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Akademický článek

Reproducibility of the Gartland Classification for Supracondylar Humeral Fractures in Children

Autor: J Heal, M Bould, J Livingstone, N Blewitt, AW Blom

Publikováno v: Journal of Orthopaedic Surgery, Vol 15 (2007)

Purpose. To evaluate the intra- and inter-observer reproducibility of the Gartland radiographic classification for supracondylar humeral fractures in children. Methods. Anteroposterior and lateral radiographs of 50 supracondylar humeral fractures in

Externí odkaz: https://doaj.org/article/79d83beec8894f29b038f30143b26782

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Akademický článek

A critical assessment of the abuse, dependence and associated safety risks of naturally occurring and synthetic cannabinoids

Autor: David J. Heal, Jane Gosden, Sharon L. Smith

Publikováno v: Frontiers in Psychiatry, Vol 15 (2024)

Various countries and US States have legalized cannabis, and the use of the psychoactive1 and non-psychoactive cannabinoids is steadily increasing. In this review, we have collated evidence from published non-clinical and clinical sources to evaluate

Externí odkaz: https://doaj.org/article/351461b43e3f4fb2873ef3a0c74eab5b

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Psychedelic drug abuse potential assessment for new drug applications and controlled substance scheduling: A United States perspective

Autor: Jack E. Henningfield, Judy Ashworth, David J. Heal, Sharon L. Smith

Publikováno v: Journal of Psychopharmacology. 37:33-44

Background: Psychedelics are an increasingly active area of research and pharmaceutical development. This includes abuse potential assessment to better understand their pharmacological mechanisms and effects and guide controlled substance regulation.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab11ffabd6eb128f3d875510e9d4847
https://doi.org/10.1177/02698811221140004

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Preclinical Assessment of the Abuse Potential of Purified Botanical Cannabidiol: Self-Administration, Drug Discrimination, and Physical Dependence

Autor: R A, Gray, D J, Heal, D R, Maguire, L R, Gerak, M A, Javors, S, Smith, C P, France

Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 382:54-65

Cannabidiol (CBD) is a constituent of the cannabis plant with a diverse array of pharmacological activities as well as potential therapeutic uses. An oral formulation of CBD (Epidiolex in the US; Epidyolex in Europe) is approved for treating seizures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163b61e061db309f4b98cd1de48b364c
https://doi.org/10.1124/jpet.121.000988

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Cut-Up Transmediality: From Text to Image

Autor: Benjamin J. Heal

This chapter explores the visual aspects of William S. Burroughs and Brion Gysin’s “cut-up” project as specifically “transmedial,” rather than “intermedial” by critically examining their exploration of this largely aleatory collage tech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd80f143e6539ec88b2da3525f108b2
https://mts.intechopen.com/articles/show/title/cut-up-transmediality-from-text-to-image

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Akademický článek

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Contrasting effects of the α7 nicotinic receptor antagonist methyllycaconitine in different rat models of heroin reinstatement

Autor: David J Heal, Josephine Palandri, Susan Wonnacott, Christopher P Bailey, Sharon L Smith

Publikováno v: Journal of Psychopharmacology (Oxford, England)

Background: α7 Nicotinic acetylcholine receptors are implicated in the reinstatement of drug-seeking, an important component of relapse. We showed previously that the α7 nicotinic acetylcholine receptor antagonist, methyllycaconitine, specifically

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a65710188bda0408584e0f48d176d9
https://doi.org/10.1177/0269881121991570

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New Drugs to Treat ADHD: Opportunities and Challenges in Research and Development

Autor: David J, Heal, Jane, Gosden, Sharon L, Smith

Publikováno v: Current topics in behavioral neurosciences. 57

Since the landmark MTA (Multimodal Treatment of ADHD) trial unequivocally demonstrated the efficacy of methylphenidate, catecholaminergic drugs, especially stimulants, have been the therapeutic mainstay in treatment of Attention-Deficit Hyperactivity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8ef1f48b557adf503d6055180f09e72f
https://pubmed.ncbi.nlm.nih.gov/35507283

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Psychedelic drug abuse potential assessment research for new drug applications and Controlled Substances Act scheduling

Autor: Jack E. Henningfield, Marion A. Coe, Roland R. Griffiths, Sean J. Belouin, Ann Berger, Allison R. Coker, Sandra D. Comer, David J. Heal, Peter S. Hendricks, Charles D. Nichols, Frank Sapienza, Frank J. Vocci, Farah Z. Zia

Publikováno v: Neuropharmacology. 218

New medicines containing classic hallucinogenic and entactogenic psychedelic substance are under development for various psychiatric and neurological disorders. Many of these, including psilocybin, lysergic acid diethylamide (LSD), and 3,4-methylened

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ac062d4ee3223273134a1958028fec
https://pubmed.ncbi.nlm.nih.gov/35987353

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Beat Hotel

Autor: Benjamin J. Heal

The plaque celebrating the writers who resided at the Beat Hotel, 9 Rue Git le Coeur in Paris, was unveiled in 2009 to mark the 50th anniversary of William Burroughs’ Naked Lunch, with Harold Norse’s name added almost as afterthought. At the even

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5241439040f3ef9aa68b1ad949835d0d
https://doi.org/10.3828/liverpool/9781638040163.003.0012

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