Douglas E. Ferrell, Syed Ali, Emanuelle Grody, Yogesh Goyal, Claudia Cicala, James Arthos, Brandon F. Keele, Monica Vaccari, Ramon Lorenzo-Redondo, Thomas J. Hope, Francois Villinger, Elena Martinelli
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract HIV-1 persistence during ART is due to the establishment of long-lived viral reservoirs in resting immune cells. Using an NHP model of barcoded SIVmac239 intravenous infection and therapeutic dosing of anti-TGFBR1 inhibitor galunisertib (LY2
Externí odkaz:
https://doaj.org/article/fbe3b5ac6da84f6e995899f2ef2ce0bd
Publikováno v:
PRX Quantum, Vol 5, Iss 3, p 030303 (2024)
The ability of quantum states to be in superposition is one of the key features that sets them apart from the classical world. This “coherence” is rigorously quantified by resource theories, which aim to understand how such properties may be expl
Externí odkaz:
https://doaj.org/article/28edb5f610e74547bcbe89f9d06088da
This open access book offers an overview of the beautiful, powerful, and dynamic array of opportunities to promote health through the arts from theoretical, methodological, pedagogical, and critical perspectives. This is the first-known text to conne
Autor:
STEIN, J. HOPE
Publikováno v:
Ploughshares, 2022 Apr 01. 48(1), 147-147.
Externí odkaz:
https://www.jstor.org/stable/27163138
Autor:
Sadia Samer, Yanique Thomas, Mariluz Araínga, Crystal Carter, Lisa M. Shirreff, Muhammad S. Arif, Juan M. Avita, Ines Frank, Michael D. McRaven, Christopher T. Thuruthiyil, Veli B. Heybeli, Meegan R. Anderson, Benjamin Owen, Arsen Gaisin, Deepanwita Bose, Lacy M. Simons, Judd F. Hultquist, James Arthos, Claudia Cicala, Irini Sereti, Philip J. Santangelo, Ramon Lorenzo-Redondo, Thomas J. Hope, Francois J. Villinger, Elena Martinelli
Publikováno v:
JCI Insight, Vol 7, Iss 21 (2023)
TGF-β plays a critical role in maintaining immune cells in a resting state by inhibiting cell activation and proliferation. Resting HIV-1 target cells represent the main cellular reservoir after long-term antiretroviral therapy (ART). We hypothesize
Externí odkaz:
https://doaj.org/article/d91bfe3dac314d9ab922f0f232b2155b
Autor:
LaTonya D Williams, Xiaoying Shen, Sheetal S Sawant, Siriwat Akapirat, Lindsay C Dahora, Matthew Zirui Tay, Sherry Stanfield-Oakley, Saintedym Wills, Derrick Goodman, DeAnna Tenney, Rachel L Spreng, Lu Zhang, Nicole L Yates, David C Montefiori, Michael A Eller, David Easterhoff, Thomas J Hope, Supachai Rerks-Ngarm, Punnee Pittisuttithum, Sorachai Nitayaphan, Jean-Louis Excler, Jerome H Kim, Nelson L Michael, Merlin L Robb, Robert J O'Connell, Nicos Karasavvas, Sandhya Vasan, Guido Ferrari, Georgia D Tomaras, RV305 study team
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011359 (2023)
The modestly efficacious HIV-1 vaccine regimen (RV144) conferred 31% vaccine efficacy at 3 years following the four-shot immunization series, coupled with rapid waning of putative immune correlates of decreased infection risk. New strategies to incre
Externí odkaz:
https://doaj.org/article/e0502dca070d4a5f86962367ed6a51ba
Autor:
Lina Liu, Ana Vujovic, Nandan P. Deshpande, Shashank Sathe, Govardhan Anande, He Tian Tony Chen, Joshua Xu, Mark D. Minden, Gene W. Yeo, Ashwin Unnikrishnan, Kristin J. Hope, Yu Lu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Leukemic stem cells (LSCs) drive chemoresistance and relapse in acute myeloid leukemia. Here, the authors show that the splicing factor RBM17 supports LSCs through avoiding nonsense-mediated decay of pro-leukaemic factors such as the translation init
Externí odkaz:
https://doaj.org/article/85c36ded2db34489ade4dbffb3dc816b
Autor:
Usama Nasir, Tayyab Ali Waheed, Keerat Rai Ahuja, Charnjeet Singh Sandhu, Muhammad Ameen, Earl J. Hope
Publikováno v:
The Egyptian Heart Journal, Vol 74, Iss 1, Pp 1-7 (2022)
Abstract Background Anemia is a known risk factor for ischemic heart disease and serves as an independent predictor of major adverse cardiovascular events (MACE) in patients with acute coronary syndrome (ACS). This meta-analysis pools data from rando
Externí odkaz:
https://doaj.org/article/157c43ecd9104a8aa0898fc8ba748fb3