Zobrazeno 1 - 10
of 22
pro vyhledávání: '"J H Van Es"'
Publikováno v:
The Journal of Immunology. 151:6569-6576
The Ig VH regions of virtually all human pathogenic cold agglutinin (CA) anti-i/l autoantibodies are encoded by a single Ig VH gene segment, VH4.21, in conjunction with a highly variable CDR3 structure. The anti-I specificity is often associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e0d86a291da4671e32b78fd5ba8de6a
https://doi.org/10.4049/jimmunol.151.11.6569
https://doi.org/10.4049/jimmunol.151.11.6569
Publikováno v:
The Journal of Immunology. 150:161-168
We have developed a mAb (JE-6) that recognizes an Id encoded by the most JH-proximal human VH gene segment (VH6) in or near germ-line configuration. This mAb was used to determine the frequency of Id JE6+ B cells in large collections of monoclonal EB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43b11547f850503206f4eac391e3d243
https://doi.org/10.4049/jimmunol.150.1.161
https://doi.org/10.4049/jimmunol.150.1.161
Publikováno v:
The Journal of Immunology. 149:2234-2240
We report the Ig H and L chain V region sequences from the cDNAs encoding a monoclonal human IgG anti-cardiolipin/ssDNA autoantibody (R149) derived from a patient with active SLE. Comparison with the germ-line V-gene repertoire of this patient reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0178ec65c90a3dd928712357cb8bda44
https://doi.org/10.4049/jimmunol.149.6.2234
https://doi.org/10.4049/jimmunol.149.6.2234
Publikováno v:
The Journal of Immunology. 149:492-497
We have generated a mouse x human heterohybridoma that contains a single copy of chromosome 14 and, thus, a haploid set of Ig VH genes. This cell line was used to investigate the germ-line content and nucleotide sequences of members of the VH4 gene f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecaf7eebae0333e851250b97b6ef6d09
https://doi.org/10.4049/jimmunol.149.2.492
https://doi.org/10.4049/jimmunol.149.2.492
Autor:
Nick Barker, J H van Es, Hans Clevers, Maria Kasper, Hugo J. Snippert, Viljar Jaks, Rune Toftgård
Publikováno v:
Cold Spring Harbor symposia on quantitative biology. 73
The intestinal epithelium and the hair follicle represent examples of rapidly self-renewing tissue in adult mammals. We have recently identified a novel stem cell gene Lgr5 expressed in multiple adult tissues. At the bottoms of crypts in small intest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42480c3d464837c8ddbbf6f161167760
https://pubmed.ncbi.nlm.nih.gov/19478326
https://pubmed.ncbi.nlm.nih.gov/19478326
Autor:
F.H.J. Gmelig Meyling, J. H. Van Es, R. H. W. M. Derksen, Ton Logtenberg, H. Aanstoot, W R van de Akker
Publikováno v:
The Journal of Experimental Medicine
The processes that govern the generation of pathogenic anti-DNA autoantibodies in human systemic lupus erythematosus (SLE) are largely unknown. Autoantibodies may arise as a consequence of polyclonal B cell activation and/or antigen-driven B cell act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75687d159247cdc53cb8e435b158e886
http://europepmc.org/articles/PMC2118793
http://europepmc.org/articles/PMC2118793
Publikováno v:
Biological Chemistry, 383, 255-261. Walter De Gruyter
The Wnt signalling cascade plays an important role during embryonic patterning and cell fate determination and is highly conserved throughout evolution. Factors of the TCF/LEF HMG domain family (Tcfs) are the downstream effectors of this signal trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f7587326a40008d3a3099e095a88eb
https://pubmed.ncbi.nlm.nih.gov/11934263
https://pubmed.ncbi.nlm.nih.gov/11934263
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 151(11)
The Ig VH regions of virtually all human pathogenic cold agglutinin (CA) anti-i/l autoantibodies are encoded by a single Ig VH gene segment, VH4.21, in conjunction with a highly variable CDR3 structure. The anti-I specificity is often associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49c8bb6222434d57ac1fb5262bcb90aa
https://pubmed.ncbi.nlm.nih.gov/7504024
https://pubmed.ncbi.nlm.nih.gov/7504024
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 150(1)
We have developed a mAb (JE-6) that recognizes an Id encoded by the most JH-proximal human VH gene segment (VH6) in or near germ-line configuration. This mAb was used to determine the frequency of Id JE6+ B cells in large collections of monoclonal EB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f9d8e26e05d6554582a32edd7755702
https://pubmed.ncbi.nlm.nih.gov/8417121
https://pubmed.ncbi.nlm.nih.gov/8417121
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 149(6)
We report the Ig H and L chain V region sequences from the cDNAs encoding a monoclonal human IgG anti-cardiolipin/ssDNA autoantibody (R149) derived from a patient with active SLE. Comparison with the germ-line V-gene repertoire of this patient reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce91f06aa73f6f37ac3273e490eda5e5
https://pubmed.ncbi.nlm.nih.gov/1517580
https://pubmed.ncbi.nlm.nih.gov/1517580