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Autor:
Jeffrey S. Kasher, Joseph M. Indelicato, David A. Preston, Donald B. Boyd, G. K. Cook, J H McDonald rd, William E. Alborn, Carol Elaine Pasini, J. A. Eudaly, R Johnson
Publikováno v:
Journal of Medicinal Chemistry. 32:2442-2450
A series of structurally unique 1-carba-1-dethiacephems is described. The structural stability of the 1-carba-1-dethiacephem nucleus was essential for the preparation of this series of 3-quaternary ammonium carbacephems. The known p-nitrobenzyl 7 bet