Zobrazeno 1 - 10
of 95
pro vyhledávání: '"J H Hoofnagle"'
Autor:
B, Hameed, N A, Terrault, R M, Gill, R, Loomba, N, Chalasani, J H, Hoofnagle, M L, Van Natta, Katherine, Yates
Publikováno v:
Alimentary Pharmacology & Therapeutics. 47:645-656
SummaryBackground In a 72-week, randomised controlled trial of obeticholic acid (OCA) in non-alcoholic steatohepatitis (NASH), OCA was superior to placebo in improving serum ALT levels and liver histology. OCA therapy also reduced weight. Aims Becaus
Autor:
Y, Rotman, B B, Borg, A, Soza, J J, Feld, A A, Modi, R, Loomba, G, Lutchman, E, Rivera, E, Doo, M G, Ghany, T, Heller, A U, Neumann, T J, Liang, J H, Hoofnagle
Publikováno v:
Alimentary pharmacologytherapeutics. 31(9)
Chronic infection with hepatitis C, genotype 2/3, responds better than other genotypes to peginterferon and ribavirin treatment. We hypothesized that a lower dose of peginterferon would be as effective, but less toxic than standard doses.To test the
Autor:
L B Seeff, J H Hoofnagle
Publikováno v:
Oncogene. 25(27)
Hepatocellular carcinoma (HCC) ranks among the 10 most common cancers worldwide. It evolves from several chronic liver diseases, most of which culminate in cirrhosis. As the most common causes, other than alcoholic cirrhosis, are chronic hepatitis B
Autor:
J H Hoofnagle, D Herion
Publikováno v:
Hepatology. 25:769-771
Autor:
J H Hoofnagle, Edward Doo
Publikováno v:
Gut. 46(4)
BACKGROUND, AIM, AND METHODS—Alpha interferon is the generally approved therapy for HBe antigen positive patients with chronic hepatitis B, but its efficacy is limited. Lamivudine is a new oral nucleoside analogue which potently inhibits hepatitis
Autor:
K R, Reddy, J H, Hoofnagle, M J, Tong, W M, Lee, P, Pockros, E J, Heathcote, D, Albert, T, Joh
Publikováno v:
Hepatology (Baltimore, Md.). 30(3)
The likelihood of a sustained response to a course of interferon in patients with chronic hepatitis C correlates with several clinical and viral factors, including age, viral genotype and initial levels of hepatitis C virus (HCV) RNA in serum. The ro
Publikováno v:
Digestive diseases and sciences. 43(10)
Pruritus is a common symptom in cholestatic liver disease but is rare in chronic hepatitis C. Eight patients with chronic hepatitis C and severe pruritus were compared with regard to biochemical, serological, and histological features to eight diseas
Autor:
R K, Zetterman, S H, Belle, J H, Hoofnagle, S, Lawlor, Y, Wei, J, Everhart, R H, Wiesner, J R, Lake
Publikováno v:
Transplantation. 66(4)
The average age of liver transplant recipients has increased steadily during the last decade. The effects of recipient age on outcome of liver transplantation were evaluated in a large prospective database.A total of 735 adult recipients of single-or
Autor:
J E, Everhart, M, Lombardero, K M, Detre, R K, Zetterman, R H, Wiesner, J R, Lake, J H, Hoofnagle
Publikováno v:
Transplantation. 64(9)
Waiting time to liver transplantation (LTx) has dramatically lengthened, but the proportion of candidates who die awaiting transplantation has not increased. We evaluated whether longer waiting time for LTx candidates increases mortality.A cohort of