Zobrazeno 1 - 5
of 5
pro vyhledávání: '"J H De Maeyer"'
Autor:
Victor W S Kung, Qasim Aziz, J H De Maeyer, Charles H. Knowles, John Broad, Gareth J. Sanger, George Boundouki
Publikováno v:
British Journal of Pharmacology. 170:1253-1261
Background and Purpose Cholinesterase inhibitors such as neostigmine are used for acute colonic pseudo-obstruction, but cardio-bronchial side-effects limit use. To minimize side-effects, lower doses could be combined with a 5-HT4 receptor agonist, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ae2e0037c96b82ac7bcf181e720a593
https://doi.org/10.1111/bph.12397
https://doi.org/10.1111/bph.12397
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 385:565-577
We studied how 5-HT(4) receptor-mediated inotropic responses are regulated at the level of cAMP in porcine left atrium. We used selective phosphodiesterase (PDE) inhibitors to assess which PDE subtypes are responsible for the fade with time of inotro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9f98542bfc951fb1dc17136c35f663
https://doi.org/10.1007/s00210-012-0746-y
https://doi.org/10.1007/s00210-012-0746-y
Publikováno v:
Neurogastroenterology & Motility. 20:99-112
5-Hydroxytryptamine(4) (5-HT(4)) receptors are an interesting target for the management of patients in need of gastrointestinal (GI) promotility treatment. They have proven therapeutic potential to treat patients with GI motility disorders. Lack of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61136c4b6cd50e739d4587d5d5b71c1e
https://doi.org/10.1111/j.1365-2982.2007.01059.x
https://doi.org/10.1111/j.1365-2982.2007.01059.x
Publikováno v:
British journal of pharmacology. 170(6)
Cholinesterase inhibitors such as neostigmine are used for acute colonic pseudo-obstruction, but cardio-bronchial side-effects limit use. To minimize side-effects, lower doses could be combined with a 5-HT4 receptor agonist, which also facilitates in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9164e3f8e5f4c4b40b123e08122761c0
https://pubmed.ncbi.nlm.nih.gov/24032987
https://pubmed.ncbi.nlm.nih.gov/24032987
Autor:
Lin Chang, Stefan Müller-Lissner, Eamonn Martin Quigley, James J. Galligan, Michael Camilleri, Jan Tack, Vincenzo Stanghellini, J. H. De Maeyer, J. A. J. Schuurkes, William D. Chey, Brian E. Lacy
Publikováno v:
Alimentary Pharmacology & Therapeutics
BACKGROUND: The nonselective 5-HT(4) receptor agonists, cisapride and tegaserod have been associated with cardiovascular adverse events (AEs). AIM: To perform a systematic review of the safety profile, particularly cardiovascular, of 5-HT(4) agonists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5bd842e6dd1e77f948569ea41974ce0
https://pubmed.ncbi.nlm.nih.gov/22500472
https://pubmed.ncbi.nlm.nih.gov/22500472