Limited predictive value of the gut microbiome and metabolome for response to biological therapy in inflammatory bowel disease

Autor: Femke M. Prins, Iwan J. Hidding, Marjolein A.Y. Klaassen, Valerie Collij, Johannes P.D. Schultheiss, Werna T.C. Uniken Venema, Amber Bangma, Jurne B. Aardema, Bernadien H. Jansen, Wout G.N. Mares, Ben J.M. Witteman, Eleonora A.M. Festen, Gerard Dijkstra, Marijn C. Visschedijk, Herma H. Fidder, Arnau Vich Vila, Bas Oldenburg, Ranko Gacesa, Rinse K. Weersma

Publikováno v: Gut Microbes, Vol 16, Iss 1 (2024)

Emerging evidence suggests the gut microbiome’s potential in predicting response to biologic treatments in patients with inflammatory bowel disease (IBD). In this prospective study, we aimed to predict treatment response to vedolizumab and ustekinu

Externí odkaz: https://doaj.org/article/75c0bb382cf0416fa8df443a241eb914

DOP46 Mucosal host-microbe interactions associate with clinical phenotypes in Inflammatory Bowel Disease

Autor: A Bourgonje, S Hu, R Gacesa, B H Jansen, J R Björk, A Bangma, I J Hidding, H M van Dullemen, M C Visschedijk, K N Faber, G Dijkstra, H J M Harmsen, E A M Festen, A Vich Vila, L M Spekhorst, R K Weersma

Publikováno v: Journal of Crohn's and Colitis. 17:i113-i115

Background Host intestinal immune gene signatures and microbial dysregulations expose potential mechanisms in the pathogenesis of inflammatory bowel diseases (IBD). Profiling of mucosa-attached microbiota allows the understanding of locally present m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3bb5d8c968544a4880ec20fa6f516c20
https://doi.org/10.1093/ecco-jcc/jjac190.0086

Situational factors shape moral judgements in the trolley dilemma in Eastern, Southern and Western countries in a culturally diverse sample

Autor: Bence Bago, Marton Kovacs, John Protzko, Tamas Nagy, Zoltan Kekecs, Bence Palfi, Matus Adamkovic, Sylwia Adamus, Sumaya Albalooshi, Nihan Albayrak-Aydemir, Ilham N. Alfian, Sinan Alper, Sara Alvarez-Solas, Sara G. Alves, Santiago Amaya, Pia K. Andresen, Gulnaz Anjum, Daniel Ansari, Patrícia Arriaga, John Jamir Benzon R. Aruta, Alexios Arvanitis, Peter Babincak, Krystian Barzykowski, Bana Bashour, Ernest Baskin, Luisa Batalha, Carlota Batres, Jozef Bavolar, Fatih Bayrak, Benjamin Becker, Maja Becker, Anabel Belaus, Michał Białek, Ennio Bilancini, Daniel Boller, Leonardo Boncinelli, Jordane Boudesseul, Benjamin T. Brown, Erin M. Buchanan, Muhammad M. Butt, Dustin P. Calvillo, Nate C. Carnes, Jared B. Celniker, Christopher R. Chartier, William J. Chopik, Poom Chotikavan, Hu Chuan-Peng, Rockwell F. Clancy, Ogeday Çoker, Rita C. Correia, Vera Cubela Adoric, Carmelo P. Cubillas, Stefan Czoschke, Yalda Daryani, Job A. M. de Grefte, Wieteke C. de Vries, Elif G. Demirag Burak, Carina Dias, Barnaby J. W. Dixson, Xinkai Du, Francesca Dumančić, Andrei Dumbravă, Natalia B. Dutra, Janina Enachescu, Celia Esteban-Serna, Luis Eudave, Thomas R. Evans, Gilad Feldman, Fatima M. Felisberti, Susann Fiedler, Andrej Findor, Alexandra Fleischmann, Francesco Foroni, Radka Francová, Darius-Aurel Frank, Cynthia H. Y. Fu, Shan Gao, Omid Ghasemi, Ali-Reza Ghazi-Noori, Maliki E. Ghossainy, Isabella Giammusso, Tripat Gill, Biljana Gjoneska, Mario Gollwitzer, Aurélien Graton, Maurice Grinberg, Agata Groyecka-Bernard, Elizabeth A. Harris, Andree Hartanto, Widad A. N. M. Hassan, Javad Hatami, Katrina R. Heimark, Jasper J. J. Hidding, Evgeniya Hristova, Matej Hruška, Charlotte A. Hudson, Richard Huskey, Ayumi Ikeda, Yoel Inbar, Gordon P. D. Ingram, Ozan Isler, Chris Isloi, Aishwarya Iyer, Bastian Jaeger, Steve M. J. Janssen, William Jiménez-Leal, Biljana Jokić, Pavol Kačmár, Veselina Kadreva, Gwenaël Kaminski, Farzan Karimi-Malekabadi, Arno T. A. Kasper, Keith M. Kendrick, Bradley J. Kennedy, Halil E. Kocalar, Rabia I. Kodapanakkal, Marta Kowal, Elliott Kruse, Lenka Kučerová, Anton Kühberger, Anna O. Kuzminska, Fanny Lalot, Claus Lamm, Joris Lammers, Elke B. Lange, Anthony Lantian, Ivy Y.-M. Lau, Ljiljana B. Lazarevic, Marijke C. Leliveld, Jennifer N. Lenz, Carmel A. Levitan, Savannah C. Lewis, Manyu Li, Yansong Li, Haozheng Li, Tiago J. S. Lima, Samuel Lins, Marco Tullio Liuzza, Paula Lopes, Jackson G. Lu, Trent Lynds, Martin Máčel, Sean P. Mackinnon, Madhavilatha Maganti, Zoe Magraw-Mickelson, Leon F. Magson, Harry Manley, Gabriela M. Marcu, Darja Masli Seršić, Celine-Justine Matibag, Alan D. A. Mattiassi, Mahdi Mazidi, Joseph P. McFall, Neil McLatchie, Michael C. Mensink, Lena Miketta, Taciano L. Milfont, Alberto Mirisola, Michal Misiak, Panagiotis Mitkidis, Mehrad Moeini-Jazani, Arash Monajem, David Moreau, Erica D. Musser, Erita Narhetali, Danielle P. Ochoa, Jerome Olsen, Nicholas C. Owsley, Asil A. Özdoğru, Miriam Panning, Marietta Papadatou-Pastou, Neha Parashar, Philip Pärnamets, Mariola Paruzel-Czachura, Michal Parzuchowski, Julia V. Paterlini, Jeffrey M. Pavlacic, Mehmet Peker, Kim Peters, Liudmila Piatnitckaia, Isabel Pinto, Monica Renee Policarpio, Nada Pop-Jordanova, Annas J. Pratama, Maximilian A. Primbs, Ekaterina Pronizius, Danka Purić, Elisa Puvia, Vahid Qamari, Kun Qian, Alain Quiamzade, Beáta Ráczová, Diego A. Reinero, Ulf-Dietrich Reips, Cecilia Reyna, Kimberly Reynolds, Matheus F. F. Ribeiro, Jan P. Röer, Robert M. Ross, Petros Roussos, Fernando Ruiz-Dodobara, Susana Ruiz-Fernandez, Bastiaan T. Rutjens, Katarzyna Rybus, Adil Samekin, Anabela C. Santos, Nicolas Say, Christoph Schild, Kathleen Schmidt, Karolina A. Ścigała, MohammadHasan Sharifian, Jiaxin Shi, Yaoxi Shi, Erin Sievers, Miroslav Sirota, Michael Slipenkyj, Çağlar Solak, Agnieszka Sorokowska, Piotr Sorokowski, Sinem Söylemez, Niklas K. Steffens, Ian D. Stephen, Anni Sternisko, Laura Stevens-Wilson, Suzanne L. K. Stewart, Stefan Stieger, Daniel Storage, Justine Strube, Kyle J. Susa, Raluca D. Szekely-Copîndean, Natalia M. Szostak, Bagus Takwin, Srinivasan Tatachari, Andrew G. Thomas, Kevin E. Tiede, Lucas E. Tiong, Mirjana Tonković, Bastien Trémolière, Lauren V. Tunstead, Belgüzar N. Türkan, Mathias Twardawski, Miguel A. Vadillo, Zahir Vally, Leigh Ann Vaughn, Bruno Verschuere, Denis Vlašiček, Martin Voracek, Marek A. Vranka, Shuzhen Wang, Skye-Loren West, Stephen Whyte, Leigh S. Wilton, Anna Wlodarczyk, Xue Wu, Fei Xin, Su Yadanar, Hiroshi Yama, Yuki Yamada, Onurcan Yilmaz, Sangsuk Yoon, Danielle M. Young, Ilya Zakharov, Rizqy A. Zein, Ingo Zettler, Iris L. Žeželj, Don C. Zhang, Jin Zhang, Xiaoxiao Zheng, Rink Hoekstra, Balazs Aczel

Publikováno v: Nature Human Behaviour, 6, 6, pp. 880-895
Nature Human Behaviour, 6(6), 880-895. Nature Publishing Group
Nature Human Behaviour
Bago, B, Kovacs, M, Protzko, J, Nagy, T, Kekecs, Z, Palfi, B, Adamkovic, M, Adamus, S, Albalooshi, S, Albayrak-Aydemir, N, Alfian, I N, Alper, S, Alvarez-Solas, S, Alves, S G, Amaya, S, Andresen, P K, Anjum, G, Ansari, D, Arriaga, P, Aruta, J J B R, Arvanitis, A, Babincak, P, Barzykowski, K, Bashour, B, Baskin, E, Batalha, L, Batres, C, Bavolar, J, Bayrak, F, Becker, B, Becker, M, Belaus, A, Białek, M, Bilancini, E, Boller, D, Boncinelli, L, Boudesseul, J, Brown, B T, Buchanan, E M, Butt, M M, Calvillo, D P, Carnes, N C, Celniker, J B, Chartier, C R, Chopik, W J, Chotikavan, P, Chuan-Peng, H, Clancy, R F, Çoker, O, Correia, R C, Adoric, V C, Cubillas, C P, Czoschke, S, Daryani, Y, de Grefte, J A M, de Vries, W C, Burak, E G D, Dias, C, Dixson, B J W, Du, X, Dumančić, F, Dumbravă, A, Dutra, N B, Enachescu, J, Esteban-Serna, C, Eudave, L, Evans, T R, Feldman, G, Felisberti, F M, Fiedler, S, Findor, A, Fleischmann, A, Foroni, F, Francová, R, Frank, D A, Fu, C H Y, Gao, S, Ghasemi, O, Ghazi-Noori, A R, Ghossainy, M E, Giammusso, I, Gill, T, Gjoneska, B, Gollwitzer, M, Graton, A, Grinberg, M, Groyecka-Bernard, A, Harris, E A, Hartanto, A, Hassan, W A N M, Hatami, J, Heimark, K R, Hidding, J J J, Hristova, E, Hruška, M, Hudson, C A, Huskey, R, Ikeda, A, Inbar, Y, Ingram, G P D, Isler, O, Isloi, C, Iyer, A, Jaeger, B, Janssen, S M J, Jiménez-Leal, W, Jokić, B, Kačmár, P, Kadreva, V, Kaminski, G, Karimi-Malekabadi, F, Kasper, A T A, Kendrick, K M, Kennedy, B J, Kocalar, H E, Kodapanakkal, R I, Kowal, M, Kruse, E, Kučerová, L, Kühberger, A, Kuzminska, A O, Lalot, F, Lamm, C, Lammers, J, Lange, E B, Lantian, A, Lau, I Y M, Lazarevic, L B, Leliveld, M C, Lenz, J N, Levitan, C A, Lewis, S C, Li, M, Li, Y, Li, H, Lima, T J S, Lins, S, Liuzza, M T, Lopes, P, Lu, J G, Lynds, T, Máčel, M, Mackinnon, S P, Maganti, M, Magraw-Mickelson, Z, Magson, L F, Manley, H, Marcu, G M, Seršić, D M, Matibag, C J, Mattiassi, A D A, Mazidi, M, McFall, J P, McLatchie, N, Mensink, M C, Miketta, L, Milfont, T L, Mirisola, A, Misiak, M, Mitkidis, P, Moeini-Jazani, M, Monajem, A, Moreau, D, Musser, E D, Narhetali, E, Ochoa, D P, Olsen, J, Owsley, N C, Özdoğru, A A, Panning, M, Papadatou-Pastou, M, Parashar, N, Pärnamets, P, Paruzel-Czachura, M, Parzuchowski, M, Paterlini, J V, Pavlacic, J M, Peker, M, Peters, K, Piatnitckaia, L, Pinto, I, Policarpio, M R, Pop-Jordanova, N, Pratama, A J, Primbs, M A, Pronizius, E, Purić, D, Puvia, E, Qamari, V, Qian, K, Quiamzade, A, Ráczová, B, Reinero, D A, Reips, U D, Reyna, C, Reynolds, K, Ribeiro, M F F, Röer, J P, Ross, R M, Roussos, P, Ruiz-Dodobara, F, Ruiz-Fernandez, S, Rutjens, B T, Rybus, K, Samekin, A, Santos, A C, Say, N, Schild, C, Schmidt, K, Ścigała, K A, Sharifian, M H, Shi, J, Shi, Y, Sievers, E, Sirota, M, Slipenkyj, M, Solak, Ç, Sorokowska, A, Sorokowski, P, Söylemez, S, Steffens, N K, Stephen, I D, Sternisko, A, Stevens-Wilson, L, Stewart, S L K, Stieger, S, Storage, D, Strube, J, Susa, K J, Szekely-Copîndean, R D, Szostak, N M, Takwin, B, Tatachari, S, Thomas, A G, Tiede, K E, Tiong, L E, Tonković, M, Trémolière, B, Tunstead, L V, Türkan, B N, Twardawski, M, Vadillo, M A, Vally, Z, Vaughn, L A, Verschuere, B, Vlašiček, D, Voracek, M, Vranka, M A, Wang, S, West, S L, Whyte, S, Wilton, L S, Wlodarczyk, A, Wu, X, Xin, F, Yadanar, S, Yama, H, Yamada, Y, Yilmaz, O, Yoon, S, Young, D M, Zakharov, I, Zein, R A, Zettler, I, Žeželj, I L, Zhang, D C, Zhang, J, Zheng, X, Hoekstra, R & Aczel, B 2022, ' Situational factors shape moral judgements in the trolley dilemma in Eastern, Southern and Western countries in a culturally diverse sample ', Nature Human Behaviour, vol. 6, no. 6, pp. 880-895 . https://doi.org/10.1038/s41562-022-01319-5
Nature Human Behaviour, 6, 880-895
Bago, B, Kovacs, M, Protzko, J, Nagy, T, Kekecs, Z, Palfi, B, Adamkovic, M, Adamus, S, Albalooshi, S, Albayrak-Aydemir, N, Alfian, I N, Alper, S, Alvarez-Solas, S, Alves, S G, Amaya, S, Andresen, P K, Anjum, G, Ansari, D, Arriaga, P, Aruta, J J B R, Arvanitis, A, Babincak, P, Barzykowski, K, Bashour, B, Baskin, E, Batalha, L, Batres, C, Bavolar, J, Bayrak, F, Becker, B, Becker, M, Belaus, A, Bialek, M, Bilancini, E, Boller, D, Boncinelli, L, Boudesseul, J, Brown, B T, Buchanan, E M, Butt, M M, Calvillo, D P, Carnes, N C, Celniker, J B, Chartier, C R, Chopik, W J, Chotikavan, P, Chuan-Peng, H, Clancy, R F, Coker, O, Correia, R C, Adoric, V C, Cubillas, C P, Czoschke, S, Daryani, Y, de Grefte, J A M, de Vries, W C, Burak, E G D, Dias, C, Dixson, B J W, Du, X, Dumancic, F, Dumbrava, A, Dutra, N B, Enachescu, J, Esteban-Serna, C, Eudave, L, Evans, T R, Feldman, G, Felisberti, F M, Fiedler, S, Findor, A, Fleischmann, A, Foroni, F, Francova, R, Frank, D-A, Fu, C H Y, Gao, S, Ghasemi, O, Ghazi-Noori, A-R, Ghossainy, M E, Giammusso, I, Gill, T, Gjoneska, B, Gollwitzer, M, Graton, A, Grinberg, M, Groyecka-Bernard, A, Harris, E A, Hartanto, A, Hassan, W A N M, Hatami, J, Heimark, K R, Hidding, J J J, Hristova, E, Hruska, M, Hudson, C A, Huskey, R, Ikeda, A, Inbar, Y, Ingram, G P D, Isler, O, Isloi, C, Iyer, A, Jaeger, B, Janssen, S M J, Jimenez-Leal, W, Jokic, B, Kacmar, P, Kadreva, V, Kaminski, G, Karimi-Malekabadi, F, Kasper, A T A, Kendrick, K M, Kennedy, B J, Kocalar, H E, Kodapanakkal, R I, Kowal, M, Kruse, E, Kucerova, L, Kuehberger, A, Kuzminska, A O, Lalot, F, Lamm, C, Lammers, J, Lange, E B, Lantian, A, Lau, I Y-M, Lazarevic, L B, Leliveld, M C, Lenz, J N, Levitan, C A, Lewis, S C, Li, M, Li, Y, Li, H, Lima, T J S, Lins, S, Liuzza, M T, Lopes, P, Lu, J G, Lynds, T, Macel, M, Mackinnon, S P, Maganti, M, Magraw-Mickelson, Z, Magson, L F, Manley, H, Marcu, G M, Sersic, D M, Matibag, C-J, Mattiassi, A D A, Mazidi, M, McFall, J P, McLatchie, N, Mensink, M C, Miketta, L, Milfont, T L, Mirisola, A, Misiak, M, Mitkidis, P, Moeini-Jazani, M, Monajem, A, Moreau, D, Musser, E D, Narhetali, E, Ochoa, D P, Olsen, J, Owsley, N C, Ozdogru, A A, Panning, M, Papadatou-Pastou, M, Parashar, N, Parnamets, P, Paruzel-Czachura, M, Parzuchowski, M, Paterlini, J V, Pavlacic, J M, Peker, M, Peters, K, Piatnitckaia, L, Pinto, I, Policarpio, M R, Pop-Jordanova, N, Pratama, A J, Primbs, M A, Pronizius, E, Puric, D, Puvia, E, Qamari, V, Qian, K, Quiamzade, A, Raczova, B, Reinero, D A, Reips, U-D, Reyna, C, Reynolds, K, Ribeiro, M F F, Roeer, J P, Ross, R M, Roussos, P, Ruiz-Dodobara, F, Ruiz-Fernandez, S, Rutjens, B T, Rybus, K, Samekin, A, Santos, A C, Say, N, Schild, C, Schmidt, K, Scigala, K A, Sharifian, M, Shi, J, Shi, Y, Sievers, E, Sirota, M, Slipenkyj, M, Solak, C, Sorokowska, A, Sorokowski, P, Soylemez, S, Steffens, N K, Stephen, I D, Sternisko, A, Stevens-Wilson, L, Stewart, S L K, Stieger, S, Storage, D, Strube, J, Susa, K J, Szekely-Copindean, R D, Szostak, N M, Takwin, B, Tatachari, S, Thomas, A G, Tiede, K E, Tiong, L E, Tonkovic, M, Tremoliere, B, Tunstead, L V, Turkan, B N, Twardawski, M, Vadillo, M A, Vally, Z, Vaughn, L A, Verschuere, B, Vlasicek, D, Voracek, M, Vranka, M A, Wang, S, West, S-L, Whyte, S, Wilton, L S, Wlodarczyk, A, Wu, X, Xin, F, Yadanar, S, Yama, H, Yamada, Y, Yilmaz, O, Yoon, S, Young, D M, Zakharov, I, Zein, R A, Zettler, I, Zezelj, I L, Zhang, D C, Zhang, J, Zheng, X, Hoekstra, R & Aczel, B 2022, ' Situational factors shape moral judgements in the trolley dilemma in Eastern, Southern and Western countries in a culturally diverse sample ', Nature Human Behaviour, vol. 6, no. 6, pp. 880-895 . https://doi.org/10.1038/s41562-022-01319-5
Repositorio Institucional-Ulima
Universidad de Lima
Paediatrics Publications
Nature Human Behaviour, 6, 880-895. Nature Publishing Group
Repositorio Universidad Regional Amazónica
Universidad Regional Amazónica
instacron:IKIAM
Nature Human Behaviour, 6(6), 880-895. Springer Nature

The study of moral judgements often centres on moral dilemmas in which options consistent with deontological perspectives (that is, emphasizing rules, individual rights and duties) are in conflict with options consistent with utilitarian judgements (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3e808ca09f8ea6b9f0121e4246c161
https://repository.ubn.ru.nl/handle/2066/249463

Mucosal host–microbe interactions associate with clinical phenotypes in inflammatory bowel disease

Autor: Shixian Hu, Arno R. Bourgonje, Ranko Gacesa, Bernadien H. Jansen, Johannes R. Björk, Amber Bangma, Iwan J. Hidding, Hendrik M. van Dullemen, Marijn C. Visschedijk, Klaas Nico Faber, Gerard Dijkstra, Hermie J. M. Harmsen, Eleonora A. M. Festen, Arnau Vich Vila, Lieke M. Spekhorst, Rinse K. Weersma

Dysregulation of gut mucosal host–microbe interactions is a central feature of inflammatory bowel disease (IBD). To study tissue-specific interactions, we performed transcriptomic (RNA-seq) and microbial (16S-rRNA-seq) profiling of 696 intestinal b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a69ea117c56f6920813a2cbfc3a6a55
https://doi.org/10.1101/2022.06.04.494807

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