Zobrazeno 1 - 10 of 69 pro vyhledávání: '"J H Kimura"'
1
Cancellous bone biomechanics
Autor: J. H. Kimura, David P. Fyhrie
Publikováno v: Journal of Biomechanics. 32:1139-1148
Cancellous bone is both a biological and a mechanical structure. The interaction between these two aspects of cancellous bone is sufficiently strong that understanding the mechanical properties of the tissue is not possible without consideration of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed7f101dfd5a71575b5afd31116a23a5
https://doi.org/10.1016/s0021-9290(99)00114-1
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2
Heterogeneity of keratan sulfate substituted on human chondrocytic large proteoglycans
Autor: J H Kimura, Joel A. Block, Sven Inerot
Publikováno v: Journal of Biological Chemistry. 267:7245-7252
Newly synthesized 35S-labeled chondrocytic keratan sulfate chains were generated by chondrocytes of human chondrosarcoma cell line 105KC and were analyzed for heterogeneity of regional substitution, hydrodynamic size, and charge density. After isolat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d51406d6fc338804a7ce49d3fd71766
https://doi.org/10.1016/s0021-9258(18)42511-2
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3
Synthesis of chondrocytic keratan sulphate-containing proteoglycans by human chondrosarcoma cells in long-term cell culture
Autor: S. Gitelis, Joel A. Block, J H Kimura, Sven Inerot
Publikováno v: The Journal of Bone & Joint Surgery. 73:647-658
Keratan sulphate is an integral component of the large aggregating proteoglycans of mature human articular cartilage. The keratan sulphate content of chondrocytic proteoglycans increases during maturation, and it is a useful marker of mature-type cho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a31df0902e235ec63f329f87b7ad269e
https://doi.org/10.2106/00004623-199173050-00002
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4
The Effects of Long Term Monolayer Culture on the Proteoglycan Phenotype of a Clonal Population of Mature Human Malignant Chondrocytes
Autor: Joel A. Block, J H Kimura, Sven Inerot, Steven Gitelis
Publikováno v: Connective Tissue Research. 26:295-313
Articular cartilage chondrocytes maintain biosynthetic heterogeneity in cell culture, but undergo irreversible dedifferentiation of their proteoglycan phenotype, as defined by keratan sulfate content. A recently described cell line of malignant human
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e77c9850983c8845875c523a7ffc0f
https://doi.org/10.3109/03008209109152446
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5
Biochemical characterization of long-term culture of the swarm rat chondrosarcoma chondrocytes in agarose
Autor: Klaus E. Kuettner, Anna M. Kucharska, J H Kimura
Publikováno v: Journal of Orthopaedic Research. 8:781-792
Difficulty in maintaining phenotypic stability of the Swarm rat chondrosarcoma in long-term monolayer cultures has prompted investigation of alternative conditions that would enable extended maintenance of these cells, permitting use of the tumor as
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1175b6a4b07e8c901080877cc2436d3
https://doi.org/10.1002/jor.1100080602
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6
Use of a new rat chondrosarcoma cell line to delineate a 119-base pair chondrocyte-specific enhancer element and to define active promoter segments in the mouse pro-alpha 1(II) collagen gene
Autor: Silvio Garofalo, J. H. Kimura, Guang Zhou, B de Crombrugghe, K. Mukhopadhyay, Véronique Lefebvre
Publikováno v: The Journal of biological chemistry. 270(46)
We show that a new rat chondrosarcoma (RCS) cell line established in long-term culture from the Swarm tumor displayed a stable differentiated chondrocyte-like phenotype. Indeed, these cells produced the collagen types II, IX, and XI and alcian blue-s
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https://pubmed.ncbi.nlm.nih.gov/7499238
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7
Cell-mediated catabolism of aggrecan. Evidence that cleavage at the 'aggrecanase' site (Glu373-Ala374) is a primary event in proteolysis of the interglobular domain
Autor: M W, Lark, J T, Gordy, J R, Weidner, J, Ayala, J H, Kimura, H R, Williams, R A, Mumford, C R, Flannery, S S, Carlson, M, Iwata
Publikováno v: The Journal of biological chemistry. 270(6)
A rat chondrosarcoma cell line and primary bovine chondrocytes have been used to study cell-mediated aggrecan catabolism. Addition of 1 microM retinoic acid to chondrosarcoma cultures resulted in aggrecan proteolysis with the release of greater than
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https://pubmed.ncbi.nlm.nih.gov/7852317
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8
Synthesis of chondrocytic keratan sulphate-containing proteoglycans by human chondrosarcoma cells in long-term cell culture
Autor: J A, Block, S E, Inerot, S, Gitelis, J H, Kimura
Publikováno v: The Journal of bone and joint surgery. American volume. 73(5)
Keratan sulphate is an integral component of the large aggregating proteoglycans of mature human articular cartilage. The keratan sulphate content of chondrocytic proteoglycans increases during maturation, and it is a useful marker of mature-type cho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8e962d37c6d38b0e86b5a2f49616c80f
https://pubmed.ncbi.nlm.nih.gov/2045389
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10
Studies on the biosynthesis of cartilage proteoglycan in a model system of cultured chondrocytes from the Swarm rat chondrosarcoma
Autor: Vincent C. Hascall, L. Stefan Lohmander, J H Kimura
Publikováno v: Scopus-Elsevier
Biosynthesis of cartilage proteoglycan was examined in a model system of cultured chondrocytes from a transplantable rat chondrosarcoma. Extensive modification with the addition of chondroitin sulfate glycosaminoglycan, N-linked oligosaccharide, and
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https://doi.org/10.1002/jcb.240260406
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