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Akademický článek
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Autor:
R. Byrne, Hans P. Kiener, B. E. M. Bachmann, Wolfgang Holnthoner, I Olmos Calvo, J Holinka, S. Schobesberger, Ariane Fischer, Peter Ertl, Reinhard Windhager, Stefan Toegel, Sarah Spitz, Heinz Redl, Florian Sevelda, Mario Rothbauer, E. Reihs
Rheumatoid arthritis is characterised by a progressive, intermittent inflammation at the synovial membrane, which ultimately leads to the destruction of the synovial joint. The synovial membrane, which is the joint capsule’s inner layer, is lined w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99d47d72289e4a0a7c2eb12362255781
https://doi.org/10.1101/2021.02.19.431936
https://doi.org/10.1101/2021.02.19.431936
Autor:
J. Holinka
Publikováno v:
Zeitschrift für Rheumatologie. 77:896-898
Der Trend zeigt bei Rheumapatienten tendenziell einen Ruckgang an gelenkerhaltenden Operationen wie Synovektomie und Gelenkersatzoperationen mit Huftprothesen. Dies ist v. a. auf die systemische Therapie mit den bDMARDS („biological disease-modifyi
Autor:
Giulio Superti-Furga, Isabel Olmos Calvo, J Holinka, K Dalwigk, Florian Sevelda, M Bonelli, Guenter Steiner, Alexander Platzer, Thomas Karonitsch, Josef S. Smolen, Hans P. Kiener, Silvia Hayer, Birgit Niederreiter, Thomas Pap
Publikováno v:
Abstracts.
Career situation of first and presenting author Young investigator. Introduction Rheumatoid arthritis (RA) is an autoimmune disease, which is characterized by persistent, synovial inflammation. Major drivers of synovial inflammation are cytokines and
Autor:
J, Holinka
Publikováno v:
Zeitschrift fur Rheumatologie. 77(10)
There is a trend towards a reduction in joint-preserving hip surgery, such as synovectomy and total hip joint replacement in rheumatic patients. This is mostly due to the success of biological disease-modifying antirheumatic drugs (bDMARD) in systemi
Autor:
Farideh Alasti, Hans P. Kiener, Michael Bonelli, Birgit Niederreiter, Guenter Steiner, Peter Ertl, Ruth A. Byrne, Josef S Smolen, J Holinka, I Olmos Calvo, Thomas Karonitsch
Publikováno v:
Poster presentations.
Introduction The synovium demonstrates a distinct cellular structure with a densely packed synovial lining layer that sits on top of a loosely organised sublining layer. In rheumatoid arthritis (RA), this tissue hosts the inflammatory reaction and un
Autor:
Alexander Platzer, Peter Ertl, Ruth A. Byrne, H-P Kiener, L Lovicar, V Zheden, Felix Kartnig, Guenter Steiner, J Holinka, I Olmos Calvo, Josef S Smolen
Publikováno v:
Poster presentations.
Introduction The synovium is primarily built by fibroblast-like-synoviocytes (FLS). In the healthy synovium FLS form a complex tissue network via long-distance intercellular connexions (nanotubes). Using a 3D synovial micromass culture system, our pr
Autor:
Adelheid Korb-Pap, Florian Sevelda, Guenter Steiner, Josef S Smolen, Ruth A. Byrne, Thomas Karonitsch, J Holinka, Hans P. Kiener, Birgit Niederreiter, Denise Beckmann, Thomas Pap, K Dalwigk
Publikováno v:
Poster Presentations.
Background Emerging evidence suggests that fibroblast-like synoviocytes (FLS) are key effector cells in rheumatoid arthritis (RA) and research into the mechanisms defining FLS activity in RA indicate that cytokines secreted by leukocytes play a cruci
Autor:
J, Holinka, R, Windhager
Publikováno v:
Der Orthopade. 45(4)
Infections of prosthetic joints with biofilm-forming pathogens are one of the most devastating complications for patients and surgeons. Although the incidence is low they result in massive restrictions in the quality of life and mobility for patients