Zobrazeno 1 - 10
of 802
pro vyhledávání: '"J Hathaway"'
Autor:
Randy F. Ko, Oliver Q. C. Davidson, Michael A. Ahmed, Ross M. Clark, Jacquelyn S. Brandenburg, Vernon S. Pankratz, Geetanjali Sharma, Helen J. Hathaway, Eric R. Prossnitz, Thomas R. Howdieshell
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Estrogens regulate numerous physiological and pathological processes, including wide-ranging effects in wound healing. The effects of estrogens are mediated through multiple estrogen receptors (ERs), including the classical nuclear ERs (ERα
Externí odkaz:
https://doaj.org/article/32db7899e1c44eefb26f63fcaac26534
Autor:
Nicholas J Hathaway, Isaac E Kim, Neeva WernsmanYoung, Sin Ting Hui, Rebecca Crudale, Emily Y Liang, Christian P Nixon, David Giesbrecht, Jonathan J Juliano, Jonathan B Parr, Jeffrey A Bailey
Publikováno v:
eLife, Vol 13 (2024)
Most malaria rapid diagnostic tests (RDTs) detect Plasmodium falciparum histidine-rich protein 2 (PfHRP2) and PfHRP3, but deletions of pfhrp2 and phfrp3 genes make parasites undetectable by RDTs. We analyzed 19,313 public whole-genome-sequenced P. fa
Externí odkaz:
https://doaj.org/article/89d44ce7c6f34b10a4fe909c365032d5
Autor:
Ying-An Chen, Eric Neubauer Vickers, Andres Aranda-Diaz, Maxwell Murphy, Inna Gerlovina, Francois Rerolle, Emily Dantzer, Bouasy Hongvanthong, Hsiao-Han Chang, Andrew A Lover, Nicholas J Hathaway, Adam Bennett, Bryan Greenhouse
Publikováno v:
PLoS Pathogens, Vol 20, Iss 9, p e1012194 (2024)
While there has been significant progress in controlling falciparum malaria in the Lao People's Democratic Republic (PDR), sporadic cases persist in southern provinces where the extent and patterns of transmission remain largely unknown. To assess pa
Externí odkaz:
https://doaj.org/article/3eadb68c5d2e421daefc89bcc6c04c01
Autor:
Janine Lux, Lucía Sánchez García, Patricia Chaparro Fernández, Laura Laloli, Manon F. Licheri, Clement Gallay, Peter W. M. Hermans, Nicholas J. Croucher, Jan-Willem Veening, Ronald Dijkman, Daniel Straume, Lucy J. Hathaway
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Klebsiella pneumoniae releases the peptides AKTIKITQTR and FNEMQPIVDRQ, which bind the pneumococcal proteins AmiA and AliA respectively, two substrate-binding proteins of the ABC transporter Ami-AliA/AliB oligopeptide permease. Exposure to t
Externí odkaz:
https://doaj.org/article/4249019f61924d459a99bbb220c27535
Autor:
Janine Lux, Hannah Portmann, Lucía Sánchez García, Maria Erhardt, Lalaina Holivololona, Laura Laloli, Manon F. Licheri, Clement Gallay, Robert Hoepner, Nicholas J. Croucher, Daniel Straume, Jan-Willem Veening, Ronald Dijkman, Manfred Heller, Denis Grandgirard, Stephen L. Leib, Lucy J. Hathaway
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Treatment of pneumococcal infections is limited by antibiotic resistance and exacerbation of disease by bacterial lysis releasing pneumolysin toxin and other inflammatory factors. We identified a previously uncharacterized peptide in the Kle
Externí odkaz:
https://doaj.org/article/2a2b48dedc9249f1b222be17efc91b1a
Autor:
Denis M. Tebit, Gabrielle Nickel, Richard Gibson, Myriam Rodriguez, Nicolas J. Hathaway, Katie Bain, Angel L. Reyes-Rodriguez, Pascal Ondoa, Jonathan L. Heeney, Yue Li, Jennifer Bongorno, David Canaday, David McDonald, Jeffrey A. Bailey, Eric J. Arts
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104965- (2024)
Summary: Background: Simian immunodeficiency viruses (SIV) have been jumping between non-human primates in West/Central Africa for thousands of years and yet, the HIV-1 epidemic only originated from a primate lentivirus over 100 years ago. Methods: T
Externí odkaz:
https://doaj.org/article/2775faec513a4e519cd82b6bb90a918f
Autor:
Joel P. Werren, Nadja Mostacci, Ilche Gjuroski, Lalaina Holivololona, Lukas J. Troxler, Lucy J. Hathaway, Julien Furrer, Markus Hilty
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundThe polysaccharide capsule of Streptococcus pneumoniae plays a major role in virulence, adherence to epithelial cells, and overall survival of the bacterium in the human host. Galactose, mannose, and N-acetylglucosamine (GlcNAc) are likely
Externí odkaz:
https://doaj.org/article/bdee38d1436d4e96addc139af9ca7dc5
Autor:
Janine Lux, Lalaina Holivololona, Raquel San Millan Gutierrez, Markus Hilty, Alban Ramette, Manfred Heller, Lucy J. Hathaway
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Streptococcus pneumoniae colonizes the human nasopharynx, a multi-species microbial niche. Pneumococcal Ami-AliA/AliB oligopeptide permease is an ABC transporter involved in environmental sensing with peptides AKTIKITQTR, FNEMQPIVDRQ, and AI
Externí odkaz:
https://doaj.org/article/4687e06359c84aabbcea525c46f57e30
Autor:
Daniel A. Lujan, Joey L. Ochoa, Ellen J. Beswick, Tamara A. Howard, Helen J. Hathaway, Nora I. Perrone-Bizzozero, Rebecca S. Hartley
Publikováno v:
Biomedicines, Vol 12, Iss 2, p 340 (2024)
RNA binding proteins (RBPs) post-transcriptionally regulate gene expression by associating with regulatory sequences in the untranslated regions of mRNAs. Cold-inducible RBP (CIRP) is a stress-induced RBP that was recently shown to modulate inflammat
Externí odkaz:
https://doaj.org/article/fcacf9eb32fe48378d1920815b64581d
Autor:
Sujata Balasubramanian, Rachel Curtis-Robles, Bhagath Chirra, Lisa D. Auckland, Alan Mai, Virgilio Bocanegra-Garcia, Patti Clark, Wilhelmina Clark, Mark Cottingham, Geraldine Fleurie, Charles D. Johnson, Richard P. Metz, Shichen Wang, Nicholas J. Hathaway, Jeffrey A. Bailey, Gabriel L. Hamer, Sarah A. Hamer
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Knowledge of host associations of blood-feeding vectors may afford insights into managing disease systems and protecting public health. However, the ability of methods to distinguish bloodmeal sources varies widely. We used two methods—San
Externí odkaz:
https://doaj.org/article/7a1c1a84c2d0442d8dbad1ab06428492