Zobrazeno 1 - 10
of 42
pro vyhledávání: '"J H, van Dierendonck"'
Publikováno v:
Cell Proliferation. 36:293-306
The 26-kDa bcl-2 gene product inhibits apoptosis and cell proliferation. Cleavage of Bcl-2 into a 22-kDa fragment inactivates its anti-apoptotic activity and is a key event in apoptosis. Here, and in recent work, we describe massive 19-kDa Bcl-2 immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07deb1163d77b1cdcd8348a2e00a6ee5
https://doi.org/10.1046/j.1365-2184.2003.00286.x
https://doi.org/10.1046/j.1365-2184.2003.00286.x
Autor:
R. Keijzer, Rob W.M. Hoetelmans, C.J.H. van de Velde, R. L. P. Van Vlierberghe, Alexander L. Vahrmeijer, J. H. Van Dierendonck, Gerard J. Mulder
Publikováno v:
Cell Proliferation. 36:35-44
Reduced cell proliferation and increased levels of cellular glutathione (GSH) are characteristic for cells that overexpress the anti-apoptotic Bcl-2 protein. We investigated the influence of various Bcl-2 domains on both these characteristics. Rat CC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c218a96480a443b4b96925dbe88d7c1a
https://doi.org/10.1046/j.1365-2184.2003.00252.x
https://doi.org/10.1046/j.1365-2184.2003.00252.x
Publikováno v:
Biotechnic & Histochemistry. 77:137-144
Immunohistochemical detection of expression of the anti-apoptotic Bcl-2 protein is widely studied as a putative prognostic and predictive factor in various types of cancer. For that purpose, heating for 10 min by microwave (MW) up to 100o C in citrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc636b2ea6975976db3daadf02d8ee16
https://doi.org/10.1080/bih.77.3.137.144
https://doi.org/10.1080/bih.77.3.137.144
Autor:
J. Schutrups, C.J.H. van de Velde, J. H. Van Dierendonck, Gerard J. Mulder, Alexander L. Vahrmeijer
Publikováno v:
Cancer Chemotherapy and Pharmacology. 44:111-116
Purpose: Glutathione (GSH) plays an important role in the resistance of tumors to cytostatics. Therefore, depletion of GSH by the GSH synthesis inhibitor buthionine sulfoximine (BSO) has been proposed to enhance the efficacy of certain anticancer age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c5b015ed7d0c1376ced3f6d1c525cc9
https://doi.org/10.1007/s002800050954
https://doi.org/10.1007/s002800050954
Autor:
Rob C. Hoeben, Alexandra Maria Pietersen, H J Rademaker, C.J.H. van de Velde, Mathieu H.M. Noteborn, H. van Ormondt, Martijn J. W. E. Rabelink, D Masman, Peter J. K. Kuppen, J. H. Van Dierendonck, A. J. Van Der Eb, M. M. Van Der Eb, D J M van den Wollenberg
Publikováno v:
Gene Therapy. 6:882-892
Specificity is an essential prerequisite for cancer gene therapy. Recently we described that apoptin, a protein of 121 amino acids which is derived from the chicken anemia virus, induces programmed cell death or apoptosis in transformed and malignant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ceeda3ee802273c23479273ef82d8f
https://doi.org/10.1038/sj.gt.3300876
https://doi.org/10.1038/sj.gt.3300876
Autor:
J.H.J.M. van Krieken, L.C.J.M. van den Broek, H.-J. van Slooten, K. M. J. Nelemans, David J. Bruinvels, J. H. Van Dierendonck, J. Hermans, Rob A. E. M. Tollenaar
Publikováno v:
British Journal of Cancer
To evaluate the prognostic significance of immunohistochemically detected p53 and Bcl-2 proteins in colorectal cancer, tissue sections from 238 paraffin-embedded colorectal carcinomas were immunostained for p53 (MAb DO-7 and CM-1 antiserum) and Bcl-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6adb80540c71ef9bf54a9f897d83aeed
https://doi.org/10.1038/bjc.1998.306
https://doi.org/10.1038/bjc.1998.306
Autor:
J.H.J.M. van Krieken, A. J. Van Der Eb, C. W. Van Der Houven Van Oordt, M. L. Breuer, Theo G. Schouten, J. H. Van Dierendonck
Publikováno v:
Carcinogenesis. 19:847-853
Transgenic mice overexpressing the pim-1 oncogene in their lymphoid compartment display a low incidence of spontaneous T-cell lymphomas, but are highly susceptible to point mutation-inducing genotoxic carcinogens. We show here that total body X-irrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a17daf2ab352c2f080ed40cc3fdfc49
https://doi.org/10.1093/carcin/19.5.847
https://doi.org/10.1093/carcin/19.5.847
Publikováno v:
British Journal of Cancer
British journal of cancer, 77(5), 789-796. Nature Publishing Group
British journal of cancer, 77(5), 789-796. Nature Publishing Group
Bcl-2 has been demonstrated to inhibit apoptosis in breast cancer cells in vitro, and the ratio between Bcl-2 and its proapoptotic homologue Bax seems to be an important determinant of cellular sensitivity to induction of apoptosis. However, little i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338c83fa169a170729342b00292ed45c
https://doi.org/10.1038/bjc.1998.128
https://doi.org/10.1038/bjc.1998.128
Autor:
A.L. Vahrmeijer, J. J. Schuitmaker, Onno T. Terpstra, Jeroen P. Rovers, J. H. Van Dierendonck
Publikováno v:
British Journal of Cancer
Bacteriochlorin a (BCA) is a second-generation photosensitizer that is effective in tumour destruction upon illumination with light of a wavelength of 760 nm. Tissue penetration by light at this wavelength is greater compared with wavelengths at whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2031a6bf4caa605804b3824869d3019
http://europepmc.org/articles/PMC2150378
http://europepmc.org/articles/PMC2150378
Autor:
H S Smith, B A Bonsing, J. H. Van Dierendonck, G T Colbern, C. J. Cornelisse, A J Hiller, H.-J. Van Slooten
Publikováno v:
British Journal of Cancer
The effect of co-inoculation of basement membrane matrix, Matrigel and two human breast cancer cell lines, BT-474 and SK-BR-3, was tested in immune-deficient mice. Both cell lines strongly overexpress c-ErbB-2 protein, whereas only BT-474 is reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913f46bc6fdec32984b81eb38b9928d6
https://doi.org/10.1038/bjc.1995.271
https://doi.org/10.1038/bjc.1995.271